Tobias Sinnberg
Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade.
Wyss N, Berner F, Walter V, Jochum A, Purde M, Abdou M, Sinnberg T, Hofmeister K, Pop O, Hasan A, Bauer J, Cheng H, Lütge M, Klümper N, Diem S, Kosaloglu-Yalcin Z, Zhang Y, Sellmer L, Macek B, Karbach J, König D, Läubli H, Zender L, Meyer B, Driessen C, Schürch C, Jochum W, Amaral T, Heinzerling L, Cozzio A, Hegazy A, Schneider T, Brutsche M, Sette A, Lenz T, Walz J, Rammensee H, Früh M, Jäger E, Becher B, Tufman A, Núñez N, Jörger M, Flatz L. Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade. Am J Respir Crit Care Med 2024; 210:919-930.
01.10.2024Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade.
01.10.2024Am J Respir Crit Care Med 2024; 210:919-930
Wyss Nina, Berner Fiamma, Walter Vincent, Jochum Ann-Kristin, Purde Mette T, Abdou Marie-Therese, Sinnberg Tobias, Hofmeister Kathrin, Pop Oltin, Hasan Ali, Bauer Jens, Cheng Hung-Wei, Lütge Mechthild, Klümper Niklas, Diem Stefan, Kosaloglu-Yalcin Zeynep, Zhang Yizheng, Sellmer Laura, Macek Boris, Karbach Julia, König David, Läubli Heinz, Zender Lars, Meyer Britta S, Driessen Christoph, Schürch Christian M, Jochum Wolfram, Amaral Teresa, Heinzerling Lucie M, Cozzio Antonio, Hegazy AhN, Schneider Tino, Brutsche Martin, Sette Alessandro, Lenz Tobias L, Walz Juliane Sarah, Rammensee Hans-Georg, Früh Martin, Jäger Elke, Becher Burkhard, Tufman Amanda, Núñez Nicolás Gonzalo, Jörger Markus, Flatz Lukas
Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
Lichtensteiger C, Koblischke M, Berner F, Jochum A, Sinnberg T, Balciunaite B, Purde M, Walter V, Abdou M, Hofmeister K, Kohler P, Vernazza P, Albrich W, Kahlert C, Zoufaly A, Traugott M, Kern L, Pietsch U, Kleger G, Filipovic M, Kneilling M, Cozzio A, Pop O, Bomze D, Bergthaler A, Hasan A, Aberle J, Flatz L. Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients. J Autoimmun 2023; 140:103118.
10.10.2023Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
10.10.2023J Autoimmun 2023; 140:103118
Lichtensteiger Christa, Koblischke Maximilian, Berner Fiamma, Jochum Ann-Kristin, Sinnberg Tobias, Balciunaite Beatrice, Purde Mette-Triin, Walter Vincent, Abdou Marie-Therese, Hofmeister Kathrin, Kohler Philipp, Vernazza Pietro L, Albrich Werner, Kahlert Christian, Zoufaly Alexander, Traugott Marianna T, Kern Lukas, Pietsch Urs, Kleger Gian-Reto, Filipovic Miodrag, Kneilling Manfred, Cozzio Antonio, Pop Oltin, Bomze David, Bergthaler Andreas, Hasan Ali, Aberle Judith, Flatz Lukas
EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy.
Amaral T, Pop O, Chatziioannou E, Sinnberg T, Niessner H, Zhao J, Ring S, Jörger M, Schroeder C, Armeanu-Ebinger S, Cozzio A, Leiter U, Thomas I, Jochum W, Garbe C, Forchhammer S, Levesque M, Mangana J, Hölzel M, Dummer R, Schürch C, Forschner A, Flatz L. EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy. J Am Acad Dermatol 2023; 89:1072-1074.
22.07.2023EGFR expression is associated with relapse in a melanoma cohort receiving adjuvant PD-1-based immunotherapy.
