Burkhard Göke
Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus
Diegelmann J, Beigel F, Zitzmann K, Kaul A, Göke B, Auernhammer C, Bartenschlager R, Diepolder H, Brand S. Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. PloS one 2010; 5:e15200.
08.12.2010Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus
08.12.2010PloS one 2010; 5:e15200
Diegelmann Julia, Beigel Florian, Zitzmann Kathrin, Kaul Artur, Göke Burkhard, Auernhammer Christoph J, Bartenschlager Ralf, Diepolder Helmut M, Brand Stephan
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Folwaczny M, Ochsenkühn T, Göke B, Weidinger M, Olszak T, Beigel F, Wetzke M, Pfennig S, Tengler B, Fischer D, Seiderer J, Brand S. Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1917-24.
03.12.2010Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
03.12.2010Inflamm Bowel Dis 2010; 17:1917-24
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Folwaczny Matthias, Ochsenkühn Thomas, Göke Burkhard, Weidinger Maria, Olszak Torsten, Beigel Florian, Wetzke Martin, Pfennig Simone, Tengler Barbara, Fischer Daniel, Seiderer Julia, Brand Stephan
Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation
Diegelmann J, Seiderer J, Niess J, Haller D, Göke B, Reinecker H, Brand S. Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation. Inflamm Bowel Dis 2010; 16:1871-81.
01.11.2010Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation
01.11.2010Inflamm Bowel Dis 2010; 16:1871-81
Diegelmann Julia, Seiderer Julia, Niess Jan-Hendrik, Haller Dirk, Göke Burkhard, Reinecker Hans-Christian, Brand Stephan
Safety of adalimumab in Crohn's disease during pregnancy: case report and review of the literature
Jürgens M, Ochsenkühn T, Göke B, Tillack C, Beigel F, Hasbargen U, Hübener C, Filik L, Brand S, Seiderer J. Safety of adalimumab in Crohn's disease during pregnancy: case report and review of the literature. Inflamm Bowel Dis 2010; 16:1634-6.
01.10.2010Safety of adalimumab in Crohn's disease during pregnancy: case report and review of the literature
01.10.2010Inflamm Bowel Dis 2010; 16:1634-6
Jürgens Matthias, Ochsenkühn Thomas, Göke Burkhard, Tillack Cornelia, Beigel Florian, Hasbargen Uwe, Hübener Christoph, Filik Levent, Brand Stephan, Seiderer Julia
Role of PPARG gene variants in inflammatory bowel disease
Glas J, Roeske D, Diegelmann J, Müller-Myhsok B, Ochsenkühn T, Göke B, Paschos E, Wetzke M, Pfennig S, Markus C, Seiderer J, Brand S. Role of PPARG gene variants in inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1057-8.
18.08.2010Role of PPARG gene variants in inflammatory bowel disease
18.08.2010Inflamm Bowel Dis 2010; 17:1057-8
Glas Jürgen, Roeske Darina, Diegelmann Julia, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Paschos Ekaterini, Wetzke Martin, Pfennig Simone, Markus Christian, Seiderer Julia, Brand Stephan
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset
Glas J, Roeske D, Müller-Myhsok B, Diegelmann J, Ochsenkühn T, Göke B, Folwaczny M, Lohse P, Epplen J, Klein W, Pfennig S, Weidinger M, Beigel F, Fries C, Nagy M, Seiderer J, Brand S. Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. PloS one 2010; 5:e10373.
29.04.2010Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset
29.04.2010PloS one 2010; 5:e10373
Glas Jürgen, Roeske Darina, Müller-Myhsok Bertram, Diegelmann Julia, Ochsenkühn Thomas, Göke Burkhard, Folwaczny Matthias, Lohse Peter, Epplen Jörg T, Klein Wolfram, Pfennig Simone, Weidinger Maria, Beigel Florian, Fries Christoph, Nagy Melinda, Seiderer Julia, Brand Stephan
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
Jürgens M, Herrmann K, Lohse P, Göke B, Kreis M, Schnitzler F, Weidinger M, Beigel F, Tillack C, Pfennig S, Wagner J, Wetzke M, Glas J, Seiderer J, Laubender R, Brand S, Ochsenkühn T. The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype. J Gastroenterol 2010; 45:721-31.
