Karin J Metzner
Frequency matters: comparison of drug resistance mutation detection by Sanger and next-generation sequencing in HIV-1.
Balakrishna S, Loosli T, Zaheri M, Frischknecht P, Huber M, Kusejko K, Yerly S, Leuzinger K, Perreau M, Ramette A, Wymant C, Fraser C, Kellam P, Gall A, Hirsch H, Stoeckle M, Rauch A, Cavassini M, Bernasconi E, Notter J, Calmy A, Günthard H, Metzner K, Kouyos R. Frequency matters: comparison of drug resistance mutation detection by Sanger and next-generation sequencing in HIV-1. J Antimicrob Chemother 2023; 78:656-664.
02.03.2023Frequency matters: comparison of drug resistance mutation detection by Sanger and next-generation sequencing in HIV-1.
02.03.2023J Antimicrob Chemother 2023; 78:656-664
Balakrishna Suraj, Loosli Tom, Zaheri Maryam, Frischknecht Paul, Huber Michael, Kusejko Katharina, Yerly Sabine, Leuzinger Karoline, Perreau Matthieu, Ramette Alban Nicolas, Wymant Chris, Fraser Christophe, Kellam Paul, Gall Astrid, Hirsch Hans H., Stoeckle Marcel, Rauch Andri, Cavassini Matthias, Bernasconi Enos, Notter Julia, Calmy Alexandra, Günthard Huldyrich F, Metzner Karin J, Kouyos Roger D
A Systematic Molecular Epidemiology Screen Reveals Numerous Human Immunodeficiency Virus (HIV) Type 1 Superinfections in the Swiss HIV Cohort Study.
Chaudron S, Leemann C, Kusejko K, Nguyen H, Tschumi N, Marzel A, Huber M, Böni J, Perreau M, Klimkait T, Yerly S, Ramette A, Hirsch H, Rauch A, Calmy A, Vernazza P, Bernasconi E, Cavassini M, Metzner K, Kouyos R, Günthard H, Swiss HIV Cohort Study. A Systematic Molecular Epidemiology Screen Reveals Numerous Human Immunodeficiency Virus (HIV) Type 1 Superinfections in the Swiss HIV Cohort Study. J Infect Dis 2022; 226:1256-1266.
28.09.2022A Systematic Molecular Epidemiology Screen Reveals Numerous Human Immunodeficiency Virus (HIV) Type 1 Superinfections in the Swiss HIV Cohort Study.
28.09.2022J Infect Dis 2022; 226:1256-1266
Chaudron Sandra E, Leemann Christine, Kusejko Katharina, Nguyen Huyen, Tschumi Nadine, Marzel Alex, Huber Michael, Böni Jürg, Perreau Matthieu, Klimkait Thomas, Yerly Sabine, Ramette Alban, Hirsch Hans H, Rauch Andri, Calmy Alexandra, Vernazza Pietro, Bernasconi Enos, Cavassini Matthias, Metzner Karin J, Kouyos Roger D, Günthard Huldrych F, Swiss HIV Cohort Study
Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment
Thorball C, Klimkait T, Yerly S, Battegay M, Rauch A, Schmid P, Bernasconi E, Cavassini M, Kouyos R, Günthard H, Metzner K, Fellay J, Perreau M, Böni J, Wieser M, Borghesi A, Bachmann N, Von Siebenthal C, Vongrad V, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Roth V, Kok Y, Parbhoo S, Swiss HIV Cohort Study. Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment. J Acquir Immune Defic Syndr 2020; 85:517-524.
01.12.2020Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment
01.12.2020J Acquir Immune Defic Syndr 2020; 85:517-524
Thorball Christian W, Klimkait Thomas, Yerly Sabine, Battegay Manuel, Rauch Andri, Schmid Patrick, Bernasconi Enos, Cavassini Matthias, Kouyos Roger D, Günthard Huldrych F, Metzner Karin J, Fellay Jacques, Perreau Matthieu, Böni Jürg, Wieser Mario, Borghesi Alessandro, Bachmann Nadine, Von Siebenthal Chantal, Vongrad Valentina, Turk Teja, Neumann Kathrin, Beerenwinkel Niko, Bogojeska Jasmina, Roth Volker, Kok Yik Lim, Parbhoo Sonali, Swiss HIV Cohort Study
Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial
Sculier D, Calmy A, Egger M, Limacher A, Schmid P, Günthard H, Decosterd L, Metzner K, Buzzi M, Cavassini M, Veraguth K, Braun D, Bernasconi E, Stoeckle M, Marinosci A, Yerly S, Wandeler G, and the Swiss HIV Cohort Study (SHCS). Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial. PLoS Med 2020; 17:e1003421.
