Cristina Gil Cruz
wissenschaftliche(r) Mitarbeiter/in
Institut für Immunbiologie · Dept. Direktion
Cardiac Fibroblastic Niches in Homeostasis and Inflammation.
Cadosch N, Gil Cruz C, Pérez Shibayama C, Ludewig B. Cardiac Fibroblastic Niches in Homeostasis and Inflammation. Circ Res 2024; 134:1703-1717.
06.06.2024Cardiac Fibroblastic Niches in Homeostasis and Inflammation.
06.06.2024Circ Res 2024; 134:1703-1717
Cadosch Nadine, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Ludewig Burkhard
Bone morphogenic protein-4 availability in the cardiac microenviroment controls inflammation and fibrosis in autoimmune myocarditis
Pérez Shibayama C, Gil Cruz C, Cadosch N, Lütge M, Cheng H, De Martin A, Frischmann K, Joachimbauer A, Onder L, Papadopoulou I, Papadopoulou C, Ring S, Krebs P, P. Vu V, P. Nägele M, Rosi V, Parianos D, Zsilavecz V, Cooper L, Flammer A, Ruschitzka F, Reiner P, Schmidt D, Ludewig B. Bone morphogenic protein-4 availability in the cardiac microenviroment controls inflammation and fibrosis in autoimmune myocarditis. Nature Cardiovascular Research 2024; volume 3:301-316.
19.04.2024Bone morphogenic protein-4 availability in the cardiac microenviroment controls inflammation and fibrosis in autoimmune myocarditis
19.04.2024Nature Cardiovascular Research 2024; volume 3:301-316
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Cadosch Nadine, Lütge Mechthild, Cheng Hung-Wei, De Martin Angelina, Frischmann Kira, Joachimbauer Anna, Onder Lucas, Papadopoulou Iliana, Papadopoulou Chrysa, Ring Sandra, Krebs Philippe, P. Vu Vivian, P. Nägele Matthias, Rosi Valentina, Parianos Danae, Zsilavecz Valentin W, Cooper Leslie T., Flammer Andreas, Ruschitzka Frank, Reiner Peter P, Schmidt Dörthe, Ludewig Burkhard
Conserved stromal-immune cell circuits secure B cell homeostasis and function.
Lütge M, De Martin A, Gil Cruz C, Pérez Shibayama C, Stanossek Y, Onder L, Cheng H, Kurz L, Cadosch N, Soneson C, Robinson M, Stöckli S, Ludewig B, Pikor N. Conserved stromal-immune cell circuits secure B cell homeostasis and function. Nat Immunol 2023
18.05.2023Conserved stromal-immune cell circuits secure B cell homeostasis and function.
18.05.2023Nat Immunol 2023
Lütge Mechthild, De Martin Angelina, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Stanossek Yves, Onder Lucas, Cheng Hung-Wei, Kurz Lisa, Cadosch Nadine, Soneson Charlotte, Robinson Mark D, Stöckli Sandro, Ludewig Burkhard, Pikor Natalia
Fibroblasts tune myocardial inflammation and remodeling
Pérez Shibayama C, Gil Cruz C, Ludewig B. Fibroblasts tune myocardial inflammation and remodeling. Nature Cardiovascular Research 2022; 1:694–695.
12.08.2022Fibroblasts tune myocardial inflammation and remodeling
12.08.2022Nature Cardiovascular Research 2022; 1:694–695
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Ludewig Burkhard
Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function
Cheng H, Scandella E, Hehlgans T, Pérez Shibayama C, Gil Cruz C, Novkovic M, Onder L, Engetschwiler C, Lütge M, Mörbe U, Ludewig B. Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function. Nat Commun 2022; 13:2027.
19.04.2022Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function
19.04.2022Nat Commun 2022; 13:2027
Cheng Hung-Wei, Scandella Elke, Hehlgans T, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Novkovic M, Onder Lucas, Engetschwiler Céline, Lütge Mechthild, Mörbe Urs, Ludewig Burkhard
Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment
Ring S, Spiegl M, Besse A, Bonilla W, Stemeseder F, Schmidt S, Orlinger K, Krebs P, Ludewig B, Wenger R, Hartmann F, Cupovic J, Onder L, Lütge M, Pérez Shibayama C, Gil Cruz C, Scandella E, De Martin A, Mörbe U, Flatz L. Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment. Nat Commun 2021; 12:4734.
