Unit
Division of Infectious Diseases, Infection Prevention and Travel Medicine
INFEKT · Dept. I
Assessment of Torque Teno Virus (TTV) viral load as marker for baseline immunity in healthcare workers
Dec 2, 2024This project will retrospectively assess the association of SARS-CoV-2 vaccination status with TTV viral loads in a cohort of healthcare workers and correlation with susceptibility to respiratory infections, determined by total number of influenza-li...
Clinical Studies - Dec 2, 2024 - Oct 31, 2025
Scheduled
Project leader: Kohler Philipp
Members: Kuster Stefan, Kahlert Christian, Grässli Fabian
Humoral immunity and risk factors for Alongshan-virus in healthcare workers from Eastern Switzerland –proposal for a seroepidemiologic analysis
Aug 1, 2024In dieser prospektiven Studie innerhalb der SURPRISE+ Kohorte möchten wir die Seroprävalenz und Serokonversion gegen das Alongshan-Virus (ALSV). ALSV ist ein Flavivirus, welches ein FSME-ähnliches Krankheitsbild auslösen kann. Das Virus wird häufig i...
Clinical Studies - Aug 1, 2024 - Feb 28, 2026
Ongoing
Project leader: Kohler Philipp
Members: Frischknecht Manuel, Kuster Stefan, Kahlert Christian
Influence of COVID-19 Pandemic on the Incidence of Acute Otitis Media with Complications: A Retrospective Cohort Study at a Tertiary Care Hospital
Jul 1, 2024Acute otitis media (AOM) is typically a condition that resolves without long-term sequelae. However, it may be associated with complications. These can range from local complications such as involvement of the inner ear, potentially leading to persis...
Clinical Studies - Jul 1, 2024 - Jul 1, 2025
Ongoing
Project leader: Stöckli Sandro
Members: Albrich Werner, Menegotto Richard
Point Prevalence of Antibiotic Resistance in Helicobacter pylori in St. Gallen: An Observational Pilot Trial
May 1, 2024Evaluation der Antibiotika-Resistenz von Helicobacter pylori Magen und Überprüfung der Konsistenz von Resistenzdaten aus dem Stuhl und aus Magenbiopsien
Clinical Studies - May 1, 2024 - Jun 30, 2025
Scheduled
Project leader: Kueres-Wiese Alexander
Members: Kuster Stefan, Frei Nicola Fabian, Borovicka Jan
Large language models for the identification of etiotypes in Chronic Obstructive Lung Diseases
Mar 1, 2024Recent guidelines proposed new taxonomic classifications for COPD, so-called etiotypes, which have clinical relevance for management and treatment of patients. This project hypothesizes that information extracted from patients' electronic health reco...
Fundamental Research - Mar 1, 2024 - Feb 28, 2025
Ongoing
Project leader: Baty Florent
Members: Brutsche Martin, Albrich Werner, Hastings Janna, Kozu Kei, Toromanovic Tim
OASIS – Optimierung der Antibiotikanutzung im stationären Setting durch Interprofessionelles Stewardship
Dec 1, 2023Zur Optimierung des Antibiotikaverbrauchs wurde am Kantonsspital St.Gallen ein Antimicrobial Stewardship Programm (ASP) eingeführt. Für die erfolgreiche Umsetzung braucht es die aktive Einbindung aller beteiligten Fachpersonen über den gesamten Verso...
Healthcare Research - Dec 1, 2023 - Aug 31, 2024
Automatically Closed
Project leader: Künzler-Heule Patrizia
Members: Kohler Philipp, Kuster Stefan, Ledergerber Katrin, Flury Domenica, Schoop Barbara, Nicca D
Meaningful Patient and Public Involvement in the SHCS: A methods review and mixed-method study
Jul 1, 2023
Clinical Studies - Jul 1, 2023 - Dec 31, 2025
Automatically Closed
Project leader: Notter Julia
Members: Jackson-Perry David
Impact of Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC) on the gut microbiome and microbiome-mediated toxicity of TDF/FTC in men using event-based HIV Pre- Exposure prophylaxis
Jun 1, 2023
Clinical Studies - Jun 1, 2023 - Mar 31, 2025
Ongoing
Project leader: Notter Julia
Members: Kahlert Christian
mBiomR; Unravelling the Mechanisms and Dynamics Underlying the Response of Intestinal Bacteria from the ESKAPE group to Antimicrobial Treatment
Mar 1, 2023With this longitudinal, large-scale metagenomics, multi-assay study (mBiomR) on adult hospitalised Population ,which we will start in the beginning of 2023, we aim to explore the distribution dynamics of Gram-negative pathogens and Enterococcus faec...
Fundamental Research - Mar 1, 2023 - Mar 1, 2027
Ongoing
Project leader: Babouee Flury Baharak
Exploring the impact of hexagonal boron nitride (nanomedicines) on bacterial quorum sensing communication and its consequences on bacterial lung invasionand pathogenesis
Jan 3, 2023In this interdisciplinary collaboration between Empa's Laboratory for Particles-Biology Interactions (Particles@Barriers subgroup) and the KSSG (Infektiologie/Spitalhygiene), we aim to study whether hexagonal boron nitride (hBN) could modulate host-i...
