Burkhard Göke
Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease
Seiderer J, Reinecker H, Lohse P, Ochsenkühn T, Göke B, Müller-Myhsok B, Jürgens M, Pfennig S, Niess J, Glas J, Tillack C, Leistner D, Dambacher J, Brand S. Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease. Clin Immunol 2008; 127:49-55.
11.01.2008Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease
11.01.2008Clin Immunol 2008; 127:49-55
Seiderer Julia, Reinecker Hans-Christian, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Müller-Myhsok Bertram, Jürgens Matthias, Pfennig Simone, Niess Jan-Hendrik, Glas Jürgen, Tillack Cornelia, Leistner Dorothea, Dambacher Julia, Brand Stephan
The role of interleukin-22 in hepatitis C virus infection
Dambacher J, Beigel F, Zitzmann K, Heeg M, Göke B, Diepolder H, Auernhammer C, Brand S. The role of interleukin-22 in hepatitis C virus infection. Cytokine 2008; 41:209-16.
11.01.2008The role of interleukin-22 in hepatitis C virus infection
11.01.2008Cytokine 2008; 41:209-16
Dambacher Julia, Beigel Florian, Zitzmann Kathrin, Heeg Malte H J, Göke Burkhard, Diepolder Helmut M, Auernhammer Christoph J, Brand Stephan
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
Glas J, Klein W, Epplen J, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Griga T, Haller D, Pfennig S, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török H, Tonenchi L, Brand S. The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2007; 103:682-91.
20.12.2007The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
20.12.2007Am J Gastroenterol 2007; 103:682-91
Glas Jürgen, Klein Wolfram, Epplen Jörg T, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Mussack Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Griga Thomas, Haller Dirk, Pfennig Simone, Konrad Astrid, Schmechel Silke, Dambacher Julia, Seiderer Julia, Schroff Frieder, Wetzke Martin, Roeske Darina, Török Helga-Paula, Tonenchi Laurian, Brand Stephan
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants
Glas J, Epplen J, Schiemann U, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Folwaczny M, Mussack T, Klein W, Griga T, Maier K, Seiderer J, Wetzke M, Konrad A, Török H, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Brand S. rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PloS one 2007; 2:e819.
05.09.2007rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants
05.09.2007PloS one 2007; 2:e819
Glas Jürgen, Epplen Jörg T, Schiemann Uwe, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Müller-Myhsok Bertram, Folwaczny Matthias, Mussack Thomas, Klein Wolfram, Griga Thomas, Maier Kerstin, Seiderer Julia, Wetzke Martin, Konrad Astrid, Török Helga-Paula, Schmechel Silke, Tonenchi Laurian, Grassl Christine, Dambacher Julia, Pfennig Simone, Brand Stephan
SOCS1 silencing enhances antitumor activity of type I IFNs by regulating apoptosis in neuroendocrine tumor cells
Zitzmann K, Brand S, De Toni E, Baehs S, Göke B, Meinecke J, Spöttl G, Meyer H, Auernhammer C. SOCS1 silencing enhances antitumor activity of type I IFNs by regulating apoptosis in neuroendocrine tumor cells. Cancer Res 2007; 67:5025-32.
15.05.2007SOCS1 silencing enhances antitumor activity of type I IFNs by regulating apoptosis in neuroendocrine tumor cells
15.05.2007Cancer Res 2007; 67:5025-32
Zitzmann Kathrin, Brand Stephan, De Toni Enrico N, Baehs Sebastian, Göke Burkhard, Meinecke Jennifer, Spöttl Gerald, Meyer Heinrich H H D, Auernhammer Christoph J
Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease
Dambacher J, Beigel F, Seiderer J, Haller D, Göke B, Auernhammer C, Brand S. Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease. Gut 2007; 56:1257-65.
20.04.2007Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease
20.04.2007Gut 2007; 56:1257-65
Dambacher Julia, Beigel Florian, Seiderer Julia, Haller Dirk, Göke Burkhard, Auernhammer Christoph J, Brand Stephan
The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells
Zitzmann K, De Toni E, Brand S, Göke B, Meinecke J, Spöttl G, Meyer H, Auernhammer C. The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells. Neuroendocrinology 2007; 85:54-60.
