Prof. Dr.med. Hans Rickli
chief physician
Kardiologie · Dept. I
OCEAN
May 1, 2023A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein (a).
Clinical Studies - May 1, 2023 - Dec 31, 2024
Scheduled
Project leader: Bilz Stefan
Members: Räss Andrea, Rickli Hans, Vetsch Susanne
Oceanic AF
Apr 1, 2023A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) with apixaban for the preve...
Clinical Studies - Apr 1, 2023 - Jun 30, 2026
Scheduled
Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne
AMGEN202100057
May 1, 2022A Multicenter, Cross-sectional Study to Characterize the Distribution of Lipoprotein(a) Levels Among Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD). The purpose of the study is to characterize the distribution o...
Clinical Studies - May 1, 2022 - Mar 31, 2023
Automatically Closed
Project leader: Rickli Hans
Members: Vetsch Susanne, Bilz Stefan, Räss Andrea
CATCH - Cascade genetic testing of familial hypercholesterolemia: the CATCH multicenter randomized controlled trial
Dec 15, 2020To test in a multicenter open-label randomized controlled trial across Switzerland whether a cascade screening programme for FH, in comparison with usual care, will increase the detection rate of FH within families. The primary outcome will be the d...
Clinical Studies - Dec 15, 2020 - Dec 30, 2023
Ongoing
Project leader: Rickli Hans
Members: Vetsch Susanne, Schneider Irene
SwissSCAD
Oct 1, 2020The primary aim is to gather observational data from consecutive SCAD patients in Switzerland, in order to establish a National Swiss Registry (SwissSCAD). SCAD is a poorly understood condition, affecting young patients and is associated with major...
Clinical Studies - Oct 1, 2020 - Dec 31, 2030
Ongoing
Project leader: Rickli Hans
Members: Schneider Irene
XATOC – Xarelto + Acetylsalicylic Acid
Jul 14, 2020Treatment patterns and Outcomes across the disease Continuum in patients with CAD and/or PAD The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or sym...
Clinical Studies - Jul 14, 2020 - Jul 14, 2024
Ongoing
Project leader: Rickli Hans
Members: Fink Karin
PACIFIC AF
Jan 21, 2020Multicenter, randomized, active comparator-controlled, double-blind, double-dummy, parallel group, dose-finding Phase 2 study to compare the safety of the oral FXIa inhibitor BAY 2433334 to apixaban in patients with atrial fibrillation Primary Safet...
Clinical Studies - Jan 21, 2020 - Dec 7, 2021
Completed
Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne
XATOA – Xarelto + Acetylsalicylic Acid: Treatment
Nov 19, 2019The study aims to collect real-world data on treatment patterns and decision points for treatment in patients with coronary artery disease (CAD) or symptomatic peripheral artery disease (PAD) treated with rivaroxaban 2.5 mg[BID] for the prevention of...
Clinical Studies - Nov 19, 2019 - Dec 21, 2021
Completed
Project leader: Rickli Hans
Members: Fink Karin
AEGIS II_CSL112_3001
Aug 7, 2019A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome
Clinical Studies - Aug 7, 2019 - Aug 30, 2020
Aborted
Project leader: Rickli Hans
Members: Vetsch Susanne
OPTIMIZE
Apr 8, 2019Prospektive nicht-interventionelle Studie zur optimierten Behandlung einer therapierefraktären Hypercholesterinämie bei Patienten mit heterozygoter familiärer Hypercholesterinämie oder klinisch manifester atherosklerotischer kardiovaskulärer Erkranku...
Clinical Studies - Apr 8, 2019 - Jan 15, 2021
Completed
Project leader: Rickli Hans
Members: Gemperle Michaela
DPF Coro - Entwicklung einer diagnostischen Probabilitätsfunktion (DPF) bei Patienten mit rezidivierenden Thoraxschmerzen zur Schätzung der Wahrscheinlichkeit einer relevanten koronaren Herzkrankheit
Feb 1, 2019Ziele: Aus den klinischen Daten (Anamnese, körperliche Untersuchung und einem der Ischämietests [Ergometrie, Stress-Echo, Stress MRI) wird mit einer logistischen Regression eine Wahrscheinlichkeits-funktion abgeleitet. Als Referenzuntersuchung gelten...
