Prof. Dr. Burkhard Ludewig
Head, Institute of Immunobiology
Head, Medical Research Center
Head of clinic/institute/center
Medizinisches Forschungszentrum, Institute of Immunobiology · Management
Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway
Kumar V, Scandella E, Danuser R, Onder L, Nitschké M, Fukui Y, Halin C, Ludewig B, Stein J. Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway. Blood 2010; 115:4725-33.
Jun 10, 2010Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway
Jun 10, 2010Blood 2010; 115:4725-33
Kumar Varsha, Scandella Elke, Danuser Renzo, Onder Lucas, Nitschké Maximilian, Fukui Yoshinori, Halin Cornelia, Ludewig Burkhard, Stein Jens V
Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice
Lang P, Zinkernagel R, Ohashi P, Häussinger D, Harris N, Hengartner H, Ludewig B, Kalinke U, Van Rooijen N, Cervantes-Barragan L, Kulawik A, Meryk A, Krings C, Gailus N, Borkens S, Scheu S, Honke N, Recher M, Lang K. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology 2010; 52:25-32.
Mar 1, 2010Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice
Mar 1, 2010Hepatology 2010; 52:25-32
Lang Philipp A, Zinkernagel Rolf M, Ohashi Pamela S, Häussinger Dieter, Harris Nicola, Hengartner Hans, Ludewig Burkhard, Kalinke Ulrich, Van Rooijen Nico, Cervantes-Barragan Luisa, Kulawik Andreas, Meryk Andreas, Krings Caroline, Gailus Nicole, Borkens Stephanie, Scheu Stefanie, Honke Nadine, Recher Mike, Lang Karl S
IFN-gamma-receptor signaling ameliorates transplant vasculopathy through attenuation of CD8+ T-cell-mediated injury of vascular endothelial cells.
Bolinger B, Engeler D, Krebs P, Miller S, Firner S, Hoffmann M, Palmer D, Restifo N, Tian Y, Clavien P, Ludewig B. IFN-gamma-receptor signaling ameliorates transplant vasculopathy through attenuation of CD8+ T-cell-mediated injury of vascular endothelial cells. Eur J Immunol 2010; 40:733-43.
Mar 1, 2010IFN-gamma-receptor signaling ameliorates transplant vasculopathy through attenuation of CD8+ T-cell-mediated injury of vascular endothelial cells.
Mar 1, 2010Eur J Immunol 2010; 40:733-43
Bolinger Beatrice, Engeler Daniel, Krebs Philippe, Miller Simone, Firner Sonja, Hoffmann Matthias, Palmer Douglas C, Restifo Nicholas P, Tian Yinghua, Clavien Pierre-Alain, Ludewig Burkhard
Liposome-based vaccines
Schwendener R, Ludewig B, Cerny A, Engler O. Liposome-based vaccines. Methods in molecular biology (Clifton, N.J.) 2010; 605:163-75.
Jan 1, 2010Liposome-based vaccines
Jan 1, 2010Methods in molecular biology (Clifton, N.J.) 2010; 605:163-75
Schwendener Reto A, Ludewig Burkhard, Cerny Andreas, Engler Olivier
A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections
Bocharov G, Züst R, Cervantes-Barragan L, Luzyanina T, Chiglintsev E, Chereshnev V, Thiel V, Ludewig B. A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections. PLoS Pathog 2010; 6:e1001017.
Jan 1, 2010A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections
Jan 1, 2010PLoS Pathog 2010; 6:e1001017
Bocharov Gennady, Züst Roland, Cervantes-Barragan Luisa, Luzyanina Tatyana, Chiglintsev Egor, Chereshnev Valery A, Thiel Volker, Ludewig Burkhard
Hematopoietic cell-derived interferon controls viral replication and virus-induced disease
Lang P, Ohashi P, Ludewig B, Honda K, Bergthaler A, Flatz L, Pellegrini M, Recher M, Navarini A, Verschoor A, Cervantes-Barragan L, Lang K. Hematopoietic cell-derived interferon controls viral replication and virus-induced disease. Blood 2009; 113:1045-52.
Jan 29, 2009Hematopoietic cell-derived interferon controls viral replication and virus-induced disease
Jan 29, 2009Blood 2009; 113:1045-52
Lang Philipp A, Ohashi Pamela S, Ludewig Burkhard, Honda Kenya, Bergthaler Andreas, Flatz Lukas, Pellegrini Marc, Recher Mike, Navarini Alexander A, Verschoor Admar, Cervantes-Barragan Luisa, Lang Karl S
Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection
Cervantes-Barragan L, Kalinke U, Züst R, König M, Reizis B, López-Macías C, Thiel V, Ludewig B. Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection. Journal of immunology (Baltimore, Md. : 1950) 2009; 182:1099-106.
