Unit
Gastroenterology/Hepatology
GASTRO · Dept. I
Entyvio PASS Study
Jul 28, 2016Entyvio (vedolizumab) long-term safety study: An international observational prospective cohort study comparing vedolizumab to other biologic agents in patients with ulcerative colitis or Crohn’s Disease. This is a prospective, observational, multi-...
Clinical Studies - Jul 28, 2016 - Jun 28, 2022
Automatically Closed
Project leader: Brand Stephan
Members: Dora Barbara, Knellwolf Christina, Sulz Michael, Krieger-Grübel Claudia
SASL 40 Swiss Cohort Study on Primar Sclerosing Cholangitis
Jun 1, 2016Research project in which biological material is sampled from humans and health-related personal data is collected for research.
Clinical Studies - Jun 1, 2016 - Sep 14, 2022
Automatically Closed
Project leader: Semela David
Members: Stillhard Roman
EFTR - Register
May 13, 2016Die endoskopische Vollwandresektion (endoscopic full thickness resection: EFTR) ist ein neuer therapeutischer und/oder diagnostischer Ansatz zur Behandlung von konventionell endoskopisch nicht angehbarer kolorektaler Neoplasien. Diese neue Technik...
Clinical Studies - May 13, 2016 - May 13, 2020
Completed
Project leader: Baumeler Stephan
Intercept 747-303 NASH and OCA
Mar 7, 2016A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Obeticholic Acid in Subjects with Nonalcoholic Steatohepatitis
Clinical Studies - Mar 7, 2016 - Mar 7, 2021
Automatically Closed
Project leader: Semela David
Members: Alfter Christine
Intercept 747-302 PBC und OCA
Mar 7, 2016“A Phase 3b, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study Evaluating the Effect of Obeticholic Acid on Clinical Outcomes in Subjects with Primary Biliary Cirrhosis”
Clinical Studies - Mar 7, 2016 - Mar 7, 2021
Automatically Closed
Project leader: Semela David
Members: Alfter Christine
SASl 36 The health burden of Primary Biliary Cirrhosis in Switzerland
Mar 7, 2016
Clinical Studies - Mar 7, 2016 - Sep 14, 2016
Completed
Project leader: Semela David
Members: Alfter Christine
Swiss Hepatitis B Cohort Study
Mar 7, 2016Swiss Hepatitis B Cohort Study
Fundamental Research - Mar 7, 2016 - Mar 7, 2016
Automatically Closed
Project leader: Semela David
Members: Alfter Christine, Zeuge Ulf
Evaluation der diagnostischen Genauigkeit und Sicherheit des Einsatzes bereits etablierter Ultraschall- und Magnetresonanz-Techniken (Elastographie, Multiparametrische Bildgebung) zur nicht-invasiven Diagnostik von Leber-/Milzerkrankungen im Vergleich zur simultanen perkutanen Leberbiopsie
Mar 7, 2016Evaluation CAP vs. Histologie Stephan Baumeler, Irina Bergamin Zusammenarbeit mit USZ Christoph Gubler und Michael Scharl
Clinical Studies - Mar 7, 2016 - Mar 7, 2020
Automatically Closed
Project leader: Semela David
Members: Alfter Christine
PCG-2/UCA
Mar 1, 2016Randomized, double-blind, double-dummy, placebo-controlled, Phase III clinical trial on the efficacy and safety of a 12-weeks add-on treatment with LT-02 (gastro-resistant phosphatidylcholine granules) vs. placebo in patients with ulcerative colitis...
Clinical Studies - Mar 1, 2016 - Dec 31, 2017
Aborted
Members: Dora Barbara, Knellwolf Christina, Sulz Michael, Krieger-Grübel Claudia
Abbvie M13-590 “A Randomized, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Adults with Chronic Hepatitis C Virus Genotype 1 Infection
Jan 2, 2016
Clinical Studies - Jan 2, 2016 - Mar 2, 2017
Completed
Project leader: Semela David
Members: Alfter Christine
Abbvie M13-594 A Randomized, Open-Label, Active-Controlled, Multicenter Study to Compare Efficacy and Safety of ABT-493/ABT-530 to Sofosbuvir Co-Administered with Ribavirin in Adults with Chronic Hepatitis C Virus Genotype 3 Infection
Jan 2, 2016
Clinical Studies - Jan 2, 2016 - Mar 2, 2017
Completed
Project leader: Semela David
Members: Alfter Christine
Evaluation of Controlled Attenuated Parameter (CAP) for Assessment of Liver Steatosis in an Unselected Population: a Single Center Real Life Experience
Dec 16, 2015Background & Aims: Controlled attenuated parameter (CAP) is a new parameter to assess steatosis of the liver, which is obtained together with elastography. Our aim was to assess the performance of CAP in an unselected population with different liver...
