Bereich
Muskelzentrum | ALS Clinic
MUSKEL · Dept. Interdisziplinäre Medizinische Dienste
Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data.
Al Khleifat A, Iacoangeli A, Jones A, Van Vugt J, Moisse M, Shatunov A, Zwamborn R, van der Spek R, Cooper-Knock J, Topp S, van Rheenen W, Kenna B, van Eijk K, Kenna K, Byrne R, López V, Opie-Martin S, Vural A, Campos Y, Weber M, Smith B, Fogh I, Silani V, Morrison K, Dobson R, van Es M, McLaughlin R, Vourc'h P, Chio A, Corcia P, de Carvalho M, Gotkine M, Panades M, Mora J, Shaw P, Landers J, Glass J, Shaw C, Başak N, Hardiman O, Robberecht W, Van Damme P, van den Berg L, Veldink J, Al-Chalabi A. Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data. Front Cell Neurosci 2022; 16:1050596.
15.12.2022Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data.
15.12.2022Front Cell Neurosci 2022; 16:1050596
Al Khleifat Ahmad, Iacoangeli Alfredo, Jones Ashley R, Van Vugt Joke J F A, Moisse Matthieu, Shatunov Aleksey, Zwamborn Ramona A J, van der Spek Rick A A, Cooper-Knock Johnathan, Topp Simon, van Rheenen Wouter, Kenna Brendan, van Eijk Kristel R, Kenna Kevin, Byrne Ross P, López Victoria, Opie-Martin Sarah, Vural Atay, Campos Yolanda, Weber Markus, Smith Bradley, Fogh Isabella, Silani Vincenzo, Morrison Karen E, Dobson Richard, van Es Michael A, McLaughlin Russell L, Vourc'h Patrick, Chio Adriano, Corcia Philippe, de Carvalho Mamede, Gotkine Marc, Panades Monica Povedano, Mora Jesus S, Shaw Pamela J, Landers John E, Glass Jonathan D, Shaw Christopher E, Başak Nazli, Hardiman Orla, Robberecht Wim, Van Damme Philip, van den Berg Leonard H, Veldink Jan H, Al-Chalabi Ammar
Whole genome sequencing analysis reveals post-zygotic mutation variability in monozygotic twins discordant for amyotrophic lateral sclerosis.
Tazelaar G, Hop P, Seelen M, Van Vugt J, van Rheenen W, Kool L, van Eijk K, Gijzen M, Dooijes D, Moisse M, Calvo A, Moglia C, Brunetti M, Canosa A, Nordin A, Pardina J, Ravits J, Al-Chalabi A, Chio A, McLaughlin R, Hardiman O, Van Damme P, de Carvalho M, Neuwirth C, Weber M, Andersen P, van den Berg L, Veldink J, van Es M. Whole genome sequencing analysis reveals post-zygotic mutation variability in monozygotic twins discordant for amyotrophic lateral sclerosis. Neurobiol Aging 2022; 122:76-87.
17.11.2022Whole genome sequencing analysis reveals post-zygotic mutation variability in monozygotic twins discordant for amyotrophic lateral sclerosis.
17.11.2022Neurobiol Aging 2022; 122:76-87
Tazelaar Gijs H P, Hop Paul J, Seelen Meinie, Van Vugt Joke J F A, van Rheenen Wouter, Kool Lindy, van Eijk Kristel R, Gijzen Marleen, Dooijes Dennis, Moisse Matthieu, Calvo Andrea, Moglia Cristina, Brunetti Maura, Canosa Antonio, Nordin Angelica, Pardina Jesus S Mora, Ravits John, Al-Chalabi Ammar, Chio Adriano, McLaughlin Russell L, Hardiman Orla, Van Damme Philip, de Carvalho Mamede, Neuwirth Christoph, Weber Markus, Andersen Peter M, van den Berg Leonard H, Veldink Jan H, van Es Michael A
Cannabinoids to Improve Health-Related Quality of Life in Patients with Neurological or Oncological Disease: A Meta-Analysis.
Belgers V, Röttgering J, Douw L, Klein M, Ket J, van de Ven P, Würdinger T, van Linde M, Niers J, Weber M, Olde Rikkert M, Lopez-Sendon J, Arrieta O, Svendsen K, Chagas M, de Almeida C, Kouwenhoven M, de Witt Hamer P. Cannabinoids to Improve Health-Related Quality of Life in Patients with Neurological or Oncological Disease: A Meta-Analysis. Cannabis Cannabinoid Res 2022; 8:41-55.
21.07.2022Cannabinoids to Improve Health-Related Quality of Life in Patients with Neurological or Oncological Disease: A Meta-Analysis.