22.07.2023J Am Acad Dermatol 2023; 89:1072-1074
Amaral Teresa, Pop Oltin Tiberiu, Chatziioannou Eftychia, Sinnberg Tobias, Niessner Heike, Zhao Jing Hua, Ring Sandra Stephanie, Jörger Markus, Schroeder Christopher, Armeanu-Ebinger Sorin, Cozzio Antonio, Leiter Ulrike, Thomas Ioannis, Jochum Wolfram, Garbe Claus, Forchhammer Stephan, Levesque Mitchell Paul, Mangana Joanna, Hölzel Michael, Dummer Reinhard, Schürch Christian M, Forschner Andrea, Flatz Lukas
Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases.
Chatziioannou E, Roßner J, Aung T, Rimm D, Niessner H, Keim U, Serna-Higuita L, Bonzheim I, Kuhn Cuellar L, Westphal D, Steininger J, Meier F, Pop O, Forchhammer S, Flatz L, Eigentler T, Garbe C, Röcken M, Amaral T, Sinnberg T. Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases. EBioMedicine 2023; 93:104644.
07.06.2023Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases.
07.06.2023EBioMedicine 2023; 93:104644
Chatziioannou Eftychia, Roßner Jana, Aung Thazin New, Rimm David L, Niessner Heike, Keim Ulrike, Serna-Higuita Lina María, Bonzheim Irina, Kuhn Cuellar Luis, Westphal Dana, Steininger Julian, Meier Friedegund, Pop Oltin Tiberiu, Forchhammer Stephan, Flatz Lukas, Eigentler Thomas Kurt, Garbe Claus, Röcken Martin, Amaral Teresa, Sinnberg Tobias
Features and Long-Term Outcomes of Stage IV Melanoma Patients Achieving Complete Response Under Anti-PD-1-Based Immunotherapy.
Chatziioannou E, Leiter U, Thomas I, Keim U, Seeber O, Meiwes A, Boessenecker I, Gonzalez S, Torres F, Niessner H, Sinnberg T, Forschner A, Flatz L, Amaral T. Features and Long-Term Outcomes of Stage IV Melanoma Patients Achieving Complete Response Under Anti-PD-1-Based Immunotherapy. Am J Clin Dermatol 2023; 24:453-467.
04.05.2023Features and Long-Term Outcomes of Stage IV Melanoma Patients Achieving Complete Response Under Anti-PD-1-Based Immunotherapy.
04.05.2023Am J Clin Dermatol 2023; 24:453-467
Chatziioannou Eftychia, Leiter Ulrike, Thomas Ioannis, Keim Ulrike, Seeber Olivia, Meiwes Andreas, Boessenecker Isabell, Gonzalez Stephanie Sanchez, Torres Francisco Merraz, Niessner Heike, Sinnberg Tobias, Forschner Andrea, Flatz Lukas, Amaral Teresa
Successful treatment of metastatic uveal melanoma with ipilimumab and nivolumab after severe progression under tebentafusp: a case report.
Reiter S, Schroeder C, Broche J, Sinnberg T, Bonzheim I, Süsskind D, Flatz L, Forschner A. Successful treatment of metastatic uveal melanoma with ipilimumab and nivolumab after severe progression under tebentafusp: a case report. Front Oncol 2023; 13:1167791.
03.05.2023Successful treatment of metastatic uveal melanoma with ipilimumab and nivolumab after severe progression under tebentafusp: a case report.
03.05.2023Front Oncol 2023; 13:1167791
Reiter Selina, Schroeder Christopher, Broche Julian, Sinnberg Tobias, Bonzheim Irina, Süsskind Daniela, Flatz Lukas, Forschner Andrea
Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19.
Sinnberg T, Lichtensteiger C, Ali O, Pop O, Risch L, Brugger S, Velic A, Bomze D, Kohler P, Vernazza P, Albrich W, Kahlert C, Abdou M, Wyss N, Hofmeister K, Niessner H, Zinner C, Gilardi M, Tzankov A, Röcken M, Dulovic A, Shambat S, Ruetalo N, Buehler P, Scheier T, Jochum W, Kern L, Henz S, Schneider T, Kuster G, Lampart M, Siegemund M, Bingisser R, Schindler M, Schneiderhan-Marra N, Kalbacher H, McCoy K, Spengler W, Brutsche M, Macek B, Twerenbold R, Penninger J, Matter M, Flatz L, Jochum A. Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19. Am J Respir Crit Care Med 2023; 207:38-49.