Clinical Studies - Dec 16, 2015 - Dec 16, 2017
Completed
Project leader: Baumeler Stephan
Members: Semela David, Bergamin Irina, Jochum Wolfram, Neuweiler Jörg
Liver metastasis in colorectal carcinoma: Accuracy of Contrast-enhanced ultrasound (CEUS) in comparison with computertomography on new diagnosed CRC with impact on therapy strategy?
Dec 1, 2015Background: Up to 20% of liver metastasis could be missed by CT according to the oncological staging in colorectal carcinoma Primary endpoint: Detection of colorectal liver metastasis (CRLM) – comparison of CEUS with CT (hypothesis CEUS with better s...
Clinical Studies - Dec 1, 2015 - Nov 1, 2018
Automatically Closed
Project leader: Sawatzki Mikael
Members: Alfter Christine, Semela David, Gueller Ulrich, Horber Daniel, Bergamin Irina
MERTK signalling in monocytes/macrophages in patients with liver disease
Nov 15, 2015Cirrhosis of the liver is a condition with a high mortality and raising prevalence worldwide. Infectious complications are highly frequent and independent predictors of outcome in patients with cirrhosis – being the leading cause of decompensation, ‘...
Fundamental Research - Nov 15, 2015 - Sep 30, 2019
Automatically Closed
Project leader: Bernsmeier Christine
Members: Semela David, Künzler-Heule Patrizia, Alfter Christine, Brenig Robert
GA289103/Gardenia
Jun 28, 2015GA29103: PHASE III, RANDOMIZED, MULTICENTER DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ETROLIZUMAB COMPARED WITH INFLIXIMAB IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS WHO ARE NAIVE TO TNF INHIBITORS
Clinical Studies - Jun 28, 2015 - Jun 28, 2020
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Sulz Michael, Semadeni Gian-Marco
OPTIMIS - Beobachtung der Behandlung mit oder ohne Nexavar von Patienten mit HCC nach erfolgter TACE und des Einschlusses des zeitlichen Beginns der nexavartherapie
Mar 30, 2015
Clinical Studies - Mar 30, 2015 - Sep 30, 2017
Completed
Members: Alfter Christine, Bernsmeier Christine, Künzler-Heule Patrizia, Semela David
Abbvie M14-423 An Open Label, Multicenter Study to Evaluate Long-Term Outcomes With ABT-450/Ritonavir/ABT-267 and ABT-333 With or Without Ribavirin in Adults With Genotyp 1 Chronic Hepatitis C Infection
Mar 26, 2015
Clinical Studies - Mar 26, 2015 - Mar 31, 2020
Automatically Closed
Project leader: Semela David
Members: Bernsmeier Christine, Künzler-Heule Patrizia, Stillhard Roman
Abbvie M 14-347
Mar 1, 2015A Multicenter, Open-Label Study to Evaluate the Long Term Efficacy, Safety, and Tolerability of Repeated Administration of Adalimumab in Subjects with Crohn's Disease
Clinical Studies - Mar 1, 2015 - Dec 1, 2017
Completed
Project leader: Borovicka Jan
Members: Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
Abbvie M14-033
Mar 1, 2015A Double-Blind, Randomized, Multicenter Study of Higher Versus Standard Adalimumab Dosing Regimens for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis This Phase 3 study design includes a Screening...
Clinical Studies - Mar 1, 2015 - Feb 1, 2018
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
ALERT
Feb 28, 2015VAlidation of an 8-‐item-‐questionnaire predictive for a positive CaLprotectin tEst and Real-‐life implemenTation in primary care to reduce diagnostic delay in inflammatory bowel disease
Clinical Studies - Feb 28, 2015 - Jan 30, 2017
Completed
Project leader: Borovicka Jan
Members: Dora Barbara, Sulz Michael