Martin Wetzke
Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status
Stallhofer J, Beigel F, Schnitzler F, Tillack-Schreiber C, Glas J, Lohse P, Wetzke M, Konrad-Zerna A, Friedrich M, Brand S. Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status. Inflamm Bowel Dis 2015; 21:2327-40.
01.10.2015Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status
01.10.2015Inflamm Bowel Dis 2015; 21:2327-40
Stallhofer Johannes, Beigel Florian, Schnitzler Fabian, Tillack-Schreiber Cornelia, Glas Jürgen, Lohse Peter, Wetzke Martin, Konrad-Zerna Astrid, Friedrich Matthias, Brand Stephan
Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
Tillack C, Koburger M, Wagner J, Glas J, Diegelmann J, Koglin S, Dombrowski Y, Schauber J, Wollenberg A, Maier H, Wetzke M, Ehmann L, Friedrich M, Laubender R, Papay P, Vogelsang H, Stallhofer J, Beigel F, Bedynek A, Brand S. Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. Gut 2013; 63:567-77.
06.03.2013Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
06.03.2013Gut 2013; 63:567-77
Tillack Cornelia, Koburger Maria, Wagner Johanna, Glas Jürgen, Diegelmann Julia, Koglin Sarah, Dombrowski Yvonne, Schauber Jürgen, Wollenberg Andreas, Maier Harald, Wetzke Martin, Ehmann Laura Maximiliane, Friedrich Matthias, Laubender Rüdiger P, Papay Pavol, Vogelsang Harald, Stallhofer Johannes, Beigel Florian, Bedynek Andrea, Brand Stephan
IRGM variants and susceptibility to inflammatory bowel disease in the German population
Glas J, Czamara D, Diegelmann J, Göke B, Friedrich M, Steib C, Beigel F, Wetzke M, Tsekeri E, Olszak T, Fries C, Stallhofer J, Bues S, Seiderer J, Brand S. IRGM variants and susceptibility to inflammatory bowel disease in the German population. PloS one 2013; 8:e54338.
24.01.2013IRGM variants and susceptibility to inflammatory bowel disease in the German population
24.01.2013PloS one 2013; 8:e54338
Glas Jürgen, Czamara Darina, Diegelmann Julia, Göke Burkhard, Friedrich Matthias, Steib Christian, Beigel Florian, Wetzke Martin, Tsekeri Eleni, Olszak Torsten, Fries Christoph, Stallhofer Johannes, Bues Stephanie, Seiderer Julia, Brand Stephan
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
Glas J, Duerr R, Franke A, Kamboh M, Achkar J, Balschun T, Müller-Myhsok B, Wolf C, Olszak T, Wetzke M, Diegelmann J, Pasciuto G, Czamara D, Seiderer J, Brand S. PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. PloS one 2012; 7:e52873.
27.12.2012PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
27.12.2012PloS one 2012; 7:e52873
Glas Jürgen, Duerr Richard H, Franke Andre, Kamboh M Ilyas, Achkar Jean-Paul, Balschun Tobias, Müller-Myhsok Bertram, Wolf Christiane, Olszak Torsten, Wetzke Martin, Diegelmann Julia, Pasciuto Giulia, Czamara Darina, Seiderer Julia, Brand Stephan
Analysis of IL12B gene variants in inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Ochsenkühn T, Göke B, Wetzke M, Steib C, Stallhofer J, Beigel F, Friedrich M, Tillack C, Fries C, Olszak T, Wagner J, Seiderer J, Brand S. Analysis of IL12B gene variants in inflammatory bowel disease. PloS one 2012; 7:e34349.
30.03.2012Analysis of IL12B gene variants in inflammatory bowel disease
30.03.2012PloS one 2012; 7:e34349
Glas Jürgen, Czamara Darina, Diegelmann Julia, Ochsenkühn Thomas, Göke Burkhard, Wetzke Martin, Steib Christian, Stallhofer Johannes, Beigel Florian, Friedrich Matthias, Tillack Cornelia, Fries Christoph, Olszak Torsten, Wagner Johanna, Seiderer Julia, Brand Stephan
PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background
Glas J, Czamara D, Diegelmann J, Karbalai N, Ochsenkühn T, Göke B, Steib C, Friedrich M, Stallhofer J, Tillack C, Beigel F, Wetzke M, Olszak T, Seiderer J, Wagner J, Brand S. PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. PloS one 2012; 7:e33682.
