Projects
Search from 1147 projects:
1147 Project(s)
Comparison of discordant baseline imaging findings, reassessment of binary ischemic core evaluation and hypodensity mapping for functional outcome prediction in middle cerebral artery ischemic stroke using ASPECTS
Jan 1, 2024All subprojects focus on expanding the understanding of the emerging trend towards ubiquitously accessible and technically simpler imaging selection criteria for endovascular treatment based on native CT brainimaging in patients with acute ischemic s...
Clinical Studies - Jan 1, 2024 - Jan 1, 2026
Scheduled
Project leader: Dittrich Tolga
Prevalence of serous tubal intraepthelial carcinoma and signature lesions in fallopian tube specimens and PAP smear samples of breast and ovarian cancer patients
Dec 31, 2023«Proof-of-Concept Studie. Ziel ist das Entwickeln einer Methode zur Früherkennung von hochgradige seröse Ovarialkarzinom, insbesondere bei BRCA-mutierten Frauen. Hochgradiges seröses Ovarialkarzinom ist der häufigste Subtyp von Eierstockkrebs mit...
Fundamental Research - Dec 31, 2023 - Dec 31, 2024
Ongoing
Project leader: Hornung René
Members: Nemes Constanze, Su Elena
A single-arm phase II trial of the addition of niraparib to anti-PD-L1 antibody maintenance in patients with SLFN11-positive, extensive-disease small cell lung cancer.
Dec 21, 2023
Clinical Studies - Dec 21, 2023 - Dec 31, 2027
Ongoing
Project leader: Jörger Markus
Members: Quinter Janine, Radovanovic Suzana
OASIS – Optimierung der Antibiotikanutzung im stationären Setting durch Interprofessionelles Stewardship
Dec 1, 2023Zur Optimierung des Antibiotikaverbrauchs wurde am Kantonsspital St.Gallen ein Antimicrobial Stewardship Programm (ASP) eingeführt. Für die erfolgreiche Umsetzung braucht es die aktive Einbindung aller beteiligten Fachpersonen über den gesamten Verso...
Healthcare Research - Dec 1, 2023 - Aug 31, 2024
Automatically Closed
Project leader: Künzler-Heule Patrizia
Members: Kohler Philipp, Kuster Stefan, Ledergerber Katrin, Flury Domenica, Schoop Barbara, Nicca D
Carity Study
Dec 1, 2023CARITY: A targeted approach to ensuring CARe and ActivITY persistence in mid- to older-age persons during and after cardiac rehabilitation following a cardiovascular event or intervention
Clinical Studies - Dec 1, 2023 - Feb 1, 2025
Ongoing
Project leader: Buser Marc
Members: Vetsch Susanne
A Phase III, Randomized, Open-Label, Multicenter, Global Study of Volrustomig (MEDI5752) in Combination with Carboplatin plus Pemetrexed Versus Platinum plus Pemetrexed or Nivolumab plus Ipilimumab in Participants with Unresectable Pleural Mesothelioma (eVOLVE-Meso)
Nov 17, 2023Forscher suchen nach einer besseren Möglichkeit, fortgeschrittenes Pleuramesotheliom zu behandeln. Pleuramesotheliom ist eine Krebsart, die die Lungenschleimhaut befällt. Fortgeschritten bedeutet in der Regel, dass der Krebs nicht operativ behandelt...
Clinical Studies - Nov 17, 2023 - Dec 31, 2028
Ongoing
Project leader: Früh Martin
Members: Demmer-Steingruber Ruth, Quinter Janine
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy
Nov 3, 2023
Clinical Studies - Nov 3, 2023 - Dec 1, 2028
Ongoing
Project leader: Baumann Michael
Members: Harder Anja, Quinter Janine
A Phase 1, Open-Label, Multicenter Study of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
Oct 30, 2023
Clinical Studies - Oct 30, 2023 - Dec 31, 2026
Ongoing
Project leader: Jörger Markus
Members: Bürki Ramona, Quinter Janine
Vista Study
Oct 23, 2023prospective, observational, global, multicenter study: The objective of the VISTA Study is to evaluate the safety and performance of the Navitor valve in a realworld setting. This study is intended to satisfy post-market clinical follow-up require...
Clinical Studies - Oct 23, 2023 - Oct 30, 2030
Ongoing
Project leader: Haager Philipp K.