10.11.2020Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial
10.11.2020PLoS Med 2020; 17:e1003421
Sculier Delphine, Calmy Alexandra, Egger Matthias, Limacher Andreas, Schmid Patrick, Günthard Huldrych F, Decosterd Laurent A, Metzner Karin J, Buzzi Marta, Cavassini Matthias, Veraguth Katja, Braun Dominique L, Bernasconi Enos, Stoeckle Marcel, Marinosci Annalisa, Yerly Sabine, Wandeler Gilles, and the Swiss HIV Cohort Study (SHCS)
Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART
Wan C, Yerly S, Battegay M, Walti L, Calmy A, Vernazza P, Bernasconi E, Cavassini M, Metzner K, Günthard H, Kouyos R, Klimkait T, Perreau M, Böni J, Bachmann N, Mitov V, Blanquart F, Céspedes S, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Fellay J, Roth V, Swiss HIV Cohort Study. Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART. Nat Commun 2020; 11:5542.
02.11.2020Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART
02.11.2020Nat Commun 2020; 11:5542
Wan Chenjie, Yerly Sabine, Battegay Manuel, Walti Laura, Calmy Alexandra, Vernazza Pietro, Bernasconi Enos, Cavassini Matthias, Metzner Karin J, Günthard Huldrych F, Kouyos Roger D, Klimkait Thomas, Perreau Matthieu, Böni Jürg, Bachmann Nadine, Mitov Venelin, Blanquart François, Céspedes Susana Posada, Turk Teja, Neumann Kathrin, Beerenwinkel Niko, Bogojeska Jasmina, Fellay Jacques, Roth Volker, Swiss HIV Cohort Study
HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection
Carlisle L, Günthard H, Bernasconi E, Vernazza P, Stoeckle M, Cavassini M, Nguyen A, Yerly S, Rauch A, Salazar-Vizcaya L, Fehr J, Braun D, Huber M, Böni J, Shah C, Mbunkah H, Metzner K, Turk T, Kouyos R. HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection. Viruses 2020; 12
31.10.2020HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection
31.10.2020Viruses 2020; 12
Carlisle Louisa A, Günthard Huldrych F, Bernasconi Enos, Vernazza Pietro, Stoeckle Marcel, Cavassini Matthias, Nguyen Aude, Yerly Sabine, Rauch Andri, Salazar-Vizcaya Luisa, Fehr Jan, Braun Dominique L, Huber Michael, Böni Jürg, Shah Cyril, Mbunkah Herbert A, Metzner Karin J, Turk Teja, Kouyos Roger D
Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment
Thorball C, Klimkait T, Yerly S, Battegay M, Rauch A, Schmid P, Bernasconi E, Cavassini M, Kouyos R, Günthard H, Metzner K, Fellay J, Perreau M, Böni J, Wieser M, Borghesi A, Bachmann N, Von Siebenthal C, Vongrad V, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Roth V, Kok Y, Parbhoo S, Swiss HIV Cohort Study. Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment. J Acquir Immune Defic Syndr 2020
18.08.2020Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment
18.08.2020J Acquir Immune Defic Syndr 2020
Thorball Christian W, Klimkait Thomas, Yerly Sabine, Battegay Manuel, Rauch Andri, Schmid Patrick, Bernasconi Enos, Cavassini Matthias, Kouyos Roger D, Günthard Huldrych F, Metzner Karin J, Fellay Jacques, Perreau Matthieu, Böni Jürg, Wieser Mario, Borghesi Alessandro, Bachmann Nadine, Von Siebenthal Chantal, Vongrad Valentina, Turk Teja, Neumann Kathrin, Beerenwinkel Niko, Bogojeska Jasmina, Roth Volker, Kok Yik Lim, Parbhoo Sonali, Swiss HIV Cohort Study
Viral diversity from next-generation sequencing of HIV-1 samples provides precise estimates of infection recency and time since infection
Carlisle L, Braun D, Rauch A, Calmy A, Cavassini M, Battegay M, Vernazza P, Bernasconi E, Günthard H, Kouyos R, Perreau M, Klimkait T, Yerly S, Turk T, Kusejko K, Metzner K, Leemann C, Schenkel C, Bachmann N, Posada S, Beerenwinkel N, Böni J, Swiss HIV Cohort Study. Viral diversity from next-generation sequencing of HIV-1 samples provides precise estimates of infection recency and time since infection. J Infect Dis 2019