21.03.2012PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background
21.03.2012PloS one 2012; 7:e33682
Glas Jürgen, Czamara Darina, Diegelmann Julia, Karbalai Nazanin, Ochsenkühn Thomas, Göke Burkhard, Steib Christian, Friedrich Matthias, Stallhofer Johannes, Tillack Cornelia, Beigel Florian, Wetzke Martin, Olszak Torsten, Seiderer Julia, Wagner Johanna, Brand Stephan
The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease
Glas J, Czamara D, Diegelmann J, Friedrich M, Steib C, Beigel F, Olszak T, Tillack C, Fries C, Wetzke M, Bayrle C, Seiderer J, Brand S. The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease. PloS one 2011; 6:e29309.
29.12.2011The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease
29.12.2011PloS one 2011; 6:e29309
Glas Jürgen, Czamara Darina, Diegelmann Julia, Friedrich Matthias, Steib Christian, Beigel Florian, Olszak Torsten, Tillack Cornelia, Fries Christoph, Wetzke Martin, Bayrle Corinna, Seiderer Julia, Brand Stephan
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Folwaczny M, Ochsenkühn T, Göke B, Weidinger M, Olszak T, Beigel F, Wetzke M, Pfennig S, Tengler B, Fischer D, Seiderer J, Brand S. Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1917-24.
03.12.2010Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
03.12.2010Inflamm Bowel Dis 2010; 17:1917-24
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Folwaczny Matthias, Ochsenkühn Thomas, Göke Burkhard, Weidinger Maria, Olszak Torsten, Beigel Florian, Wetzke Martin, Pfennig Simone, Tengler Barbara, Fischer Daniel, Seiderer Julia, Brand Stephan
Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population
Glas J, Seiderer J, Tillack C, Paschos E, Wetzke M, Diegelmann J, Czamara D, Brand S. Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population. Inflamm Bowel Dis 2010; 17:1439-40.
03.12.2010Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population
03.12.2010Inflamm Bowel Dis 2010; 17:1439-40
Glas Jürgen, Seiderer Julia, Tillack Cornelia, Paschos Ekaterini, Wetzke Martin, Diegelmann Julia, Czamara Darina, Brand Stephan
Role of PPARG gene variants in inflammatory bowel disease
Glas J, Roeske D, Diegelmann J, Müller-Myhsok B, Ochsenkühn T, Göke B, Paschos E, Wetzke M, Pfennig S, Markus C, Seiderer J, Brand S. Role of PPARG gene variants in inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1057-8.
18.08.2010Role of PPARG gene variants in inflammatory bowel disease
18.08.2010Inflamm Bowel Dis 2010; 17:1057-8
Glas Jürgen, Roeske Darina, Diegelmann Julia, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Paschos Ekaterini, Wetzke Martin, Pfennig Simone, Markus Christian, Seiderer Julia, Brand Stephan
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
Jürgens M, Herrmann K, Lohse P, Göke B, Kreis M, Schnitzler F, Weidinger M, Beigel F, Tillack C, Pfennig S, Wagner J, Wetzke M, Glas J, Seiderer J, Laubender R, Brand S, Ochsenkühn T. The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype. J Gastroenterol 2010; 45:721-31.
29.04.2010The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
29.04.2010J Gastroenterol 2010; 45:721-31
Jürgens Matthias, Herrmann Karin, Lohse Peter, Göke Burkhard, Kreis Martin E, Schnitzler Fabian, Weidinger Maria, Beigel Florian, Tillack Cornelia, Pfennig Simone, Wagner Johanna, Wetzke Martin, Glas Jürgen, Seiderer Julia, Laubender Rüdiger P, Brand Stephan, Ochsenkühn Thomas
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
Jürgens M, Ochsenkühn T, Glas J, Göke B, Lohse P, Tillack C, Schnitzler F, Stallhofer J, Pfennig S, Beigel F, Wetzke M, Wagner J, Seiderer J, Weidinger M, Hartl F, Laubender R, Brand S. Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. Am J Gastroenterol 2010; 105:1811-9.
02.03.2010Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
02.03.2010Am J Gastroenterol 2010; 105:1811-9
Jürgens Matthias, Ochsenkühn Thomas, Glas Jürgen, Göke Burkhard, Lohse Peter, Tillack Cornelia, Schnitzler Fabian, Stallhofer Johannes, Pfennig Simone, Beigel Florian, Wetzke Martin, Wagner Johanna, Seiderer Julia, Weidinger Maria, Hartl Franziska, Laubender Rüdiger P, Brand Stephan
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
Török H, Müller-Myhsok B, Folwaczny C, Göke B, Folwaczny M, Ochsenkühn T, Lohse P, Klein W, Wetzke M, Teshome M, Tonenchi L, Endres I, Glas J, Brand S. Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol 2009; 104:1723-33.
