Unit
Gastroenterology/Hepatology
GASTRO · Dept. I
I6T-MC-AMAN
Jan 1, 2018A Phase 3, Multicenter, Randomized, Double-Blind, Parallel, Placebo-Controlled Induction Study of Mirikizumab in Conventional-Failed and Biologic-Failed Patients with Moderately to Severely Active Ulcerative Colitis LUCENT 1
Clinical Studies - Jan 1, 2018 - Feb 1, 2021
Completed
Project leader: Brand Stephan
Members: Krieger-Grübel Claudia, Sulz Michael, Smolders Jolijn
I6T-MC-AMBG
Jan 1, 2018A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, Placebo-Controlled Maintenance Study of Mirikizumab in Patients with Moderately to Severely Active Ulcerative Colitis LUCENT 2
Clinical Studies - Jan 1, 2018 - Jun 1, 2021
Automatically Closed
Project leader: Brand Stephan
Members: Sulz Michael, Krieger-Grübel Claudia, Smolders Jolijn
ACRE
Jan 1, 2018A MULTICENTER, MULTI-NATIONAL, RANDOMISED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL GROUP, PHASE IIA STUDY TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF AN ANTHOCYANIN RICH EXTRACT (ACRE) IN PATIENTS WITH ULCERATIVE COLITIS.
Clinical Studies - Jan 1, 2018 - Jul 1, 2021
Completed
Project leader: Brand Stephan
Members: Stillhard Roman, Sulz Michael, Krieger-Grübel Claudia, Smolders Jolijn
Anal Mapping Biopsies for Human Papilloma Virus (HPV) Associated Lesions
Oct 4, 2017Es gibt keinen eindeutigen Goldstandard für die Diagnose von HPV-assoziierten Analläsionen. Die übliche Diagnostik erfolgt mittels hochauflösender Anoskopie (HRA). Die diagnostische Genauigkeit dieser Methode ist jedoch unklar und stark vom Prüfer ab...
Clinical Studies - Oct 4, 2017 - Feb 4, 2018
Completed
Project leader: Baumeler Stephan, Borovicka Jan, Marti Lukas
Members: Maurus Christine
First Experiences with Screening of Anal Intraepithelial Neoplasia (AIN): a Single Center Retrospective Data-Analysis
Sep 1, 2017Hintergrund Zwischen Human Papilloma Virus (HPV) und Analkrebs besteht eine starke Korrelation. Wie beim Cervixkarzinom der Frau sind mehr als 80% der Analkarzinome durch HPV bedingt. Analkrebs geht meist aus Vorläuferläsionen, den analen intraepithe...
Clinical Studies - Sep 1, 2017 - Sep 2, 2018
Automatically Closed
Project leader: Baumeler Stephan
Members: Maurus Christine, Marti Lukas, Borovicka Jan, Bock Susanne, Bischofberger Stephan, Schmid Patrick
GA29145
Aug 28, 2017AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE PREVIOUSLY ENROLLED IN THE ETROLIZUMAB PHASE III PROTOCOL GA29144
Clinical Studies - Aug 28, 2017 - Aug 28, 2021
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
GA29144/Bergamot
Aug 1, 2017A PHASE III, RANDOMIZED, DOUBLEBLIND, PLACEBOCONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ETROLIZUMAB AS AN INDUCTION AND MAINTENANCE TREATMENT FOR PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE
Clinical Studies - Aug 1, 2017 - Aug 1, 2021
Automatically Closed
Project leader: Borovicka Jan, Brand Stephan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
ICL670, Deferasirox
Aug 1, 2017A phase II, multicenter, open-label, randomized two-year study to evaluate the efficacy and safety of deferasirox film-coated tablet versus phlebotomy in patients with Hereditary Hemochromatosis
Clinical Studies - Aug 1, 2017 - Jan 1, 2020
Completed
Project leader: Semela David
Members: Stillhard Roman
Amiselimod
Jun 1, 2017A Phase 3, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study of Amiselimod (MT-1303) in the Induction and Maintenance of Clinical Response and Remission in Subjects With Moderate to Severe Ulcerative Colitis
Clinical Studies - Jun 1, 2017 - Sep 27, 2022
Automatically Closed
Members: Knellwolf Christina, Dora Barbara, Krieger-Grübel Claudia, Sulz Michael
Evaluation of High Resolution Endoscopy Compared to the High Resolution Anoscopy for Detection of Early Dysplastic or Neoplastic Lesions of the Anal Canal in High−Risk Patients
Apr 17, 2017There is a strong correlation between HPV infection and anal squamous cell cancer (SCC). Just like in nearly 100% of cervical cancer, infection with human papillomavirus (HPV) high-risk types causes more than 80% of anal cancer. Nevertheless the natu...