04.03.2019Viral diversity from next-generation sequencing of HIV-1 samples provides precise estimates of infection recency and time since infection
04.03.2019J Infect Dis 2019
Carlisle Louisa A, Braun Dominique L, Rauch Andri, Calmy Alexandra, Cavassini Matthias, Battegay Manuel, Vernazza Pietro, Bernasconi Enos, Günthard Huldrych F, Kouyos Roger D, Perreau Matthieu, Klimkait Thomas, Yerly Sabine, Turk Teja, Kusejko Katharina, Metzner Karin J, Leemann Christine, Schenkel Corinne, Bachmann Nadine, Posada Susana, Beerenwinkel Niko, Böni Jürg, Swiss HIV Cohort Study
Tracing HIV-1 strains that imprint broadly neutralizing antibody responses
Kouyos R, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Metzner K, Günthard H, Trkola A, Chave J, Kuster H, Leemann C, Rusert P, Kadelka C, Huber M, Marzel A, Ebner H, Schanz M, Liechti T, Friedrich N, Braun D, Scherrer A, Weber J, Uhr T, Baumann N, Swiss HIV Cohort Study. Tracing HIV-1 strains that imprint broadly neutralizing antibody responses. Nature 2018; 561:406-410.
10.09.2018Tracing HIV-1 strains that imprint broadly neutralizing antibody responses
10.09.2018Nature 2018; 561:406-410
Kouyos Roger D, Cavassini Matthias, Bernasconi Enos, Hoffmann Matthias, Calmy Alexandra, Battegay Manuel, Rauch Andri, Yerly Sabine, Aubert Vincent, Klimkait Thomas, Böni Jürg, Metzner Karin J, Günthard Huldrych F, Trkola Alexandra, Chave Jean-Philippe, Kuster Herbert, Leemann Christine, Rusert Peter, Kadelka Claus, Huber Michael, Marzel Alex, Ebner Hanna, Schanz Merle, Liechti Thomas, Friedrich Nikolas, Braun Dominique L, Scherrer Alexandra U, Weber Jacqueline, Uhr Therese, Baumann Nicolas S, Swiss HIV Cohort Study
No Effect of Pegylated Interferon-α on Total HIV-1 DNA Load in HIV-1/HCV Coinfected Patients
Strouvelle V, Günthard H, Metzner K, Hoffmann M, Darling K, Rauch A, Stöckle M, Kouyos R, Kok Y, Scherrer A, Vongrad V, Braun D, Zurich Primary HIV Infection Study and the Swiss HIV Cohort Study. No Effect of Pegylated Interferon-α on Total HIV-1 DNA Load in HIV-1/HCV Coinfected Patients. J Infect Dis 2018; 217:1883-1888.
25.05.2018No Effect of Pegylated Interferon-α on Total HIV-1 DNA Load in HIV-1/HCV Coinfected Patients
25.05.2018J Infect Dis 2018; 217:1883-1888
Strouvelle Victoria P, Günthard Huldrych F, Metzner Karin J, Hoffmann Matthias, Darling Katharine, Rauch Andri, Stöckle Marcel, Kouyos Roger D, Kok Yik Lim, Scherrer Alexandra U, Vongrad Valentina, Braun Dominique L, Zurich Primary HIV Infection Study and the Swiss HIV Cohort Study
Incident Hepatitis C Virus Infections in the Swiss HIV Cohort Study: Changes in Treatment Uptake and Outcomes Between 1991 and 2013
Yerly S, Metzner K, Martinez de Tejada B, Martinetti G, Ledergerber B, Kovari H, Kouyos R, Klimkait T, Keiser O, Kaiser L, Kahlert C, Hösli I, Hoffmann M, Hirsch H, Hasse B, Müller N, Nadal D, Weber R, Vernazza P, Trkola A, Telenti A, Tarr P, Speck R, Schüpbach J, Schöni-Affolter F, Rudin C, Rickenbach M, Regenass S, Rauch A, Pantaleo G, Nicca D, Haerry D, Günthard H, Gorgievski M, Rauch A, Furrer H, Salazar-Vizcaya L, Keiser O, Bernasconi E, Schmid P, Stöckle M, Cavassini M, Ambrosioni J, Fehr J, Metzner K, Rohrbach J, Jaquier M, Schlauri M, Swiss HIV Cohort Study, Aubert V, Fux C, Furrer H, Fellay J, Fehr J, Elzi L, Egger M, Dollenmaier G, Cavassini M, Calmy A, Burton-Jeangros C, Bucher H, Böni J, Bernasconi E, Battegay M, Wandeler G. Incident Hepatitis C Virus Infections in the Swiss HIV Cohort Study: Changes in Treatment Uptake and Outcomes Between 1991 and 2013. Open Forum Infect Dis 2015; 2:ofv026.