01.01.2023Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19.
01.01.2023Am J Respir Crit Care Med 2023; 207:38-49
Sinnberg Tobias, Lichtensteiger Christa, Ali Omar Hasan, Pop Oltin T, Risch Lorenz, Brugger Silvio D, Velic Ana, Bomze David, Kohler Philipp, Vernazza Pietro, Albrich Werner, Kahlert Christian, Abdou Marie-Therese, Wyss Nina, Hofmeister Kathrin, Niessner Heike, Zinner Carl, Gilardi Mara, Tzankov Alexandar, Röcken Martin, Dulovic Alex, Shambat Srikanth Mairpady, Ruetalo Natalia, Buehler Philipp K, Scheier Thomas C, Jochum Wolfram, Kern Lukas, Henz Samuel, Schneider Tino, Kuster Gabriela M, Lampart Maurin, Siegemund Martin, Bingisser Roland, Schindler Michael, Schneiderhan-Marra Nicole, Kalbacher Hubert, McCoy Kathy D, Spengler Werner, Brutsche Martin H, Macek Boris, Twerenbold Raphael, Penninger Josef M, Matter Matthias S, Flatz Lukas, Jochum Ann-Kristin
Identification of stage I/II melanoma patients at high risk for recurrence using a model combining clinicopathologic factors with gene expression profiling (CP-GEP).
Amaral T, Sinnberg T, Chatziioannou E, Niessner H, Leiter U, Keim U, Forschner A, Dwarkasing J, Tjien-Fooh F, Wever R, Flatz L, Eggermont A, Forchhammer S. Identification of stage I/II melanoma patients at high risk for recurrence using a model combining clinicopathologic factors with gene expression profiling (CP-GEP). Eur J Cancer 2022; 182:155-162.
30.12.2022Identification of stage I/II melanoma patients at high risk for recurrence using a model combining clinicopathologic factors with gene expression profiling (CP-GEP).
30.12.2022Eur J Cancer 2022; 182:155-162
Amaral Teresa, Sinnberg Tobias, Chatziioannou Eftychia, Niessner Heike, Leiter Ulrike, Keim Ulrike, Forschner Andrea, Dwarkasing Jvalini, Tjien-Fooh Félicia, Wever Renske, Flatz Lukas, Eggermont Alexander, Forchhammer Stephan
Autoreactive napsin A-specific T cells are enriched in lung tumors and inflammatory lung lesions during immune checkpoint blockade.
Berner F, Bomze D, Lichtensteiger C, Walter V, Niederer R, Hasan Ali O, Wyss N, Bauer J, Freudenmann L, Marcu A, Wolfschmitt E, Haen S, Gross T, Abdou M, Diem S, Knöpfli S, Sinnberg T, Hofmeister K, Cheng H, Toma M, Klümper N, Purde M, Pop O, Jochum A, Pascolo S, Jörger M, Früh M, Jochum W, Rammensee H, Läubli H, Hölzel M, Neefjes J, Walz J, Flatz L. Autoreactive napsin A-specific T cells are enriched in lung tumors and inflammatory lung lesions during immune checkpoint blockade. Sci Immunol 2022; 7:eabn9644.
02.09.2022Autoreactive napsin A-specific T cells are enriched in lung tumors and inflammatory lung lesions during immune checkpoint blockade.