21.07.2022Cannabis Cannabinoid Res 2022; 8:41-55
Belgers Vera, Röttgering Jantine G, Douw Linda, Klein Martin, Ket Johannes C F, van de Ven Peter M, Würdinger Thomas, van Linde Myra E, Niers Johanna M, Weber Markus, Olde Rikkert Marcel G, Lopez-Sendon Jose, Arrieta Oscar, Svendsen Kristina B, Chagas Marcos H N, de Almeida Carlos M O, Kouwenhoven Mathilde C M, de Witt Hamer Philip C
Characterising ALS disease progression according to El Escorial and Gold Coast criteria.
de Jongh A, Braun N, Weber M, van Es M, Masrori P, Veldink J, Van Damme P, van den Berg L, van Eijk R. Characterising ALS disease progression according to El Escorial and Gold Coast criteria. J Neurol Neurosurg Psychiatry 2022; 93:865-870.
02.06.2022Characterising ALS disease progression according to El Escorial and Gold Coast criteria.
02.06.2022J Neurol Neurosurg Psychiatry 2022; 93:865-870
de Jongh Adriaan D, Braun Nathalie, Weber Markus, van Es Michael A, Masrori Pegah, Veldink Jan H, Van Damme Philip, van den Berg Leonard H, van Eijk Ruben P A
Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
van Rheenen W, van der Spek R, Bakker M, Van Vugt J, Hop P, Zwamborn R, de Klein N, Westra H, Bakker O, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker A, Gawor K, Westeneng H, Tazelaar G, van Eijk K, Kooyman M, Byrne R, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith B, Gromicho M, Chandran S, Pal S, Morrison K, Shaw P, Hardy J, Orrell R, Sendtner M, Meyer T, Başak N, van der Kooi A, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D'Alfonso S, Sorarù G, Siciliano G, Filosto M, Padovani A, Chio A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh R, Bell S, Vourc'h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina J, Assialioui A, Rojas-García R, Dion P, Ross J, Ludolph A, Weishaupt J, Brenner D, Freischmidt A, Bensimon G, Brice A, Dürr A, Payan C, Saker-Delye S, Wood N, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman D, Olsen C, Uitterlinden A, Hofman A, Rietschel M, Cichon S, Nöthen M, Amouyel P, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Traynor B, Singleton A, Mitne Neto M, Cauchi R, Ophoff R, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin V, Grosskreutz J, Roediger A, Gaur N, Jörk A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte O, Steinbach R, Hübner C, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glavač M, Glavač D, Stević Z, Drory V, Povedano M, Blair I, Kiernan M, Benyamin B, Henderson R, Furlong S, Mathers S, McCombe P, Needham M, Ngo S, Nicholson G, Pamphlett R, Rowe D, Steyn F, Williams K, Mather K, Sachdev P, Henders A, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau G, Silani V, Curtis C, Breen G, Glass J, Brown R, Landers J, Shaw C, Andersen P, Groen E, van Es M, Pasterkamp R, Fan D, Garton F, McRae A, Davey Smith G, Gaunt T, Eberle M, Mill J, McLaughlin R, Hardiman O, Kenna K, Wray N, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg L, Veldink J. Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet 2022; 54:361.
01.03.2022Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
01.03.2022Nat Genet 2022; 54:361
van Rheenen Wouter, van der Spek Rick A A, Bakker Mark K, Van Vugt Joke J F A, Hop Paul J, Zwamborn Ramona A J, de Klein Niek, Westra Harm-Jan, Bakker Olivier B, Deelen Patrick, Shireby Gemma, Hannon Eilis, Moisse Matthieu, Baird Denis, Restuadi Restuadi, Dolzhenko Egor, Dekker Annelot M, Gawor Klara, Westeneng Henk-Jan, Tazelaar Gijs H P, van Eijk Kristel R, Kooyman Maarten, Byrne Ross P, Doherty Mark, Heverin Mark, Al Khleifat Ahmad, Iacoangeli Alfredo, Shatunov Aleksey, Ticozzi Nicola, Cooper-Knock Johnathan, Smith Bradley N, Gromicho Marta, Chandran Siddharthan, Pal Suvankar, Morrison Karen E, Shaw Pamela J, Hardy John, Orrell Richard