29.04.2010The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
29.04.2010J Gastroenterol 2010; 45:721-31
Jürgens Matthias, Herrmann Karin, Lohse Peter, Göke Burkhard, Kreis Martin E, Schnitzler Fabian, Weidinger Maria, Beigel Florian, Tillack Cornelia, Pfennig Simone, Wagner Johanna, Wetzke Martin, Glas Jürgen, Seiderer Julia, Laubender Rüdiger P, Brand Stephan, Ochsenkühn Thomas
Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease
Zitzmann K, Rüden J, Brand S, Göke B, Lichtl J, Spöttl G, Auernhammer C. Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease. Cancer Lett 2010; 295:100-9.
30.03.2010Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease
30.03.2010Cancer Lett 2010; 295:100-9
Zitzmann Kathrin, Rüden Janina von, Brand Stephan, Göke Burkhard, Lichtl Jennifer, Spöttl Gerald, Auernhammer Christoph J
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
Jürgens M, Ochsenkühn T, Glas J, Göke B, Lohse P, Tillack C, Schnitzler F, Stallhofer J, Pfennig S, Beigel F, Wetzke M, Wagner J, Seiderer J, Weidinger M, Hartl F, Laubender R, Brand S. Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. Am J Gastroenterol 2010; 105:1811-9.
02.03.2010Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
02.03.2010Am J Gastroenterol 2010; 105:1811-9
Jürgens Matthias, Ochsenkühn Thomas, Glas Jürgen, Göke Burkhard, Lohse Peter, Tillack Cornelia, Schnitzler Fabian, Stallhofer Johannes, Pfennig Simone, Beigel Florian, Wetzke Martin, Wagner Johanna, Seiderer Julia, Weidinger Maria, Hartl Franziska, Laubender Rüdiger P, Brand Stephan
The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease
Storr M, Emmerdinger D, Diegelmann J, Pfennig S, Ochsenkühn T, Göke B, Lohse P, Brand S. The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. PloS one 2010; 5:e9453.
26.02.2010The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease
26.02.2010PloS one 2010; 5:e9453
Storr Martin, Emmerdinger Dominik, Diegelmann Julia, Pfennig Simone, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Brand Stephan
Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease
Beigel F, Jürgens M, Filik L, Bader L, Lück C, Göke B, Ochsenkühn T, Brand S, Seiderer J. Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease. Inflamm Bowel Dis 2009; 15:1240-4.
01.08.2009Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease
01.08.2009Inflamm Bowel Dis 2009; 15:1240-4
Beigel Florian, Jürgens Matthias, Filik Levent, Bader Lutz, Lück Christian, Göke Burkhard, Ochsenkühn Thomas, Brand Stephan, Seiderer Julia
Hepatosplenic T-cell lymphoma in a patient with Crohn's disease
Beigel F, Jürgens M, Tillack C, Subklewe M, Mayr D, Göke B, Brand S, Ochsenkühn T. Hepatosplenic T-cell lymphoma in a patient with Crohn's disease. Nat Rev Gastroenterol Hepatol 2009; 6:433-6.
01.07.2009Hepatosplenic T-cell lymphoma in a patient with Crohn's disease
01.07.2009Nat Rev Gastroenterol Hepatol 2009; 6:433-6
Beigel Florian, Jürgens Matthias, Tillack Cornelia, Subklewe Marion, Mayr Doris, Göke Burkhard, Brand Stephan, Ochsenkühn Thomas
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
Török H, Müller-Myhsok B, Folwaczny C, Göke B, Folwaczny M, Ochsenkühn T, Lohse P, Klein W, Wetzke M, Teshome M, Tonenchi L, Endres I, Glas J, Brand S. Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol 2009; 104:1723-33.
19.05.2009Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
19.05.2009Am J Gastroenterol 2009; 104:1723-33
Török Helga P, Müller-Myhsok Bertram, Folwaczny Christian, Göke Burkhard, Folwaczny Matthias, Ochsenkühn Thomas, Lohse Peter, Klein Wolfram, Wetzke Martin, Teshome Molla Y, Tonenchi Laurian, Endres Ilona, Glas Jürgen, Brand Stephan
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
Glas J, Müller-Myhsok B, Ochsenkühn T, Göke B, Lohse P, Folwaczny M, Koletzko S, Lacher M, Schiemann U, Griga T, Epplen J, Klein W, Pfennig S, Wetzke M, Ripke S, Stallhofer J, Brand S. Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol 2009; 104:1737-44.