05.08.2021Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment
05.08.2021Nat Commun 2021; 12:4734
Ring Sandra, Spiegl Matthias, Besse Andrej, Bonilla Weldy V, Stemeseder Felix, Schmidt Sarah, Orlinger Klaus K, Krebs Philippe, Ludewig Burkhard, Wenger Robert, Hartmann Fabienne, Cupovic Jovana, Onder Lucas, Lütge Mechthild, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Scandella Elke, De Martin Angelina, Mörbe Urs, Flatz Lukas
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity
Prados A, Ludewig B, Koliaraki V, Pérez Shibayama C, Gil Cruz C, Lütge M, Mörbe U, Cheng H, Onder L, Kollias G. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol 2021; 22:510-519.
11.03.2021Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity
11.03.2021Nat Immunol 2021; 22:510-519
Prados Alejandro, Ludewig Burkhard, Koliaraki Vasiliki, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Lütge Mechthild, Mörbe Urs, Cheng Hung-Wei, Onder Lucas, Kollias George
Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
Pérez Shibayama C, Gil Cruz C, Colston J, Novkovic M, De Martin A, Ring S, Onder L, Cheng H, Lütge M, Islander U, Ludewig B. Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells. Sci Immunol 2020; 5
11.09.2020Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
11.09.2020Sci Immunol 2020; 5
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Colston Julia, Novkovic Mario, De Martin Angelina, Ring Sandra, Onder Lucas, Cheng Hung-Wei, Lütge Mechthild, Islander Ulrika, Ludewig Burkhard
Remodeling of light and dark zone follicular dendritic cells governs germinal center responses
Pikor N, Onder L, Linterman M, Nagasawa T, Nombela-Arrieta C, Cheng H, Novkovic M, Pérez Shibayama C, Gil Cruz C, Lütge M, Mörbe U, Ludewig B. Remodeling of light and dark zone follicular dendritic cells governs germinal center responses. Nat Immunol 2020; 21:649-659.
18.05.2020Remodeling of light and dark zone follicular dendritic cells governs germinal center responses
18.05.2020Nat Immunol 2020; 21:649-659
Pikor Natalia, Onder Lucas, Linterman Michelle A, Nagasawa Takashi, Nombela-Arrieta César, Cheng Hung-Wei, Novkovic Mario, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Lütge Mechthild, Mörbe Urs, Ludewig Burkhard
Conservation of the OmpC Porin Among Typhoidal and Non-Typhoidal Serovars
Valero-Pacheco N, Klenerman P, Reyes-Sandoval A, Isibasi A, Pastelin-Palacios R, Sánchez-Torres L, Gil Cruz C, Pérez Shibayama C, Kurioka A, Wong-Baeza I, Pérez-Toledo M, Kemlo P, Aldapa-Vega G, Blight J, López-Macías C. Conservation of the OmpC Porin Among Typhoidal and Non-Typhoidal Serovars. Front Immunol 2020; 10:2966.
09.01.2020Conservation of the OmpC Porin Among Typhoidal and Non-Typhoidal Serovars
09.01.2020Front Immunol 2020; 10:2966
Valero-Pacheco Nuriban, Klenerman Paul, Reyes-Sandoval Arturo, Isibasi Armando, Pastelin-Palacios Rodolfo, Sánchez-Torres Luvia E, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Kurioka Ayako, Wong-Baeza Isabel, Pérez-Toledo Marisol, Kemlo Phillip, Aldapa-Vega Gustavo, Blight Joshua, López-Macías Constantino
Heart non-specific effector CD4 T cells protect from postinflammatory fibrosis and cardiac dysfunction in experimental autoimmune myocarditis
Zarak-Crnkovic M, Eriksson U, Klingel K, Lüscher T, Distler O, Ludewig B, Westermann D, Bachmann M, Gil Cruz C, Lindner D, Vdovenko D, Müller-Edenborn B, Czyż J, Wijnen W, Czepiel M, Jaźwa-Kusior A, Kania G, Błyszczuk P. Heart non-specific effector CD4 T cells protect from postinflammatory fibrosis and cardiac dysfunction in experimental autoimmune myocarditis. Basic Res Cardiol 2019; 115:6.