W, Sendtner Michael, Meyer Thomas, Başak Nazli, van der Kooi Anneke J, Ratti Antonia, Fogh Isabella, Gellera Cinzia, Lauria Giuseppe, Corti Stefania, Cereda Cristina, Sproviero Daisy, D'Alfonso Sandra, Sorarù Gianni, Siciliano Gabriele, Filosto Massimiliano, Padovani Alessandro, Chio Adriano, Calvo Andrea, Moglia Cristina, Brunetti Maura, Canosa Antonio, Grassano Maurizio, Beghi Ettore, Pupillo Elisabetta, Logroscino Giancarlo, Nefussy Beatrice, Osmanovic Alma, Nordin Angelica, Lerner Yossef, Zabari Michal, Gotkine Marc, Baloh Robert H, Bell Shaughn, Vourc'h Patrick, Corcia Philippe, Couratier Philippe, Millecamps Stéphanie, Meininger Vincent, Salachas François, Mora Pardina Jesus S, Assialioui Abdelilah, Rojas-García Ricardo, Dion Patrick A, Ross Jay P, Ludolph Albert C, Weishaupt Jochen H, Brenner David, Freischmidt Axel, Bensimon Gilbert, Brice Alexis, Dürr Alexandra, Payan Christine A M, Saker-Delye Safa, Wood Nicholas W, Topp Simon, Rademakers Rosa, Tittmann Lukas, Lieb Wolfgang, Franke Andre, Ripke Stephan, Braun Alice, Kraft Julia, Whiteman David C, Olsen Catherine M, Uitterlinden André G, Hofman Albert, Rietschel Marcella, Cichon Sven, Nöthen Markus M, Amouyel Philippe, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Traynor Bryan J, Singleton Andrew B, Mitne Neto Miguel, Cauchi Ruben J, Ophoff Roel A, Wiedau-Pazos Martina, Lomen-Hoerth Catherine, Van Deerlin Vivianna M, Grosskreutz Julian, Roediger Annekathrin, Gaur Nayana, Jörk Alexander, Barthel Tabea, Theele Erik, Ilse Benjamin, Stubendorff Beatrice, Witte Otto W, Steinbach Robert, Hübner Christian A, Graff Caroline, Brylev Lev, Fominykh Vera, Demeshonok Vera, Ataulina Anastasia, Rogelj Boris, Koritnik Blaž, Zidar Janez, Ravnik-Glavač Metka, Glavač Damjan, Stević Zorica, Drory Vivian, Povedano Monica, Blair Ian P, Kiernan Matthew C, Benyamin Beben, Henderson Robert D, Furlong Sarah, Mathers Susan, McCombe Pamela A, Needham Merrilee, Ngo Shyuan T, Nicholson Garth A, Pamphlett Roger, Rowe Dominic B, Steyn Frederik J, Williams Kelly L, Mather Karen A, Sachdev Perminder S, Henders Anjali K, Wallace Leanne, de Carvalho Mamede, Pinto Susana, Petri Susanne, Weber Markus, Rouleau Guy A, Silani Vincenzo, Curtis Charles J, Breen Gerome, Glass Jonathan D, Brown Robert H, Landers John E, Shaw Christopher E, Andersen Peter M, Groen Ewout J N, van Es Michael A, Pasterkamp R Jeroen, Fan Dongsheng, Garton Fleur C, McRae Allan F, Davey Smith George, Gaunt Tom R, Eberle Michael A, Mill Jonathan, McLaughlin Russell L, Hardiman Orla, Kenna Kevin P, Wray Naomi R, Tsai Ellen, Runz Heiko, Franke Lude, Al-Chalabi Ammar, Van Damme Philip, van den Berg Leonard H, Veldink Jan H
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS.
Hop P, Zwamborn R, Hannon E, Shireby G, Nabais M, Walker E, van Rheenen W, Van Vugt J, Dekker A, Westeneng H, Tazelaar G, van Eijk K, Moisse M, Baird D, Al Khleifat A, Iacoangeli A, Ticozzi N, Ratti A, Cooper-Knock J, Morrison K, Shaw P, Basak A, Chio A, Calvo A, Moglia C, Canosa A, Brunetti M, Grassano M, Gotkine M, Lerner Y, Zabari M, Vourc'h P, Corcia P, Couratier P, Mora Pardina J, Salas T, Dion P, Ross J, Henderson R, Mathers S, McCombe P, Needham M, Nicholson G, Rowe D, Pamphlett R, Mather K, Sachdev P, Furlong S, Garton F, Henders A, Lin T, Ngo S, Steyn F, Wallace L, Williams K, Neto M, Cauchi R, Blair I, Kiernan M, Drory V, Povedano M, de Carvalho M, Pinto S, Weber M, Rouleau G, Silani V, Landers J, Shaw C, Andersen P, McRae A, van Es M, Pasterkamp R, Wray N, McLaughlin R, Hardiman O, Kenna K, Tsai E, Runz H, Al-Chalabi A, van den Berg L, Van Damme P, Mill J, Veldink J. Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Sci Transl Med 2022; 14:eabj0264.
23.02.2022Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS.