Members: Vetsch Susanne
A double-blind randomised phase III trial evaluating the efficacy of ADT +/- darolutamide in de novo metastatic prostate cancer patients with vulnerable functional ability and not elected for docetaxel or androgen receptor targeted agents
Oct 18, 2023
Clinical Studies - Oct 18, 2023 - Dec 31, 2028
Ongoing
Project leader: Fischer Stefanie
Members: Harder Anja, Quinter Janine
Cryptogenic Etiology in Young Adults with Stroke or Transient Ischemic Attack
Oct 2, 2023Explorierung der Charakteristika und klinischen Outcomes «junger» (18-55 J.) Patient:innen mit akutem ischämischen Schlaganfall (inkl. transient ischämischer Attacke) mit fehlender fassbarer Schöaganfallätiologie (trotz erfolgter Basisabklärung; Pati...
Clinical Studies - Oct 2, 2023 - Dec 31, 2024
Ongoing
Project leader: Dittrich Tolga, De Marchis Gian Marco
Members: Schneider Thomas
The Selution DeNovo Study
Sep 28, 2023A prospective, randomized, multicenter, international, open, clinical study in which the SELUTION DEB strategy was compared with the DES strategy. Study objectives: 1) At 1 year, to demonstrate non-inferiority for TVF of a treatment strategy wi...
Clinical Studies - Sep 28, 2023 - Sep 28, 2028
Ongoing
Project leader: Rigger Johannes
Members: Meier Jessica, Schneider Irene
Early protected full weight-bearing vs. partial weight-bearing after surgical fixation of unstable ankle fractures, monitored with bio-feedback insoles. A single blinded randomized controlled study
Sep 1, 2023adhere to instructions concerning weight-bearing. The purpose of this study is to compare the postoperative results after ORIF with a PWB protocol versus an early FWB protocol. But in addition, we will measure every patient’s actual load by the mean...
Clinical Studies - Sep 1, 2023 - Oct 31, 2026
Scheduled
Project leader: Potocnik Primoz, Toepfer Andreas
Targeting des Immunoproteasoms in vivo
Aug 1, 2023Proteasome sind vielversprechende Angriffspunkte für Medikamente bei Krebserkrankungen. Mehrere Proteasom-Inhibitoren werden bereits klinisch zur Behandlung des multiplen Myeloms (MM) eingesetzt. Aktuelle in der Klinik eingesetzte Proteasom-Inhibitor...
Fundamental Research - Aug 1, 2023 - Dec 31, 2023
Automatically Closed
Project leader: Driessen Christoph
Members: Mendez Lopez Max, Besse Lenka
Immunopathological pathways underlying myocarditis and inflammatory cardiomyopathy – an exploratory study
Jul 24, 2023The main hypothesis underlying the suggested research program is that autoimmune CD4+ T cells cross-reacting with bacteria in the intestinal microbiome drive not only the development of acute cardiac inflammation but maintain the perpetuation of infl...
Clinical Studies - Jul 24, 2023 - Jul 24, 2024
Automatically Closed
Project leader: Ludewig Burkhard
Members: Rickli Hans, Maeder Micha, Vetsch Susanne
A Randomized, Open-label, Phase 3 Study of Tarlatamab Compared With Standard of Care in Subjects with Relapsed Small Cell Lung Cancer After Platinum-based First Line chemotherapy (DeLLphi-304)
Jul 17, 2023
Clinical Studies - Jul 17, 2023 - Dec 31, 2025
Ongoing
Project leader: Früh Martin
Members: Hutter Franziska, Quinter Janine
Retrospective and prospective registry of patients with metastatic NSCLC harboring typical and atypical EGFR mutations
Jul 3, 2023
Clinical Studies - Jul 3, 2023 - Dec 31, 2030
Ongoing
Project leader: Früh Martin
Members: Radovanovic Suzana, Müller Fiona
Leptomeningeal Collaterals in INtracErebral Hemorrhage: Association with Hematoma Size and Expansion
Jul 3, 2023Die intrazerebrale Blutung (ICB) ist eine verheerende Form des Schlaganfalls, die mit einer hohen Morbidität und Mortalität einhergeht. Die Ausdehnung des Hämatoms trägt wesentlich zu den schlechten Ergebnissen bei ICB-Patienten bei und gilt als beei...
Clinical Studies - Jul 3, 2023 - Jan 1, 2025
Ongoing
Project leader: Dittrich Tolga, De Marchis Gian Marco
Members: Zell Daniel
Meaningful Patient and Public Involvement in the SHCS: A methods review and mixed-method study
Jul 1, 2023
Clinical Studies - Jul 1, 2023 - Oct 31, 2024
Ongoing
Project leader: Notter Julia
Members: Jackson-Perry David
Swiss Cardiac Amyloidosis Registry
Jul 1, 2023The aim of the Swiss-CARE registry is a comprehensive collection of clinical data and a follow-up of patients diagnosed with cardiac amyloidosis. Patients with and without therapy will be included in the registry. This will allow us to better under...
Register - Jul 1, 2023 - Jul 1, 2033
Ongoing
Project leader: Ehl Niklas
Members: Schneider Irene