Fundamental Research - Jan 3, 2023 - Jan 2, 2024
Automatically Closed
Project leader: Albrich Werner, Bürki-Turnherr Tina, Kahlert Christian
Members: Nigg Susanne
Retinale endotheliale Dysfunktion bei Raynaud-Phänomen
Jun 1, 2022Untersuchung der Endothelfunktion retinaler Gefässe bei Patienten mit einem Raynaud Phänomen mit dem Ziel, Veränderungen im Vergleich zu gesunden Menschen darzustellen und Beziehungen zwischen Parametern der retinalen Endothelfunktion, der Kapillarmi...
Clinical Studies - Jun 1, 2022 - Jun 30, 2025
Ongoing
Project leader: Neumann Thomas
Members: Todorova Margarita, Güsewell Sabine
Fluorescence-based rapid diagnostic tool for sensitive and selective Detection Of uReaSeproducing bacTEria causing ventilator-associated Pneumonia - DOORSTEP
May 2, 2022
Fundamental Research - May 2, 2022 - May 1, 2023
Automatically Closed
Project leader: Giovannini G
Members: Kahlert Christian, Nigg Susanne
Treatment and outcomes of surgical site infections after spinal instrumentation – a retrospective cohort study
May 2, 2022
Clinical Studies - May 2, 2022 - Dec 31, 2024
Ongoing
Project leader: Strahm Carol
Members: Cosma Tudor, Zdravkovic Vilijam
Symptoms compatible with long-COVID in SARS-CoV-2 positive and negative healthcare workers – analysis of prospective cohort data
Mar 1, 2022In this analysis, we are aiming to determine the impact of viral variant and of vaccination on the occurence and the temporal dynamics of long COVID symptoms in healthcare workers.
Healthcare Research - Mar 1, 2022 - Dec 31, 2022
Automatically Closed
Project leader: Kohler Philipp
Analysis of the effect of biological therapy on SARS-CoV-2-specific antibody levels following booster vaccination in patients with inflammatory bowel disease
Jan 20, 2022This is a national multi-center cohort confirmatory study which is designed as a prospective observational trial combined with retrospective data collection. Prospective data are collected through a patient questionnaire and assessment of blood sam...
Clinical Studies - Jan 20, 2022 - Mar 30, 2023
Automatically Closed
Project leader: Brand Stephan
Members: König Marius, Dütschler Joel, Krieger-Grübel Claudia, Eckhold Annika, Truniger Samuel, Frei Nicola Fabian, Albrich Werner
Regional spread of an untypical ESBL-E.coli ST131H89 clone among different human and environmental reservoirs in Western Switzerland
Jan 1, 2022We are investigating the clonal dissemination of a novel ESBL-producing Escherichia coli (ST131 H89) in Western Switzerland.
Healthcare Research - Jan 1, 2022 - Jun 30, 2023
Automatically Closed
Project leader: Kohler Philipp
Deciphering the resistance mechanisms of E. coli and P. aeruginosa from UTI and SSI in Tanzania
Nov 1, 2021This study investigates antimicrobial resistance mechanisms of E.coli and P. aeruginosa isolated from patients with urinary tract infections or surgical site infections. The samples are collected from patients at St. Francis Referral Hospital in Ifak...
Fundamental Research - Nov 1, 2021 - Nov 1, 2024
Automatically Closed
Project leader: Babouee Flury Baharak
Members: Macha Magreth
Cognitive Outcome 1 year after COVID-19 – A Pilot Study (CogCOVID)
Oct 19, 2021This prospective observational pilot study examines cognitive function 1 year after SARS-Cov-2 disease. Study population consists of formerly hospitalized non-ventilated COVID-19 patients (nvCOVID) and ventilated patients with COVID-19-ARDS (cARDS) t...
Clinical Studies - Oct 19, 2021 - Dec 31, 2022
Automatically Closed
Project leader: Göhl-Freyn Kristina, Felbecker Ansgar
Members: Albrich Werner, Schmid Dagmar, Kleger Gian-Reto, Schrag Claudia, Pietsch Urs
Covid 19 Impfantwort, Bedarf und Reaktion auf mögliche Booster- Impfung bei Patienten mit soliden Neoplasien
Oct 1, 2021Patienten mit malignen Erkrankungen stellen eine durch die SARS-CoV-2-Pandemie hoch gefährdete Gruppe dar mit einem hohen Hospitalisations- und Mortalitätsrisiko. Eine Impfung gegen SARS-COV2 stellt neben allgemeinen Schutzmassnahmen das wichtigste E...
Clinical Studies - Oct 1, 2021 - Feb 28, 2021
Automatically Closed
Project leader: Fischer Stefanie
Members: Silzle Tobias, Demmer-Steingruber Ruth, Albrich Werner, Kahlert Christian
Response to COVID-19 vaccination and COVID-19 infections after vaccination in patients with haematological malignancies
May 1, 2021The prevalence and mortality of COVID-19 are higher in patients with haematological malignancies (HM) compared to the general population (Vijenthira et al. 2020). Two SARS-CoV-2 messenger RNA (mRNA) vaccines have been approved by Swissmedic, both are...
Clinical Studies - May 1, 2021 - Oct 1, 2022
Completed
Project leader: Silzle Tobias
Members: Fischer Stefanie, Kahlert Christian, Albrich Werner