23.02.2022Sci Transl Med 2022; 14:eabj0264
Hop Paul J, Zwamborn Ramona A J, Hannon Eilis, Shireby Gemma, Nabais Marta F, Walker Emma M, van Rheenen Wouter, Van Vugt Joke J F A, Dekker Annelot M, Westeneng Henk-Jan, Tazelaar Gijs H P, van Eijk Kristel R, Moisse Matthieu, Baird Denis, Al Khleifat Ahmad, Iacoangeli Alfredo, Ticozzi Nicola, Ratti Antonia, Cooper-Knock Jonathan, Morrison Karen E, Shaw Pamela J, Basak A Nazli, Chio Adriano, Calvo Andrea, Moglia Cristina, Canosa Antonio, Brunetti Maura, Grassano Maurizio, Gotkine Marc, Lerner Yossef, Zabari Michal, Vourc'h Patrick, Corcia Philippe, Couratier Philippe, Mora Pardina Jesus S, Salas Teresa, Dion Patrick A, Ross Jay P, Henderson Robert D, Mathers Susan, McCombe Pamela A, Needham Merrilee, Nicholson Garth A, Rowe Dominic B, Pamphlett Roger, Mather Karen A, Sachdev Perminder S, Furlong Sarah, Garton Fleur C, Henders Anjali K, Lin Tian, Ngo Shyuan T, Steyn Frederik J, Wallace Leanne, Williams Kelly L, Neto Miguel Mitne, Cauchi Ruben J, Blair Ian P, Kiernan Matthew C, Drory Vivian, Povedano Monica, de Carvalho Mamede, Pinto Susana, Weber Markus, Rouleau Guy A, Silani Vincenzo, Landers John E, Shaw Christopher E, Andersen Peter M, McRae Allan F, van Es Michael A, Pasterkamp R Jeroen, Wray Naomi R, McLaughlin Russell L, Hardiman Orla, Kenna Kevin P, Tsai Ellen, Runz Heiko, Al-Chalabi Ammar, van den Berg Leonard H, Van Damme Philip, Mill Jonathan, Veldink Jan H
Clinical trials in pediatric ALS: a TRICALS feasibility study.
Kliest T, van Eijk R, Al-Chalabi A, Albanese A, Andersen P, Amador M, BrÅthen G, Brunaud-Danel V, Brylev L, Camu W, de Carvalho M, Cereda C, Cetin H, Chaverri D, Chio A, Corcia P, Couratier P, De Marchi F, Desnuelle C, van Es M, Esteban J, Filosto M, GarcÍa Redondo A, Grosskreutz J, Hanemann C, Holmøy T, HØyer H, Ingre C, Koritnik B, Kuzma-Kozakiewicz M, Lambert T, Leigh P, Lunetta C, Mandrioli J, McDermott C, Meyer T, Mora J, Petri S, Povedano M, Reviers E, Riva N, Roes K, Rubio M, Salachas F, Sarafov S, Sorarù G, Stević Z, Svenstrup K, MØller A, Turner M, Van Damme P, Van Leeuwen L, Varona L, VÁzquez Costa J, Weber M, Hardiman O, van den Berg L. Clinical trials in pediatric ALS: a TRICALS feasibility study. Amyotroph Lateral Scler Frontotemporal Degener 2022; 23:481-488.
16.02.2022Clinical trials in pediatric ALS: a TRICALS feasibility study.
16.02.2022Amyotroph Lateral Scler Frontotemporal Degener 2022; 23:481-488
Kliest Tessa, van Eijk Ruben P A, Al-Chalabi Ammar, Albanese Alberto, Andersen Peter M, Amador Maria Del Mar, BrÅthen Geir, Brunaud-Danel Veronique, Brylev Lev, Camu William, de Carvalho Mamede, Cereda Cristina, Cetin Hakan, Chaverri Delia, Chio Adriano, Corcia Philippe, Couratier Philippe, De Marchi Fabiola, Desnuelle Claude, van Es Michael A, Esteban JesÚs, Filosto Massimiliano, GarcÍa Redondo Alberto, Grosskreutz Julian, Hanemann Clemens O, Holmøy Trygve, HØyer Helle, Ingre Caroline, Koritnik Blaž, Kuzma-Kozakiewicz Magdalena, Lambert Thomas, Leigh Peter N, Lunetta Christian, Mandrioli Jessica, McDermott Christopher J, Meyer Thomas, Mora Jesus S, Petri Susanne, Povedano Monica, Reviers Evy, Riva Nilo, Roes Kit C B, Rubio Miguel Á, Salachas François, Sarafov Stayko, Sorarù Gianni, Stević Zorica, Svenstrup Kirsten, MØller Anette Torvin, Turner Martin R, Van Damme Philip, Van Leeuwen Lucie A G, Varona Luis, VÁzquez Costa Juan F, Weber Markus, Hardiman Orla, van den Berg Leonard H
Evaluation of real-life outcome data of patients with spinal muscular atrophy treated with nusinersen in Switzerland.
Tscherter A, Rüsch C, Baumann D, Enzmann C, Hasselmann O, Jacquier D, Jung H, Kruijshaar M, Kuehni C, Neuwirth C, Stettner G, Klein-Franke A. Evaluation of real-life outcome data of patients with spinal muscular atrophy treated with nusinersen in Switzerland. Neuromuscul Disord 2022; 32:399-409.
09.02.2022Evaluation of real-life outcome data of patients with spinal muscular atrophy treated with nusinersen in Switzerland.