20.12.2019Heart non-specific effector CD4 T cells protect from postinflammatory fibrosis and cardiac dysfunction in experimental autoimmune myocarditis
20.12.2019Basic Res Cardiol 2019; 115:6
Zarak-Crnkovic Martina, Eriksson Urs, Klingel Karin, Lüscher Thomas F, Distler Oliver, Ludewig Burkhard, Westermann Dirk, Bachmann Marta, Gil Cruz Cristina, Lindner Diana, Vdovenko Daria, Müller-Edenborn Björn, Czyż Jarosław, Wijnen Winandus J, Czepiel Marcin, Jaźwa-Kusior Agnieszka, Kania Gabriela, Błyszczuk Przemysław
Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
Gil Cruz C, Jahns R, Wyss M, Mooser C, Lambrecht B, Maeder M, Rickli H, Flatz L, Eriksson U, Geuking M, McCoy K, Boivin-Jahns V, Slack E, Arnoldini M, Pérez Shibayama C, De Martin A, Ronchi F, Van der Borght K, Niederer R, Onder L, Lütge M, Novkovic M, Nindl V, Ramos G, Ludewig B. Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy. Science 2019; 366:881-886.
15.11.2019Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
15.11.2019Science 2019; 366:881-886
Gil Cruz Cristina, Jahns Roland, Wyss Madeleine, Mooser Catherine, Lambrecht Bart N, Maeder Micha, Rickli Hans, Flatz Lukas, Eriksson Urs, Geuking Markus B, McCoy Kathy D, Boivin-Jahns Valérie, Slack Emma M C, Arnoldini Markus, Pérez Shibayama Christian Ivan, De Martin Angelina, Ronchi Francesca, Van der Borght Katrien, Niederer Rebekka, Onder Lucas, Lütge Mechthild, Novkovic Mario, Nindl Veronika, Ramos Gustavo, Ludewig Burkhard
Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses
Rieckmann M, van der Laan A, Piek J, Koch C, Wester H, Lapa C, Bauer W, Ludewig B, Friedman N, Frantz S, Hofmann U, Krijnen P, Niessen H, Delgobo M, Gaal C, Büchner L, Steinau P, Reshef D, Gil Cruz C, Ter Horst E, Kircher M, Reiter T, Heinze K, Ramos G. Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses. J Clin Invest 2019; 130
13.08.2019Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses
13.08.2019J Clin Invest 2019; 130
Rieckmann Max, van der Laan Anja M, Piek Jan J, Koch Charlotte, Wester Hans-Jürgen, Lapa Constantin, Bauer Wolfgang R, Ludewig Burkhard, Friedman Nir, Frantz Stefan, Hofmann Ulrich, Krijnen Paul Aj, Niessen Hans Wm, Delgobo Murilo, Gaal Chiara, Büchner Lotte, Steinau Philipp, Reshef Dan, Gil Cruz Cristina, Ter Horst Ellis N, Kircher Malte, Reiter Theresa, Heinze Katrin G, Ramos Gustavo Campos
Systems analysis reveals complex biological processes during virus infection fate decisions
Argilaguet J, Heath S, Ludewig B, Bocharov G, Kaisho T, Andreu D, Casella V, Gil Cruz C, Vidal E, Riera G, Esteve-Codina A, Pedragosa M, Meyerhans A. Systems analysis reveals complex biological processes during virus infection fate decisions. Genome Res 2019; 29:907-919.
28.05.2019Systems analysis reveals complex biological processes during virus infection fate decisions
28.05.2019Genome Res 2019; 29:907-919
Argilaguet Jordi, Heath Simon, Ludewig Burkhard, Bocharov Gennady, Kaisho Tsuneyasu, Andreu David, Casella Valentina, Gil Cruz Cristina, Vidal Enric, Riera Graciela, Esteve-Codina Anna, Pedragosa Mireia, Meyerhans Andreas
Fibroblastic reticular cells at the nexus of innate and adaptive immune responses
Pérez Shibayama C, Gil Cruz C, Ludewig B. Fibroblastic reticular cells at the nexus of innate and adaptive immune responses. Immunol Rev 2019; 289:31-41.
01.05.2019Fibroblastic reticular cells at the nexus of innate and adaptive immune responses
01.05.2019Immunol Rev 2019; 289:31-41
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Ludewig Burkhard
Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
Fässler M, Jörger M, Recher M, Risch L, Güsewell S, Risch M, Speiser D, Ludewig B, Levesque M, Dummer R, Siano M, Krolik M, Diem S, Mangana J, Hasan Ali O, Berner F, Bomze D, Ring S, Niederer R, Gil Cruz C, Pérez Shibayama C, Flatz L. Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients. J Immunother Cancer 2019; 7:50.
