To evaluate the continued safety and performance of the Reva Fantom Sirolismus-Eluting Bioresorbable Coronary Scaffold in nativ coronary arteries that includes incorporation of a deformable expansion technologgy and an enhanced scaffold material (Tyr...

Clinical Studies - May 6, 2024 - Jun 30, 2030

Ongoing

Project leader: Rigger Johannes
Members: Fink Karin, Schneider Irene

A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) with apixaban for the preve...

Clinical Studies - Jun 1, 2023 - Jun 30, 2024

Completed

Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne

Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death and treatment of acute myocardial infarction in subjec...

Clinical Studies - Jan 10, 2022 - Jan 14, 2026

Ongoing

Project leader: Maeder Micha
Members: Vetsch Susanne, Fink Karin

This study is a single armed, prospective, multi-center, observational study Planned: up to 40 study sites in the EU and selected non-EU-countries

Clinical Studies - Oct 21, 2021 - Dec 31, 2026

Ongoing

Project leader: Rigger Johannes
Members: Vetsch Susanne, Fink Karin

Contemporary findings from the ongoing Swiss-AF cohort study (2’415 patients with atrial fibrillation (AF) enrolled, 1’760 patients with available brain imaging) showed that patients with AF have a high burden of cerebral infarcts and other brain les...

Clinical Studies - Jun 17, 2021 - Jun 17, 2025

Ongoing

Project leader: Ammann Peter
Members: Fink Karin

Treatment patterns and Outcomes across the disease Continuum in patients with CAD and/or PAD The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or sym...

Clinical Studies - Jul 14, 2020 - Apr 14, 2023

Completed

Project leader: Rickli Hans
Members: Fink Karin

Post-market registry to evaluate the safety and efficacy of the Supraflex Cruz™ sirolimus-eluting coronary stent system in the treatment of all-comer patients with coronary artery disease

Clinical Studies - Jul 13, 2020 - Dec 31, 2022

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene, Fink Karin

Health consequences of the Burden of atrial fibrillation The added information of measuring AF burden and measuring cardiac dimensions and function in an AF patient population where brain MRIs are available, could provide further evidence toward...

Clinical Studies - Apr 6, 2020 - Apr 6, 2024

Completed

Project leader: Ammann Peter
Members: Altmann David, Fink Karin

Multicenter, randomized, active comparator-controlled, double-blind, double-dummy, parallel group, dose-finding Phase 2 study to compare the safety of the oral FXIa inhibitor BAY 2433334 to apixaban in patients with atrial fibrillation Primary Safet...

Clinical Studies - Jan 21, 2020 - Dec 7, 2021

Completed

Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne

The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or symptomatic peripheral artery disease (PAD) treated with rivaroxaban 2.5 mg[BID] for the prevention of...

Clinical Studies - Nov 19, 2019 - Dec 21, 2021

Completed

Project leader: Rickli Hans
Members: Fink Karin

Takotsubo Cardiomyopathy, or broken heart syndrome, is a recently described acquired form of cardiomyopathy whose pathophysiology is not well understood and particularly affects postmenopausal women. The exact mechanism is still unclear and large p...

Clinical Studies - Apr 1, 2018 - Dec 31, 2030

Ongoing

Project leader: Jörg Lucas
Members: Fink Karin, Schneider Irene

Study Hypothesis: In patients with evidence of device-detected sub-clinical atrial fibrillation (SCAF) and additional risk factors for stroke, treatment with apixaban compared with aspirin will reduce the risk of the composite of stroke and systemic...

Clinical Studies - Apr 1, 2016 - Jan 1, 2026

Completed

Project leader: Ammann Peter
Members: Gemperle Michaela, Brenner Roman, Fink Karin, Vetsch Susanne

To increase our knowledge on structural brain damage and its changes over time in patients with AF 2. To gain additional insights on the incidence and underlying mechanisms of cognitive decline in patients with AF 3. To improve long term risk pre...

Clinical Studies - Jun 12, 2014 - Jan 1, 2032

Ongoing

Project leader: Ammann Peter
Members: Altmann David, Gemperle Michaela, Kopp Sebastian, Fink Karin, Brenner Roman, Vetsch Susanne

Vorhofflimmern ist die häufigste Herzrhythmusstörung in der Bevölkerung. Die genaue Entstehung und vor allem das Fortschreiten dieser Erkrankung sind jedoch trotz vieler Jahre intensiver Forschung nur unvollständig geklärt. Der Funktionszustand des H...

Clinical Studies - Jun 1, 2010 - Jan 1, 2032

Ongoing

Project leader: Ammann Peter
Members: Gemperle Michaela, Schneider Irene, Fink Karin

The AMIS Plus national registry collects and analyzes data on patients with acute coronary syndrome (acute myocardial infarction, unstable angina and minimal necrosis) in Switzerland in the pre-admission, hospital and follow-up phases. Emphasis is pl...

Clinical Studies - Jan 1, 1997 - Dec 31, 2030

Ongoing

Project leader: Rickli Hans
Members: Schneider Irene, Fink Karin