09.02.2022Neuromuscul Disord 2022; 32:399-409
Tscherter Anne, Rüsch Christina T, Baumann Dominique, Enzmann Cornelia, Hasselmann Oswald, Jacquier David, Jung Hans H, Kruijshaar Michelle E, Kuehni Claudia E, Neuwirth Christoph, Stettner Georg M, Klein-Franke Andreas
Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis.
Al Khleifat A, Iacoangeli A, Van Vugt J, Bowles H, Moisse M, Zwamborn R, van der Spek R, Shatunov A, Cooper-Knock J, Topp S, Byrne R, Gellera C, López V, Jones A, Opie-Martin S, Vural A, Campos Y, van Rheenen W, Kenna B, van Eijk K, Kenna K, Weber M, Smith B, Fogh I, Silani V, Morrison K, Dobson R, van Es M, McLaughlin R, Vourc'h P, Chio A, Corcia P, de Carvalho M, Gotkine M, Panadés M, Mora J, Shaw P, Landers J, Glass J, Shaw C, Başak N, Hardiman O, Robberecht W, Van Damme P, van den Berg L, Veldink J, Al-Chalabi A. Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis. NPJ Genom Med 2022; 7:8.
28.01.2022Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis.
28.01.2022NPJ Genom Med 2022; 7:8
Al Khleifat Ahmad, Iacoangeli Alfredo, Van Vugt Joke J F A, Bowles Harry, Moisse Matthieu, Zwamborn Ramona A J, van der Spek Rick A A, Shatunov Aleksey, Cooper-Knock Johnathan, Topp Simon, Byrne Ross P, Gellera Cinzia, López Victoria, Jones Ashley R, Opie-Martin Sarah, Vural Atay, Campos Yolanda, van Rheenen Wouter, Kenna Brendan, van Eijk Kristel R, Kenna Kevin, Weber Markus, Smith Bradley, Fogh Isabella, Silani Vincenzo, Morrison Karen E, Dobson Richard, van Es Michael A, McLaughlin Russell L, Vourc'h Patrick, Chio Adriano, Corcia Philippe, de Carvalho Mamede, Gotkine Marc, Panadés Monica P, Mora Jesus S, Shaw Pamela J, Landers John E, Glass Jonathan D, Shaw Christopher E, Başak Nazli, Hardiman Orla, Robberecht Wim, Van Damme Philip, van den Berg Leonard H, Veldink Jan H, Al-Chalabi Ammar
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
Benyamin B, Fominykh V, Brylev L, Graff C, Hübner C, Steinbach R, Witte O, Stubendorff B, Ilse B, Theele E, Barthel T, Demeshonok V, Ataulina A, Kiernan M, Blair I, Povedano M, Drory V, Stević Z, Glavač D, Ravnik-Glavač M, Zidar J, Koritnik B, Rogelj B, Jörk A, Gaur N, Roediger A, SLALOM Consortium, Amouyel P, Nöthen M, Cichon S, Rietschel M, Hofman A, Uitterlinden A, Olsen C, Whiteman D, Kraft J, PARALS Consortium, SLAGEN Consortium, Grosskreutz J, Van Deerlin V, Lomen-Hoerth C, Wiedau-Pazos M, Ophoff R, Cauchi R, Mitne Neto M, Singleton A, Traynor B, SLAP Consortium, Braun A, Veldink J, Gaunt T, Davey Smith G, McRae A, Garton F, Fan D, Pasterkamp R, van Es M, Groen E, Andersen P, Shaw C, Eberle M, Mill J, van den Berg L, Van Damme P, Al-Chalabi A, Franke L, Runz H, Tsai E, Wray N, Kenna K, Hardiman O, McLaughlin R, Landers J, Brown R, Glass J, Williams K, Steyn F, Rowe D, Pamphlett R, Nicholson G, Ngo S, Needham M, McCombe P, Mathers S, Furlong S, Mather K, Sachdev P, Breen G, Curtis C, Silani V, Rouleau G, Weber M, Petri S, Pinto S, de Carvalho M, Wallace L, Henders A, Henderson R, Sproviero D, Shaw P, Morrison K, Pal S, Chandran S, Gromicho M, Smith B, Cooper-Knock J, Ticozzi N, Shatunov A, Iacoangeli A, Hardy J, Orrell R, Cereda C, Corti S, Lauria G, Gellera C, Fogh I, Ratti A, van der Kooi A, Başak N, Meyer T, Sendtner M, Al Khleifat A, Heverin M, Doherty M, Shireby G, Deelen P, Bakker O, Westra H, de Klein N, Zwamborn R, Hop P, Van Vugt J, Bakker M, van der Spek R, Hannon E, Moisse M, Byrne R, Kooyman M, van Eijk K, Tazelaar G, Westeneng H, Gawor K, Dekker A, Dolzhenko E, Restuadi R, Baird D, van Rheenen W, Ripke S, Brenner D, Weishaupt J, Ludolph A, Ross J, Dion P, Rojas-García R, Assialioui A, Mora Pardina J, Salachas F, Meininger V, Freischmidt A, Bensimon G, Franke A, Lieb W, Tittmann L, Rademakers R, Topp S, Wood N, Saker-Delye S, Payan C, Dürr A, Brice A, Millecamps S, Couratier P, Corcia P, Grassano M, Canosa A, Brunetti M, Moglia C, Calvo A, Chio A, Padovani A, Filosto M, Siciliano G, Sorarù G, Beghi E, Pupillo E, Vourc'h P, Bell S, Baloh R, Gotkine M, Zabari M, Lerner Y, Nordin A, Osmanovic A, Nefussy B, Logroscino G, D'Alfonso S. Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet 2021; 53:1636-1648.