Jan 15, 2009Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection
Jan 15, 2009Journal of immunology (Baltimore, Md. : 1950) 2009; 182:1099-106
Cervantes-Barragan Luisa, Kalinke Ulrich, Züst Roland, König Martin, Reizis Boris, López-Macías Constantino, Thiel Volker, Ludewig Burkhard
TLR2 and TLR4 signaling shapes specific antibody responses to Salmonella typhi antigens
Cervantes-Barragan L, Gil Cruz C, Pastelin-Palacios R, Lang K, Isibasi A, Ludewig B, López-Macías C. TLR2 and TLR4 signaling shapes specific antibody responses to Salmonella typhi antigens. Eur J Immunol 2009; 39:126-35.
Jan 1, 2009TLR2 and TLR4 signaling shapes specific antibody responses to Salmonella typhi antigens
Jan 1, 2009Eur J Immunol 2009; 39:126-35
Cervantes-Barragan Luisa, Gil Cruz Cristina, Pastelin-Palacios Rodolfo, Lang Karl S, Isibasi Armando, Ludewig Burkhard, López-Macías Constantino
Immunopathological basis of lymphocytic choriomeningitis virus-induced chorioretinitis and keratitis
Zinkernagel M, Bolinger B, Krebs P, Onder L, Miller S, Ludewig B. Immunopathological basis of lymphocytic choriomeningitis virus-induced chorioretinitis and keratitis. Journal of virology 2009; 83:159-66.
Jan 1, 2009Immunopathological basis of lymphocytic choriomeningitis virus-induced chorioretinitis and keratitis
Jan 1, 2009Journal of virology 2009; 83:159-66
Zinkernagel Martin S, Bolinger Beatrice, Krebs Philippe, Onder Lucas, Miller Simone, Ludewig Burkhard
Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome
Birnberg T, Reizis B, Riethmacher D, Brockschnieder D, Ludewig B, Brenner O, Krauthgamer R, Makia D, Cervantes-Barragan L, Caton M, Sapoznikov A, Bar-On L, Jung S. Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome. Immunity 2008; 29:986-97.
Dec 1, 2008Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome
Dec 1, 2008Immunity 2008; 29:986-97
Birnberg Tal, Reizis Boris, Riethmacher Dieter, Brockschnieder Damian, Ludewig Burkhard, Brenner Ori, Krauthgamer Rita, Makia Divine, Cervantes-Barragan Luisa, Caton Michele L, Sapoznikov Anita, Bar-On Liat, Jung Steffen
Mouse hepatitis virus liver pathology is dependent on ADP-ribose-1''-phosphatase, a viral function conserved in the alpha-like supergroup
Eriksson K, Cervantes-Barragan L, Ludewig B, Thiel V. Mouse hepatitis virus liver pathology is dependent on ADP-ribose-1''-phosphatase, a viral function conserved in the alpha-like supergroup. Journal of virology 2008; 82:12325-34.
Dec 1, 2008Mouse hepatitis virus liver pathology is dependent on ADP-ribose-1''-phosphatase, a viral function conserved in the alpha-like supergroup
Dec 1, 2008Journal of virology 2008; 82:12325-34
Eriksson Klara Kristin, Cervantes-Barragan Luisa, Ludewig Burkhard, Thiel Volker
Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence
Junt T, Scandella E, Ludewig B. Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence. Nature reviews. Immunology 2008; 8:764-75.
Oct 1, 2008Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence
Oct 1, 2008Nature reviews. Immunology 2008; 8:764-75
Junt Tobias, Scandella Elke, Ludewig Burkhard
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice
Kang T, Oh G, Scandella E, Bolinger B, Ludewig B, Kovalenko A, Wallach D. Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. Journal of immunology (Baltimore, Md. : 1950) 2008; 181:2522-32.
Aug 15, 2008Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice
Aug 15, 2008Journal of immunology (Baltimore, Md. : 1950) 2008; 181:2522-32
Kang Tae-Bong, Oh Gi-Su, Scandella Elke, Bolinger Beatrice, Ludewig Burkhard, Kovalenko Andrew, Wallach David
[Uro-oncological research from the laboratory and clinical practice]
Engeler D, Ludewig B, Schmid H. [Uro-oncological research from the laboratory and clinical practice]. Der Urologe. Ausg. A 2008; 47:978-81.