02.09.2022Sci Immunol 2022; 7:eabn9644
Berner Fiamma, Bomze David, Lichtensteiger Christa, Walter Vincent, Niederer Rebekka, Hasan Ali Omar, Wyss Nina, Bauer Jens, Freudenmann Lena Katharina, Marcu Ana, Wolfschmitt Eva-Maria, Haen Sebastian, Gross Thorben, Abdou Marie-Therese, Diem Stefan, Knöpfli Stella, Sinnberg Tobias, Hofmeister Kathrin, Cheng Hung-Wei, Toma Marieta, Klümper Niklas, Purde Mette-Triin, Pop Oltin Tiberiu, Jochum Ann-Kristin, Pascolo Steve, Jörger Markus, Früh Martin, Jochum Wolfram, Rammensee Hans-Georg, Läubli Heinz, Hölzel Michael, Neefjes Jacques, Walz Juliane, Flatz Lukas
Vitamin C Deficiency in Blood Samples of COVID-19 Patients.
Sinnberg T, Lichtensteiger C, Hill-Mündel K, Leischner C, Niessner H, Busch C, Renner O, Wyss N, Flatz L, Lauer U, Hoelzle L, Nohr D, Burkard M, Marongiu L, Venturelli S. Vitamin C Deficiency in Blood Samples of COVID-19 Patients. Antioxidants (Basel) 2022; 11
15.08.2022Vitamin C Deficiency in Blood Samples of COVID-19 Patients.
15.08.2022Antioxidants (Basel) 2022; 11
Sinnberg Tobias, Lichtensteiger Christa, Hill-Mündel Katharina, Leischner Christian, Niessner Heike, Busch Christian, Renner Olga, Wyss Nina, Flatz Lukas, Lauer Ulrich M, Hoelzle Ludwig E, Nohr Donatus, Burkard Markus, Marongiu Luigi, Venturelli Sascha
Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy
Bochem J, Meier F, Terheyden P, Königsrainer A, Garbe C, Flatz L, Pawelec G, Eigentler T, Löffler M, Weide B, Niessner H, Sinnberg T, Zelba H, Spreuer J, Amaral T, Gaissler A, Pop O, Thiel K, Yurttas C, Soffel D, Forchhammer S, Wistuba-Hamprecht K. Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy. J Immunother Cancer 2021; 9
01.01.2021Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy
01.01.2021J Immunother Cancer 2021; 9
Bochem Jonas, Meier Friedegund, Terheyden Patrick, Königsrainer Alfred, Garbe Claus, Flatz Lukas, Pawelec Graham, Eigentler Thomas K, Löffler Markus W, Weide Benjamin, Niessner Heike, Sinnberg Tobias, Zelba Henning, Spreuer Janine, Amaral Teresa, Gaissler Andrea, Pop Oltin, Thiel Karolin, Yurttas Can, Soffel Daniel, Forchhammer Stephan, Wistuba-Hamprecht Kilian
Expression of DNA Methyltransferase 1 Is a Hallmark of Melanoma, Correlating with Proliferation and Response to B-Raf and Mitogen-Activated Protein Kinase Inhibition in Melanocytic Tumors
Gassenmaier M, Garbe C, Schaller M, Wagner N, Bösmüller H, Niessner H, Sinnberg T, Kosnopfel C, Ikenberg K, Eigentler T, Fehrenbacher B, Rentschler M, Röcken M. Expression of DNA Methyltransferase 1 Is a Hallmark of Melanoma, Correlating with Proliferation and Response to B-Raf and Mitogen-Activated Protein Kinase Inhibition in Melanocytic Tumors. Am J Pathol 2020; 190:2155-2164.
15.07.2020Expression of DNA Methyltransferase 1 Is a Hallmark of Melanoma, Correlating with Proliferation and Response to B-Raf and Mitogen-Activated Protein Kinase Inhibition in Melanocytic Tumors
15.07.2020Am J Pathol 2020; 190:2155-2164
Gassenmaier Maximilian, Garbe Claus, Schaller Martin, Wagner Nikolaus, Bösmüller Hans, Niessner Heike, Sinnberg Tobias, Kosnopfel Corinna, Ikenberg Kristian, Eigentler Thomas K, Fehrenbacher Birgit, Rentschler Maximilian, Röcken Martin