20.02.2019Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
20.02.2019J Immunother Cancer 2019; 7:50
Fässler Mirjam, Jörger Markus, Recher Mike, Risch Lorenz, Güsewell Sabine, Risch Martin, Speiser Daniel E, Ludewig Burkhard, Levesque Mitchell P, Dummer Reinhard, Siano Marco, Krolik Michal, Diem Stefan, Mangana Joanna, Hasan Ali Omar, Berner Fiamma, Bomze David, Ring Sandra, Niederer Rebekka, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Flatz Lukas
Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
Pérez Shibayama C, Gommerman J, Scandella E, Robinson M, Soneson C, Mack M, Turley S, Buechler M, López-Macías C, Li C, Novkovic M, Mörbe U, Printz A, Onder L, Cheng H, Gil Cruz C, Ludewig B. Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity. Sci Immunol 2018; 3
10.08.2018Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
10.08.2018Sci Immunol 2018; 3
Pérez Shibayama Christian Ivan, Gommerman Jennifer, Scandella Elke, Robinson Mark D, Soneson Charlotte, Mack Matthias, Turley Shannon J, Buechler Matthew B, López-Macías Constantino, Li Conglei, Novkovic Mario, Mörbe Urs, Printz Andrea, Onder Lucas, Cheng Hung-Wei, Gil Cruz Cristina, Ludewig Burkhard
Evolution of Salmonella Typhi outer membrane protein-specific T and B cell responses in humans following oral Ty21a vaccination: A randomized clinical trial
Carreño J, Pérez Shibayama C, Gil Cruz C, López-Macías C, Vernazza P, Ludewig B, Albrich W. Evolution of Salmonella Typhi outer membrane protein-specific T and B cell responses in humans following oral Ty21a vaccination: A randomized clinical trial. PloS one 2017; 12:e0178669.
01.06.2017Evolution of Salmonella Typhi outer membrane protein-specific T and B cell responses in humans following oral Ty21a vaccination: A randomized clinical trial
01.06.2017PloS one 2017; 12:e0178669
Carreño Juan Manuel, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, López-Macías Constantino, Vernazza Pietro, Ludewig Burkhard, Albrich Werner
Salmonella Typhi Porins OmpC and OmpF Are Potent Adjuvants for T-Dependent and T-Independent Antigens
Pérez-Toledo M, Bonifaz L, Isibasi A, Cunningham A, Arriaga-Pizano L, Pérez-Tapia S, Becker I, Moreno-Eutimio M, Pérez Shibayama C, Gil Cruz C, Pastelin-Palacios R, Valero-Pacheco N, López-Macías C. Salmonella Typhi Porins OmpC and OmpF Are Potent Adjuvants for T-Dependent and T-Independent Antigens. Front Immunol 2017; 8:230.
09.03.2017Salmonella Typhi Porins OmpC and OmpF Are Potent Adjuvants for T-Dependent and T-Independent Antigens
09.03.2017Front Immunol 2017; 8:230
Pérez-Toledo Marisol, Bonifaz Laura C, Isibasi Armando, Cunningham Adam F, Arriaga-Pizano Lourdes, Pérez-Tapia Sonia Mayra, Becker Ingeborg, Moreno-Eutimio Mario A, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Pastelin-Palacios Rodolfo, Valero-Pacheco Nuriban, López-Macías Constantino
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication
Kindler E, Karl N, Gaughan C, van Kuppeveld F, Silverman R, Keller M, Ludewig B, Bergmann C, Ziebuhr J, Weiss S, Kalinke U, Elliot R, Cervantes-Barragan L, Habjan M, Gil Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw H, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Thiel V. Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS Pathog 2017; 13:e1006195.
03.02.2017Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication
03.02.2017PLoS Pathog 2017; 13:e1006195
Kindler Eveline, Karl Nadja, Gaughan Christina, van Kuppeveld Frank J M, Silverman Robert H, Keller Markus, Ludewig Burkhard, Bergmann Cornelia C, Ziebuhr John, Weiss Susan R, Kalinke Ulrich, Elliot Ruth, Cervantes-Barragan Luisa, Habjan Matthias, Gil Cruz Cristina, Spanier Julia, Li Yize, Wilhelm Jochen, Rabouw Huib H, Züst Roland, Hwang Mihyun, V'kovski Philip, Stalder Hanspeter, Marti Sabrina, Thiel Volker