25.03.2015Incident Hepatitis C Virus Infections in the Swiss HIV Cohort Study: Changes in Treatment Uptake and Outcomes Between 1991 and 2013
25.03.2015Open Forum Infect Dis 2015; 2:ofv026
Yerly S, Metzner K, Martinez de Tejada B, Martinetti G, Ledergerber B, Kovari H, Kouyos R, Klimkait T, Keiser O, Kaiser L, Kahlert Christian, Hösli I, Hoffmann M, Hirsch H H, Hasse B, Müller N, Nadal D, Weber R, Vernazza Pietro, Trkola A, Telenti A, Tarr P, Speck R, Schüpbach J, Schöni-Affolter F, Rudin C, Rickenbach M, Regenass S, Rauch A, Pantaleo G, Nicca D, Haerry D, Günthard H, Gorgievski M, Rauch Andri, Furrer Hansjakob, Salazar-Vizcaya Luisa, Keiser Olivia, Bernasconi Enos, Schmid Patrick, Stöckle Marcel, Cavassini Matthias, Ambrosioni Juan, Fehr Jan, Metzner Karin J, Rohrbach Janine, Jaquier Marie-Eve, Schlauri Marion, Swiss HIV Cohort Study, Aubert V, Fux C A, Furrer H, Fellay J, Fehr J, Elzi L, Egger M, Dollenmaier G, Cavassini M, Calmy A, Burton-Jeangros C, Bucher H C, Böni J, Bernasconi E, Battegay M, Wandeler Gilles
Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients
Metzner K, Günthard H, Weber R, Bernasconi E, Calmy A, Cavassini M, Vernazza P, Hirsch H, Furrer H, Aubert V, Klimkait T, Yerly S, Böni J, von Wyl V, Scherrer A, the Swiss HIV Cohort Study. Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients. AIDS 2014; 28:2231-2239.
24.09.2014Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients
24.09.2014AIDS 2014; 28:2231-2239
Metzner Karin J, Günthard Huldrych F, Weber Rainer, Bernasconi Enos, Calmy Alexandra, Cavassini Matthias, Vernazza Pietro, Hirsch Hans H, Furrer Hansjakob, Aubert Vincent, Klimkait Thomas, Yerly Sabine, Böni Jürg, von Wyl Viktor, Scherrer Alexandra U, the Swiss HIV Cohort Study
Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection
Metzner K, Aubert V, Furrer H, Battegay M, Vernazza P, Cavassini M, Calmy A, Bernasconi E, Weber R, Günthard H, Klimkait T, Yerly S, Böni J, Scherrer A, Preiswerk B, Joos B, von Wyl V, Leemann C, Rieder P, Braun D, Grube C, Kuster H, Swiss HIV Cohort Study. Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection. J Infect Dis 2013; 208:1102-12.
11.07.2013Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection
11.07.2013J Infect Dis 2013; 208:1102-12
Metzner Karin J, Aubert Vincent, Furrer Hansjakob, Battegay Manuel, Vernazza Pietro, Cavassini Matthias, Calmy Alexandra, Bernasconi Enos, Weber Rainer, Günthard Huldrych F, Klimkait Thomas, Yerly Sabine, Böni Jürg, Scherrer Alexandra U, Preiswerk Benjamin, Joos Beda, von Wyl Viktor, Leemann Christine, Rieder Philip, Braun Dominique, Grube Christina, Kuster Herbert, Swiss HIV Cohort Study