Clinical Studies - Apr 17, 2017 - Apr 17, 2019
Automatically Closed
Project leader: Baumeler Stephan
Members: Borovicka Jan, Maurus Christine
Allergan AURORA
Apr 1, 2017A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis
Clinical Studies - Apr 1, 2017 - Jan 1, 2025
Aborted
Project leader: Semela David
GFT505-315
Mar 1, 2017A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Elafibranor in Patients with Nonalcoholic Steatohepatitis (NASH) and fibrosis
Clinical Studies - Mar 1, 2017 - Nov 1, 2020
Aborted
Members: Stillhard Roman, Semela David
M14-533
Jan 1, 2017A Phase 3 Multicenter, Long-Term Extension Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) in Subjects with Ulcerative Colitis
Clinical Studies - Jan 1, 2017 - Dec 1, 2022
Automatically Closed
Project leader: Sulz Michael
Members: Smolders Jolijn, Brand Stephan
HEMATITE
Dec 16, 2016Quality of Life measurement using wrist actigraph in HCV genotype 1 infected, Treatment naive patients suffering from fatique and receiving Viekirax/Exviera.
Clinical Studies - Dec 16, 2016 - Dec 16, 2018
Completed
Project leader: Semela David
Members: Stillhard Roman
Mongersen GED-0301
Dec 1, 2016A Phase 3, randomized, double-blind, placebo-controlled, multicenter study to investigate the efficacy and safety of mongersen (GED-0301) for the treatment of subjects with active Crohn’s disease.
Clinical Studies - Dec 1, 2016 - Dec 1, 2018
Completed
Members: Dora Barbara, Knellwolf Christina, Krieger-Grübel Claudia, Sulz Michael
PCG-4/UCR
Dec 1, 2016Randomized, double-blind, double-dummy, placebo-controlled, Phase III clinical trial on the efficacy and safety of a 48-weeks treatment with gastroresistant phosphatidylcholine (LT-02) versus placebo versus mesalamine for maintenance of remission in...
Clinical Studies - Dec 1, 2016 - Dec 1, 2018
Completed
Members: Dora Barbara, Knellwolf Christina, Krieger-Grübel Claudia, Sulz Michael
Abbvie M14-234
Dec 1, 2016A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
Clinical Studies - Dec 1, 2016 - Dec 1, 2018
Automatically Closed
Members: Dora Barbara, Knellwolf Christina, Krieger-Grübel Claudia, Sulz Michael
SASL 38 Swiss Cohort Study on Autoimmun Hepatitis
Sep 14, 2016Research project in which biological material is sampled from humans and health-related personal data is collected for research.
Clinical Studies - Sep 14, 2016 - Sep 14, 2022
Automatically Closed
Project leader: Semela David
Members: Stillhard Roman
SASL 39 Swiss Cohort Study on Primary Biliary Cholangitis
Sep 14, 2016Research project in which biological material is sampled from humans and health-related personal data is collected for research.
Clinical Studies - Sep 14, 2016 - Sep 14, 2022
Automatically Closed
Project leader: Semela David
Members: Stillhard Roman
IDN-6556-14 NASH und Emricasan
Sep 14, 2016A Multicenter, Randomized, Double-Blind, Placebo- Controlled Trial of Emricasan, an Oral Caspase Inhibitor, in Subjects with Non-Alcoholic Steatohepatitis (NASH) Cirrhosis and Severe Portal Hypertension
Clinical Studies - Sep 14, 2016 - Sep 14, 2021
Aborted
Project leader: Semela David
Members: Alfter Christine