06.12.2021Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
06.12.2021Nat Genet 2021; 53:1636-1648
Benyamin Beben, Fominykh Vera, Brylev Lev, Graff Caroline, Hübner Christian A, Steinbach Robert, Witte Otto W, Stubendorff Beatrice, Ilse Benjamin, Theele Erik, Barthel Tabea, Demeshonok Vera, Ataulina Anastasia, Kiernan Matthew C, Blair Ian P, Povedano Monica, Drory Vivian, Stević Zorica, Glavač Damjan, Ravnik-Glavač Metka, Zidar Janez, Koritnik Blaž, Rogelj Boris, Jörk Alexander, Gaur Nayana, Roediger Annekathrin, SLALOM Consortium, Amouyel Philippe, Nöthen Markus M, Cichon Sven, Rietschel Marcella, Hofman Albert, Uitterlinden André G, Olsen Catherine M, Whiteman David C, Kraft Julia, PARALS Consortium, SLAGEN Consortium, Grosskreutz Julian, Van Deerlin Vivianna M, Lomen-Hoerth Catherine, Wiedau-Pazos Martina, Ophoff Roel A, Cauchi Ruben J, Mitne Neto Miguel, Singleton Andrew B, Traynor Bryan J, SLAP Consortium, Braun Alice, Veldink Jan H, Gaunt Tom R, Davey Smith George, McRae Allan F, Garton Fleur C, Fan Dongsheng, Pasterkamp R Jeroen, van Es Michael A, Groen Ewout J N, Andersen Peter M, Shaw Christopher E, Eberle Michael A, Mill Jonathan, van den Berg Leonard H, Van Damme Philip, Al-Chalabi Ammar, Franke Lude, Runz Heiko, Tsai Ellen, Wray Naomi R, Kenna Kevin P, Hardiman Orla, McLaughlin Russell L, Landers John E, Brown Robert H, Glass Jonathan D, Williams Kelly L, Steyn Frederik J, Rowe Dominic B, Pamphlett Roger, Nicholson Garth A, Ngo Shyuan T, Needham Merrilee, McCombe Pamela A, Mathers Susan, Furlong Sarah, Mather Karen A, Sachdev Perminder S, Breen Gerome, Curtis Charles J, Silani Vincenzo, Rouleau Guy A, Weber Markus, Petri Susanne, Pinto Susana, de Carvalho Mamede, Wallace Leanne, Henders Anjali K, Henderson Robert D, Sproviero Daisy, Shaw Pamela J, Morrison Karen E, Pal Suvankar, Chandran Siddharthan, Gromicho Marta, Smith Bradley N, Cooper-Knock Johnathan, Ticozzi Nicola, Shatunov Aleksey, Iacoangeli Alfredo, Hardy John, Orrell Richard W, Cereda Cristina, Corti Stefania, Lauria Giuseppe, Gellera Cinzia, Fogh Isabella, Ratti Antonia, van der Kooi Anneke J, Başak Nazli, Meyer Thomas, Sendtner Michael, Al Khleifat Ahmad, Heverin Mark, Doherty Mark, Shireby Gemma, Deelen Patrick, Bakker Olivier B, Westra Harm-Jan, de Klein Niek, Zwamborn Ramona A J, Hop Paul J, Van Vugt Joke J F A, Bakker Mark K, van der Spek Rick A A, Hannon Eilis, Moisse Matthieu, Byrne Ross P, Kooyman Maarten, van Eijk Kristel R, Tazelaar Gijs H P, Westeneng Henk-Jan, Gawor Klara, Dekker Annelot M, Dolzhenko Egor, Restuadi Restuadi, Baird Denis, van Rheenen Wouter, Ripke Stephan, Brenner David, Weishaupt Jochen H, Ludolph Albert C, Ross Jay P, Dion Patrick A, Rojas-García Ricardo, Assialioui Abdelilah, Mora Pardina Jesus S, Salachas François, Meininger Vincent, Freischmidt Axel, Bensimon Gilbert, Franke Andre, Lieb Wolfgang, Tittmann Lukas, Rademakers Rosa, Topp Simon, Wood Nicholas W, Saker-Delye Safa, Payan Christine A M, Dürr Alexandra, Brice Alexis, Millecamps Stéphanie, Couratier Philippe, Corcia Philippe, Grassano Maurizio, Canosa Antonio, Brunetti Maura, Moglia Cristina, Calvo Andrea, Chio Adriano, Padovani Alessandro, Filosto Massimiliano, Siciliano Gabriele, Sorarù Gianni, Beghi Ettore, Pupillo Elisabetta, Vourc'h Patrick, Bell Shaughn, Baloh Robert H, Gotkine Marc, Zabari Michal, Lerner Yossef, Nordin Angelica, Osmanovic Alma, Nefussy Beatrice, Logroscino Giancarlo, D'Alfonso Sandra
Reinnervation as measured by the motor unit size index is associated with preservation of muscle strength in amyotrophic lateral sclerosis, but not all muscles reinnervate
Chan Y, Stålberg E, Nandedkar S, de Carvalho M, Shaw P, McDermott C, Jenkins T, Castro J, Barkhaus P, Neuwirth C, Alix J, Weber M. Reinnervation as measured by the motor unit size index is associated with preservation of muscle strength in amyotrophic lateral sclerosis, but not all muscles reinnervate. Muscle Nerve 2021; 65:203-210.