19.02.2007The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells
19.02.2007Neuroendocrinology 2007; 85:54-60
Zitzmann Kathrin, De Toni Enrico N, Brand Stephan, Göke Burkhard, Meinecke Jennifer, Spöttl Gerald, Meyer Heinrich H D, Auernhammer Christoph J
IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro
Brand S, Thasler W, Bilzer M, Diepolder H, Göke B, Storr M, Steib C, Olszak T, Prüfer T, Weiss T, Heeg M, Zitzmann K, Beigel F, Dambacher J, Auernhammer C. IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro. Am J Physiol Gastrointest Liver Physiol 2007; 292:G1019-28.
04.01.2007IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro
04.01.2007Am J Physiol Gastrointest Liver Physiol 2007; 292:G1019-28
Brand Stephan, Thasler Wolfgang E, Bilzer Manfred, Diepolder Helmut, Göke Burkhard, Storr Martin, Steib Christian J, Olszak Torsten, Prüfer Thomas, Weiss Thomas S, Heeg Malte H J, Zitzmann Kathrin, Beigel Florian, Dambacher Julia, Auernhammer Christoph J
Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease
Dambacher J, Lohse P, Ochsenkühn T, Göke B, Diebold J, Otte J, Tillack C, Konrad A, Hofbauer K, Pfennig S, Schnitzler F, Sisic Z, Seiderer J, Staudinger T, Brand S. Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease. Inflamm Bowel Dis 2007; 13:71-82.
01.01.2007Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease
01.01.2007Inflamm Bowel Dis 2007; 13:71-82
Dambacher Julia, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Diebold Joachim, Otte Jan-Michel, Tillack Cornelia, Konrad Astrid, Hofbauer Katrin, Pfennig Simone, Schnitzler Fabian, Sisic Zeljka, Seiderer Julia, Staudinger Tanja, Brand Stephan
Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis
Seiderer J, Lohse P, Göke B, Sackmann M, Tillack C, Dambacher J, Hofbauer K, Herrmann K, Pfennig S, Staudinger T, Brand S, Schnitzler F, Ochsenkühn T. Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis. Scand J Gastroenterol 2006; 41:1421-32.
01.12.2006Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis
01.12.2006Scand J Gastroenterol 2006; 41:1421-32
Seiderer Julia, Lohse Peter, Göke Burkhard, Sackmann Michael, Tillack Cornelia, Dambacher Julia, Hofbauer Katrin, Herrmann Karin, Pfennig Simone, Staudinger Tanja, Brand Stephan, Schnitzler Fabian, Ochsenkühn Thomas
Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study
Seiderer J, Lohse P, Göke B, Schoenberg S, Pfennig S, Crispin A, Hatz R, Schnitzler F, Herrmann K, Brand S, Ochsenkühn T. Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study. Inflamm Bowel Dis 2006; 12:1114-21.
01.12.2006Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study
01.12.2006Inflamm Bowel Dis 2006; 12:1114-21
Seiderer Julia, Lohse Peter, Göke Burkhard, Schoenberg Stefan O, Pfennig Simone, Crispin Alexander, Hatz Rudolf, Schnitzler Fabian, Herrmann Karin A, Brand Stephan, Ochsenkühn Thomas
Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy
Seiderer J, Zech C, Diebold J, Schoenberg S, Brand S, Tillack C, Göke B, Ochsenkühn T. Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy. Eur J Gastroenterol Hepatol 2006; 18:553-5.
01.05.2006Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy
01.05.2006Eur J Gastroenterol Hepatol 2006; 18:553-5
Seiderer Julia, Zech Christoph J, Diebold Joachim, Schoenberg Stefan O, Brand Stephan, Tillack Cornelia, Göke Burkhard, Ochsenkühn Thomas
Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells
Zitzmann K, Brand S, Baehs S, Göke B, Meinecke J, Spöttl G, Meyer H, Auernhammer C. Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells. Biochem Biophys Res Commun 2006; 344:1334-41.
24.04.2006Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells
24.04.2006Biochem Biophys Res Commun 2006; 344:1334-41
Zitzmann Kathrin, Brand Stephan, Baehs Sebastian, Göke Burkhard, Meinecke Jennifer, Spöttl Gerald, Meyer Heinrich, Auernhammer Christoph J
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
Brand S, Auernhammer C, Göke B, Ochsenkühn T, Seiderer J, Herrmann K, Leclair S, Popp A, Jagla W, Marquardt A, Diepolder H, Otte J, Eichhorst S, Zitzmann K, Olszak T, Beigel F, Dambacher J. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol 2006; 290:G827-38.