Aug 1, 2008[Uro-oncological research from the laboratory and clinical practice]
Aug 1, 2008Der Urologe. Ausg. A 2008; 47:978-81
Engeler Daniel, Ludewig Burkhard, Schmid Hans-Peter
Aggravation of viral hepatitis by platelet-derived serotonin
Lang P, Bader M, Graf R, Clavien P, Hegazy A, Löhning M, Harris N, Ohashi P, Hengartner H, Zinkernagel R, Odermatt B, Merkler D, Contaldo C, Georgiev P, El-Badry A, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Lang K. Aggravation of viral hepatitis by platelet-derived serotonin. Nature medicine 2008; 14:756-61.
Jul 1, 2008Aggravation of viral hepatitis by platelet-derived serotonin
Jul 1, 2008Nature medicine 2008; 14:756-61
Lang Philipp A, Bader Michael, Graf Rolf, Clavien Pierre-Alain, Hegazy Ahmed N, Löhning Max, Harris Nicola L, Ohashi Pamela S, Hengartner Hans, Zinkernagel Rolf M, Odermatt Bernhard, Merkler Doron, Contaldo Claudio, Georgiev Panco, El-Badry Ashraf Mohammad, Recher Mike, Kurrer Michael, Cervantes-Barragan Luisa, Ludewig Burkhard, Calzascia Thomas, Bolinger Beatrice, Lang Karl S
Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone
Scandella E, Junt T, Luther S, Finke D, Littman D, Favre S, Miller S, Lattmann E, Bolinger B, Ludewig B. Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone. Nature immunology 2008; 9:667-75.
Jun 1, 2008Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone
Jun 1, 2008Nature immunology 2008; 9:667-75
Scandella Elke, Junt Tobias, Luther Sanjiv A, Finke Daniela, Littman Dan R, Favre Stéphanie, Miller Simone, Lattmann Evelyn, Bolinger Beatrice, Ludewig Burkhard
Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen
Bolinger B, Clavien P, Restifo N, Palmer D, Miller S, Scandella E, Engeler D, Tian Y, Krebs P, Ludewig B. Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen. Blood 2008; 111:4588-95.
May 1, 2008Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen
May 1, 2008Blood 2008; 111:4588-95
Bolinger Beatrice, Clavien Pierre-Alain, Restifo Nicholas P, Palmer Douglas C, Miller Simone, Scandella Elke, Engeler Daniel, Tian Yinghua, Krebs Philippe, Ludewig Burkhard
Chronic immune reactivity against persisting microbial antigen in the vasculature exacerbates atherosclerotic lesion formation
Krebs P, Scandella E, Bolinger B, Engeler D, Miller S, Ludewig B. Chronic immune reactivity against persisting microbial antigen in the vasculature exacerbates atherosclerotic lesion formation. Arteriosclerosis, thrombosis, and vascular biology 2007; 27:2206-13.
Oct 1, 2007Chronic immune reactivity against persisting microbial antigen in the vasculature exacerbates atherosclerotic lesion formation
Oct 1, 2007Arteriosclerosis, thrombosis, and vascular biology 2007; 27:2206-13
Krebs Philippe, Scandella Elke, Bolinger Beatrice, Engeler Daniel, Miller Simone, Ludewig Burkhard
Mathematical modelling of the antiviral type I interferon response
Bocharov G, Eriksson K, Ludewig B, Cervantes-Barragan L (2007). Mathematical modelling of the antiviral type I interferon response.
Sep 9, 2007Mathematical modelling of the antiviral type I interferon response
Sep 9, 20072nd Conference Foundations of Systems Biology in Engineering
Bocharov Gennady, Eriksson Klara-Kristin, Ludewig Burkhard, Cervantes-Barragan Luisa
Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines
Züst R, Cervantes-Barragan L, Kuri T, Blakqori G, Weber F, Ludewig B, Thiel V. Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. PLoS pathogens 2007; 10;3(8):e109:1062-1072.
Aug 1, 2007Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines
Aug 1, 2007PLoS pathogens 2007; 10;3(8):e109:1062-1072
Züst Roland, Cervantes-Barragan Luisa, Kuri Thomas, Blakqori Gjon, Weber Friedemann, Ludewig Burkhard, Thiel Volker