Clinical Studies - Feb 1, 2019 - Mar 31, 2022
Completed
Project leader: Rickli Hans
Members: Schneider Irene
ENTRUST DSE-EDO-01-15-EU
Jul 7, 2017Beurteilung der Sicherheit und Wirksamkeit eines Edoxabanbasierten , verglichen mit einem Vitamin-K-Antagonist-basierten, antithrombotischen Therapieregimes nach einer erfolgreichen perkutanen Koronarintervention (PCI) mit Stent-Implantation, bei Pat...
Clinical Studies - Jul 7, 2017 - Jul 7, 2021
Completed
Project leader: Rickli Hans
Members: Gemperle Michaela
ECARA
Jun 16, 2017Explore Clinical Utility of Evolocumab in Combination with an e-Health System: Swiss Prospective Observational Study in Patients with clinical Atherosclerotic Cardiovascular Disease (ASCVD) (ECARA)
Clinical Studies - Jun 16, 2017 - Dec 1, 2019
Completed
Project leader: Rickli Hans
Members: Gemperle Michaela
GLORIA -AF
Feb 14, 2014GLORIA-AF: Global Registry on Long-Term Oral Anti-thrombotic Treatment in Patients with Atrial Fibrillation (Phase II/III – India and Switzerland) International, multicenter, prospective observational study for patients with newly diagnosed non-valvu...
Clinical Studies - Feb 14, 2014 - Nov 30, 2019
Completed
Project leader: Rickli Hans
AMG 145 20120153 GLAGOV
Jan 9, 2014Double-Blind, Randomized, Multi-Center, Placebo-Controlled, Parallel Group Study to Determine the Effects of Evolocumab (AMG 145) Treatment on Atherosclerotic Disease Burden As Measured By Intravascular Ultrasound in Subjects Undergoing Coronary Cath...
Clinical Studies - Jan 9, 2014 - Jan 9, 2018
Completed
Project leader: Rickli Hans
Members: Weilenmann Daniel, Gemperle Michaela, Rigger Johannes
AMG 145 20120138 OSLER
Sep 20, 2013A Multicenter Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of AMG 145 Study Phase: 3 Indication: Primary hyperlipidemia and mixed dyslipidemia Primary Objective: To characterize the safety and tolerability of long-ter...
Clinical Studies - Sep 20, 2013 - Sep 20, 2017
Completed
Project leader: Rickli Hans
Members: Gemperle Michaela, Rigger Johannes
BIOHELIX II : The treatment of coronary artery lesions using the PRO-Kinetic Energy Cobalt-Chromium, Bare-Metal Stent
May 24, 2013Die Behandlung von koronaren Läsionen mit PRO-Kinetic Energy Kobalt-Chrom Metall Stent (BIOHELIX II) Das primäre Ziel dieser Studie ist der Nachweis der klinischen Leistungsfähigkeit des PRO-Kinetic Energy Stents bei Patienten mit Atherosklerose in...
Clinical Studies - May 24, 2013 - May 24, 2017
Aborted
Project leader: Rickli Hans
Members: Schneider Irene
AMG 145 20110115 LAPLACE
Apr 1, 2013A Double-blind, Randomized, Placebo and Ezetimibe Controlled, Multicenter Study to Evaluate Safety, Tolerability and Efficacy of AMG 145 on LDL-C in Combination With Statin Therapy in Subjects With Primary Hypercholesterolemia and Mixed Dyslipidemia;
Clinical Studies - Apr 1, 2013 - Mar 3, 2014
Completed
Project leader: Rickli Hans
Members: Schefer Mirjam, Vollenbroich Rene
ORIGINALE
Nov 19, 2012Importance of Long-Term Follow-up of the ORIGIN Participants, the ORIGINALE (ORIGIN and Legacy Effects) Study
Clinical Studies - Nov 19, 2012 - Nov 19, 2016
Completed
Project leader: Brändle Michael
Members: Rickli Hans, Gemperle Michaela
EVITA-RAID-HF Register
May 14, 2012Evidence based treatment in heart failure (EVITA-HF) mit Teilprojekt Registry analysis of iron deficiency in heart failure (RAID-HF).
Clinical Studies - May 14, 2012 - Dec 31, 2016
Completed
Project leader: Rickli Hans
Members: Maeder Micha, Gall Christian, Gemperle Michaela