19.05.2009Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
19.05.2009Am J Gastroenterol 2009; 104:1737-44
Glas Jürgen, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Folwaczny Matthias, Koletzko Sibylle, Lacher Martin, Schiemann Uwe, Griga Thomas, Epplen Jörg T, Klein Wolfram, Pfennig Simone, Wetzke Martin, Ripke Stephan, Stallhofer Johannes, Brand Stephan
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
Glas J, Klein W, Epplen J, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Griga T, Jürgens M, Stallhofer J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török H, Brand S. rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2009; 104:665-72.
03.02.2009rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
03.02.2009Am J Gastroenterol 2009; 104:665-72
Glas Jürgen, Klein Wolfram, Epplen Jörg T, Schiemann Uwe, Mussack Thomas, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Griga Thomas, Jürgens Matthias, Stallhofer Johannes, Seiderer Julia, Pasciuto Giulia, Tillack Cornelia, Diegelmann Julia, Pfennig Simone, Konrad Astrid, Schmechel Silke, Wetzke Martin, Török Helga-Paula, Brand Stephan
Correlation of magnetic resonance enteroclysis (MRE) and wireless capsule endoscopy (CE) in the diagnosis of small bowel lesions in Crohn's disease
Tillack C, Seiderer J, Brand S, Göke B, Reiser M, Schaefer C, Diepolder H, Ochsenkühn T, Herrmann K. Correlation of magnetic resonance enteroclysis (MRE) and wireless capsule endoscopy (CE) in the diagnosis of small bowel lesions in Crohn's disease. Inflamm Bowel Dis 2008; 14:1219-28.
01.09.2008Correlation of magnetic resonance enteroclysis (MRE) and wireless capsule endoscopy (CE) in the diagnosis of small bowel lesions in Crohn's disease
01.09.2008Inflamm Bowel Dis 2008; 14:1219-28
Tillack Cornelia, Seiderer Julia, Brand Stephan, Göke Burkhard, Reiser Maximilian F, Schaefer Claus, Diepolder Helmut, Ochsenkühn Thomas, Herrmann Karin A
Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors
Storr M, Patel K, Brand S, Göke B, Lutz B, Buckley N, Massa F, Sibaev A, Yüce B, Zhang H, Emmerdinger D, Keenan C, Sharkey K. Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors. J Mol Med 2008; 86:925-36.
21.05.2008Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors
21.05.2008J Mol Med 2008; 86:925-36
Storr Martin A, Patel Kamala D, Brand Stephan, Göke Burkhard, Lutz Beat, Buckley Nancy E, Massa Federico, Sibaev Andrei, Yüce Birol, Zhang Hong, Emmerdinger Dominik, Keenan Catherine M, Sharkey Keith A
Free fatty acids sensitize hepatocytes to bile acid-induced apoptosis
Pusl T, Wild N, Vennegeerts T, Wimmer R, Göke B, Brand S, Rust C. Free fatty acids sensitize hepatocytes to bile acid-induced apoptosis. Biochem Biophys Res Commun 2008; 371:441-5.
29.04.2008Free fatty acids sensitize hepatocytes to bile acid-induced apoptosis
29.04.2008Biochem Biophys Res Commun 2008; 371:441-5
Pusl Thomas, Wild Nadine, Vennegeerts Timo, Wimmer Ralf, Göke Burkhard, Brand Stephan, Rust Christian
Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD
Seiderer J, Lohse P, Müller-Myhsok B, Ochsenkühn T, Göke B, Konrad A, Schmechel S, Jürgens M, Pfennig S, Tillack C, Stallhofer J, Glas J, Diegelmann J, Elben I, Brand S. Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD. Inflamm Bowel Dis 2008; 14:437-45.
01.04.2008Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD
01.04.2008Inflamm Bowel Dis 2008; 14:437-45
Seiderer Julia, Lohse Peter, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Konrad Astrid, Schmechel Silke, Jürgens Matthias, Pfennig Simone, Tillack Cornelia, Stallhofer Johannes, Glas Jürgen, Diegelmann Julia, Elben Ira, Brand Stephan
Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status
Schmechel S, Konrad A, Diegelmann J, Glas J, Wetzke M, Paschos E, Lohse P, Göke B, Brand S. Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflamm Bowel Dis 2008; 14:204-12.
01.02.2008Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status
01.02.2008Inflamm Bowel Dis 2008; 14:204-12
Schmechel Silke, Konrad Astrid, Diegelmann Julia, Glas Jürgen, Wetzke Martin, Paschos Ekaterini, Lohse Peter, Göke Burkhard, Brand Stephan