09.11.2021Reinnervation as measured by the motor unit size index is associated with preservation of muscle strength in amyotrophic lateral sclerosis, but not all muscles reinnervate
09.11.2021Muscle Nerve 2021; 65:203-210
Chan Young, Stålberg Erik, Nandedkar Sanjeev, de Carvalho Mamede, Shaw Pamela J, McDermott Christopher J, Jenkins Thomas M, Castro José, Barkhaus Paul E, Neuwirth Christoph, Alix James J P, Weber Markus
Neue Therapieoptionen der spinalen Muskelatrophie
Neuwirth C. Neue Therapieoptionen der spinalen Muskelatrophie - Herausforderungen der neuen krankheitsmodifizierenden Therapiemöglichkeiten. MagBrain 2021; 5-21:43-47.
18.09.2021Neue Therapieoptionen der spinalen Muskelatrophie
18.09.2021MagBrain 2021; 5-21:43-47
Neuwirth Christoph
Challenges and opportunities for Multi-National Investigator-Initiated clinical trials for ALS: European and United States collaborations
Lingor P, Tostmann R, Neuwirth C, Meyer T, Lengenfeld T, Leha A, Kuttler J, Kollewe K, Kassubek J, Ilse B, Günther R, Ahmed R, Langbein T, Wuu J, Hennecke C, Hussain S, Statland J, Koch J, Benatar M. Challenges and opportunities for Multi-National Investigator-Initiated clinical trials for ALS: European and United States collaborations. Amyotroph Lateral Scler Frontotemporal Degener 2021; 22:419-425.
03.02.2021Challenges and opportunities for Multi-National Investigator-Initiated clinical trials for ALS: European and United States collaborations
03.02.2021Amyotroph Lateral Scler Frontotemporal Degener 2021; 22:419-425
Lingor Paul, Tostmann Ralf, Neuwirth Christoph, Meyer Thomas, Lengenfeld Teresa, Leha Andreas, Kuttler Josua, Kollewe Katja, Kassubek Jan, Ilse Benjamin, Günther René, Ahmed Raees, Langbein Thomas, Wuu Joanne, Hennecke Christiane, Hussain Sumaira, Statland Jeffrey M, Koch Jan C, Benatar Michael
The Effect of SMN Gene Dosage on ALS Risk and Disease Severity
Moisse M, Andersen P, Weber M, Başak N, Chen X, Eberle M, Al-Chalabi A, Shaw C, Shaw P, Morrison K, Landers J, Glass J, Robberecht W, van Es M, Van den Berg L, Veldink J, Van Damme P, Povedano M, Mora Pardina J, de Carvalho M, Zwamborn R, van Vugt J, van der Spek R, van Rheenen W, Kenna B, Van Eijk K, Kenna K, Corcia P, Couratier P, Vourc'h P, Hardiman O, McLaughin R, Gotkine M, Drory V, Ticozzi N, Silani V, Project MinE Sequencing Consortium. The Effect of SMN Gene Dosage on ALS Risk and Disease Severity. Ann Neurol 2021; 89:686-697.
15.01.2021The Effect of SMN Gene Dosage on ALS Risk and Disease Severity
15.01.2021Ann Neurol 2021; 89:686-697
Moisse Matthieu, Andersen Peter M, Weber Markus, Başak Nazli A, Chen Xiao, Eberle Michael A, Al-Chalabi Ammar, Shaw Chris, Shaw Pamela J, Morrison Karen E, Landers John E, Glass Jonathan D, Robberecht Wim, van Es Michael, Van den Berg Leonard, Veldink Jan, Van Damme Philip, Povedano Monica, Mora Pardina Jesus S, de Carvalho Mamede, Zwamborn Ramona A J, van Vugt Joke, van der Spek Rick, van Rheenen Wouter, Kenna Brendan, Van Eijk Kristel, Kenna Kevin, Corcia Philippe, Couratier Philippe, Vourc'h Patrick, Hardiman Orla, McLaughin Russell, Gotkine Marc, Drory Vivian, Ticozzi Nicola, Silani Vincenzo, Project MinE Sequencing Consortium
MUNIX in children with spinal muscular atrophy: An unexpected journey
Neuwirth C, Weber M. MUNIX in children with spinal muscular atrophy: An unexpected journey. Muscle Nerve 2020; 62:565-566.