19.05.2009Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
19.05.2009Am J Gastroenterol 2009; 104:1723-33
Török Helga P, Müller-Myhsok Bertram, Folwaczny Christian, Göke Burkhard, Folwaczny Matthias, Ochsenkühn Thomas, Lohse Peter, Klein Wolfram, Wetzke Martin, Teshome Molla Y, Tonenchi Laurian, Endres Ilona, Glas Jürgen, Brand Stephan
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
Glas J, Müller-Myhsok B, Ochsenkühn T, Göke B, Lohse P, Folwaczny M, Koletzko S, Lacher M, Schiemann U, Griga T, Epplen J, Klein W, Pfennig S, Wetzke M, Ripke S, Stallhofer J, Brand S. Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol 2009; 104:1737-44.
19.05.2009Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
19.05.2009Am J Gastroenterol 2009; 104:1737-44
Glas Jürgen, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Folwaczny Matthias, Koletzko Sibylle, Lacher Martin, Schiemann Uwe, Griga Thomas, Epplen Jörg T, Klein Wolfram, Pfennig Simone, Wetzke Martin, Ripke Stephan, Stallhofer Johannes, Brand Stephan
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
Glas J, Klein W, Epplen J, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Griga T, Jürgens M, Stallhofer J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török H, Brand S. rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2009; 104:665-72.
03.02.2009rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
03.02.2009Am J Gastroenterol 2009; 104:665-72
Glas Jürgen, Klein Wolfram, Epplen Jörg T, Schiemann Uwe, Mussack Thomas, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Griga Thomas, Jürgens Matthias, Stallhofer Johannes, Seiderer Julia, Pasciuto Giulia, Tillack Cornelia, Diegelmann Julia, Pfennig Simone, Konrad Astrid, Schmechel Silke, Wetzke Martin, Török Helga-Paula, Brand Stephan
Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status
Schmechel S, Konrad A, Diegelmann J, Glas J, Wetzke M, Paschos E, Lohse P, Göke B, Brand S. Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflamm Bowel Dis 2008; 14:204-12.
01.02.2008Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status
01.02.2008Inflamm Bowel Dis 2008; 14:204-12
Schmechel Silke, Konrad Astrid, Diegelmann Julia, Glas Jürgen, Wetzke Martin, Paschos Ekaterini, Lohse Peter, Göke Burkhard, Brand Stephan
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
Glas J, Klein W, Epplen J, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Griga T, Haller D, Pfennig S, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török H, Tonenchi L, Brand S. The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2007; 103:682-91.
20.12.2007The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
20.12.2007Am J Gastroenterol 2007; 103:682-91
Glas Jürgen, Klein Wolfram, Epplen Jörg T, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Mussack Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Griga Thomas, Haller Dirk, Pfennig Simone, Konrad Astrid, Schmechel Silke, Dambacher Julia, Seiderer Julia, Schroff Frieder, Wetzke Martin, Roeske Darina, Török Helga-Paula, Tonenchi Laurian, Brand Stephan
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants
Glas J, Epplen J, Schiemann U, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Folwaczny M, Mussack T, Klein W, Griga T, Maier K, Seiderer J, Wetzke M, Konrad A, Török H, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Brand S. rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PloS one 2007; 2:e819.
05.09.2007rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants
05.09.2007PloS one 2007; 2:e819
Glas Jürgen, Epplen Jörg T, Schiemann Uwe, Folwaczny Christian, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Müller-Myhsok Bertram, Folwaczny Matthias, Mussack Thomas, Klein Wolfram, Griga Thomas, Maier Kerstin, Seiderer Julia, Wetzke Martin, Konrad Astrid, Török Helga-Paula, Schmechel Silke, Tonenchi Laurian, Grassl Christine, Dambacher Julia, Pfennig Simone, Brand Stephan
Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes
Glas J, Folwaczny M, Ochsenkühn T, Brand S, Schnitzler F, Seiderer J, Lohse P, Schiemann U, Griga T, Epplen J, Klein W, Wetzke M, Mussack T, Müller-Myhsok B, Tonenchi L, Török H, Folwaczny C. Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes. Inflamm Bowel Dis 2006; 12:606-11.
01.07.2006Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes
01.07.2006Inflamm Bowel Dis 2006; 12:606-11
Glas Jürgen, Folwaczny Matthias, Ochsenkühn Thomas, Brand Stephan, Schnitzler Fabian, Seiderer Julia, Lohse Peter, Schiemann Uwe, Griga Thomas, Epplen Joerg T, Klein Wolfram, Wetzke Martin, Mussack Thomas, Müller-Myhsok Bertram, Tonenchi Laurian, Török Helga-Paula, Folwaczny Christian