01.04.2006IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
01.04.2006Am J Physiol Gastrointest Liver Physiol 2006; 290:G827-38
Brand Stephan, Auernhammer Christoph J, Göke Burkhard, Ochsenkühn Thomas, Seiderer Julia, Herrmann Karin, Leclair Stéphane, Popp Andreas, Jagla Wolfgang, Marquardt Andreas, Diepolder Helmut, Otte Jan-Michel, Eichhorst Sören T, Zitzmann Kathrin, Olszak Torsten, Beigel Florian, Dambacher Julia
Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells
Brand S, Olszak T, Beigel F, Diebold J, Otte J, Eichhorst S, Göke B, Dambacher J. Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells. J Cell Biochem 2006; 97:709-23.
01.03.2006Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells
01.03.2006J Cell Biochem 2006; 97:709-23
Brand Stephan, Olszak Torsten, Beigel Florian, Diebold Joachim, Otte Jan-Michel, Eichhorst Soeren T, Göke Burkhard, Dambacher Julia
Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease
Schnitzler F, Ochsenkühn T, Göke B, Tillack C, Seiderer J, Hofbauer K, Pfennig S, Staudinger T, Brand S, Lohse P. Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease. Immunogenetics 2006; 58:99-106.
17.02.2006Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease
17.02.2006Immunogenetics 2006; 58:99-106
Schnitzler Fabian, Ochsenkühn Thomas, Göke Burkhard, Tillack Cornelia, Seiderer Julia, Hofbauer Katrin, Pfennig Simone, Staudinger Tanja, Brand Stephan, Lohse Peter
Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype
Brand S, Ochsenkühn T, Göke B, Konrad A, Tillack C, Seiderer J, Pfennig S, Staudinger T, Schnitzler F, Dambacher J, Hofbauer K, Lohse P. Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype. Am J Gastroenterol 2006; 101:99-106.
01.01.2006Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype
01.01.2006Am J Gastroenterol 2006; 101:99-106
Brand Stephan, Ochsenkühn Thomas, Göke Burkhard, Konrad Astrid, Tillack Cornelia, Seiderer Julia, Pfennig Simone, Staudinger Tanja, Schnitzler Fabian, Dambacher Julia, Hofbauer Katrin, Lohse Peter
CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation
Brand S, Dambacher J, Beigel F, Olszak T, Diebold J, Otte J, Göke B, Eichhorst S. CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. Exp Cell Res 2005; 310:117-30.
15.10.2005CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation
15.10.2005Exp Cell Res 2005; 310:117-30
Brand Stephan, Dambacher Julia, Beigel Florian, Olszak Torsten, Diebold Joachim, Otte Jan-Michel, Göke Burkhard, Eichhorst Sören T
IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression
Brand S, Göke B, Auernhammer C, Adler B, Diepolder H, Diebold J, Otte J, Eichhorst S, Zitzmann K, Olszak T, Beigel F, Dambacher J. IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression. Am J Physiol Gastrointest Liver Physiol 2005; 289:G960-8.
28.07.2005IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression
28.07.2005Am J Physiol Gastrointest Liver Physiol 2005; 289:G960-8
Brand Stephan, Göke Burkhard, Auernhammer Christoph J, Adler Barbara, Diepolder Helmut, Diebold Joachim, Otte Jan-Michel, Eichhorst Sören T, Zitzmann Kathrin, Olszak Torsten, Beigel Florian, Dambacher Julia
The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease
Brand S, Lohse P, Göke B, Crispin A, Konrad A, Tillack C, Seiderer J, Dambacher J, Hofbauer K, Pfennig S, Schnitzler F, Staudinger T, Ochsenkühn T. The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease. Inflamm Bowel Dis 2005; 11:645-52.
01.07.2005The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease
01.07.2005Inflamm Bowel Dis 2005; 11:645-52
Brand Stephan, Lohse Peter, Göke Burkhard, Crispin Alexander, Konrad Astrid, Tillack Cornelia, Seiderer Julia, Dambacher Julia, Hofbauer Katrin, Pfennig Simone, Schnitzler Fabian, Staudinger Tanja, Ochsenkühn Thomas