11.09.2020MUNIX in children with spinal muscular atrophy: An unexpected journey
11.09.2020Muscle Nerve 2020; 62:565-566
Neuwirth Christoph, Weber Markus
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors
Haider A, Pacher P, Herde A, Spinelli F, Ahmed H, Atz K, Keller C, Weber M, Schibli R, Mu L, Grether U, Knuesel I, Bartelmus C, Gobbi L, Kretz J, Ullmer C, Brink A, Honer M, Woltering T, Muri D, Iding H, Bürkler M, Binder M, Ametamey S. Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors. J Med Chem 2020; 63:10287-10306.
01.09.2020Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors
01.09.2020J Med Chem 2020; 63:10287-10306
Haider Ahmed, Pacher Pal, Herde Adrienne Müller, Spinelli Francesco, Ahmed Hazem, Atz Kenneth, Keller Claudia, Weber Markus, Schibli Roger, Mu Linjing, Grether Uwe, Knuesel Irene, Bartelmus Christian, Gobbi Luca, Kretz Julian, Ullmer Christoph, Brink Andreas, Honer Michael, Woltering Thomas J, Muri Dieter, Iding Hans, Bürkler Markus, Binder Martin, Ametamey Simon M
TRICALS: creating a highway toward a cure
van Eijk R, Hardiman O, Al-Chalabi A, van Es M, Reviers E, Povedano M, Corcia P, Ingre C, Weber M, Chio A, Van Damme P, Roes K, McDermott C, Kliest T, van den Berg L. TRICALS: creating a highway toward a cure. Amyotroph Lateral Scler Frontotemporal Degener 2020; 21:496-501.
09.07.2020TRICALS: creating a highway toward a cure
09.07.2020Amyotroph Lateral Scler Frontotemporal Degener 2020; 21:496-501
van Eijk Ruben P A, Hardiman Orla, Al-Chalabi Ammar, van Es Michael A, Reviers Evy, Povedano Monica, Corcia Philippe, Ingre Caroline, Weber Markus, Chio Adriano, Van Damme Philip, Roes Kit C B, McDermott Christopher J, Kliest Tessa, van den Berg Leonard H
Measuring Outcomes in Adults with Spinal Muscular Atrophy - Challenges and Future Directions - Meeting Report
Sansone V, Kleinschnitz C, Vazquez-Costa J, Neuwirth C, Lochmüller H, Mercuri E, Delstanche S, Attarian S, Walter M, Hagenacker T. Measuring Outcomes in Adults with Spinal Muscular Atrophy - Challenges and Future Directions - Meeting Report. J Neuromuscul Dis 2020
12.06.2020Measuring Outcomes in Adults with Spinal Muscular Atrophy - Challenges and Future Directions - Meeting Report
12.06.2020J Neuromuscul Dis 2020
Sansone V A, Kleinschnitz C, Vazquez-Costa J F, Neuwirth Christoph, Lochmüller H, Mercuri E, Delstanche S, Attarian S, Walter M C, Hagenacker T
Estimating the Number of Motor Neurons: First Go to the Roots Before Cropping the Fruits
Neuwirth C, Weber M. Estimating the Number of Motor Neurons: First Go to the Roots Before Cropping the Fruits. Muscle Nerve 2020; 62:154-155.
29.05.2020Estimating the Number of Motor Neurons: First Go to the Roots Before Cropping the Fruits
29.05.2020Muscle Nerve 2020; 62:154-155
Neuwirth Christoph, Weber Markus
Nine Hole Peg Test and Transcranial Magnetic Stimulation: Useful to Evaluate Dexterity of the Hand and Disease Progression in Amyotrophic Lateral Sclerosis
Czell D, Neuwirth C, Weber M, Sartoretti-Schefer S, Gutzeit A, Reischauer C. Nine Hole Peg Test and Transcranial Magnetic Stimulation: Useful to Evaluate Dexterity of the Hand and Disease Progression in Amyotrophic Lateral Sclerosis. Neurol Res Int 2019; 2019:7397491.
07.11.2019Nine Hole Peg Test and Transcranial Magnetic Stimulation: Useful to Evaluate Dexterity of the Hand and Disease Progression in Amyotrophic Lateral Sclerosis
07.11.2019Neurol Res Int 2019; 2019:7397491
Czell David, Neuwirth Christoph, Weber Markus, Sartoretti-Schefer Sabine, Gutzeit Andreas, Reischauer Carolin