Projects
Search from 1140 projects:
1140 Project(s)
Deep immune cell phenotyping in patients suffering from HPV-positive tonsillar squamous cell carcinoma
Nov 4, 2022
Fundamental Research - Nov 4, 2022 - Dec 31, 2023
Automatically Closed
Project leader: Ludewig Burkhard
Members: Stanossek Yves
VICTORION Real
Nov 1, 2022
Clinical Studies - Nov 1, 2022 - Mar 31, 2027
Ongoing
Project leader: Bilz Stefan
Members: Sigrist Sarah, Räss Andrea
A Phase 1 Study to Investigate the Safety, Pharmacokinetics, and Efficacy of Tinostamustine, a Novel Alkylating and Deacetylase Inhibiting Molecule, as Adjuvant Treatment in Patients with Newly Diagnosed Unmethylated MGMT-promoter Glioblastoma
Oct 10, 2022Diese Studie untersucht, wie sicher, verträglich und wirksam Tinostamustin (EDO-S101) für die Behandlung Ihrer Krebserkrankung ist. Tinostamustin ist ein neues Molekül, dass für die Behandlung verschiedener Krebsarten untersucht wird, darunter Blutkr...
Clinical Studies - Oct 10, 2022 - Jun 30, 2024
Completed
Project leader: Hundsberger Thomas
Members: Aeschbacher Anette, Frehner Jan
A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA versus Bortezomib, Lenalidomide, and Dexamethasone (VRd) followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants with Newly Diagnosed Multiple Myeloma for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy
Sep 16, 2022Es handelt sich um eine offene weltweit durchgeführte Studie zur Beurteilung, ob eine Einleitungstherapie (Induktion) mit VRd gefolgt von einer einmaligen Gabe Cilta-Cel im Vergleich zur VRd-Induktion gefolgt von Rd-Erhaltungstherapie einen Wirksamke...
Clinical Studies - Sep 16, 2022 - Dec 31, 2032
Ongoing
Project leader: Lehmann Thomas
Members: Donno Monica, Quinter Janine
A Randomized, Open-label, Phase 3 Study of Sacituzumab GovitecanVersus Treatment of Physician’s Choice in Patients With Previously Untreated, Locally Advanced, Inoperable or Metastatic Triple-Negative Breast Cancer Whose Tumors Do Not Express PD-L1 or in Patients Previously Treated With Anti-PD-(L)1 Agents in theEarly Setting Whose Tumors do Express PD-L1
Sep 9, 2022In dieser Studie wird ein experimentelles Medikament namens Sacituzumab Govitecan bei bisher unbehandeltem, fortgeschrittenem dreifach-negativem Brustkrebs (TNBC) untersucht. Fortgeschrittener TNBC ist definiert als TNBC, der nicht durch eine Operati...
Clinical Studies - Sep 9, 2022 - Dec 31, 2026
Ongoing
Project leader: Huober Jens
Members: Scherrer Julia, Quinter Janine
CATALYM CTL-002-001 A PHASE 1/2, FIRST-IN-HUMAN, TWO-PART, OPEN-LABEL CLINICAL TRIAL OF INTRAVENOUS ADMINISTRATION OF CTL-002 GIVEN AS MONOTHERAPY AND/OR IN COMBINATION WITH AN ANTI-PD-1 CHECKPOINT INHIBITOR IN SUBJECTS WITH ADVANCED-STAGE, RELAPSED/REFRACTORY SOLID TUMORS
Sep 2, 2022Diese klinische Studie wird durchgeführt, um ein neues Prüfpräparat mit der Bezeichnung "CTL-002" zu testen. CTL-002 gehört zu einer Klasse von Medikamenten, die als monoklonale Antikörper bezeichnet werden. Antikörper sind vom Immunsystem hergestell...
Clinical Studies - Sep 2, 2022 - Sep 8, 2030
Completed
Project leader: Jörger Markus
Members: Bürki Ramona, Quinter Janine
(18)RoSMA-18 Studie mit Zürich und Bern
Sep 1, 2022Das Universitätsspital Bem führt im Rahmen der Studie an zwei verschiedenen Terminen bei 20 ALS Patienten des Kantonsspitals St.Gallen und an zwei Termin bei gesunden Probanden des Kantonsspitals St.Gallen ein PET des Gehirns und des Rückenmarks na...
Clinical Studies - Sep 1, 2022 - Dec 31, 2024
Ongoing
Project leader: Weber Markus
Phase 3 Study of Teclistamab in Combination with Lenalidomide versus Lenalidomide Alone in Participants with Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation
Aug 23, 2022Diese Studie soll die Behandlungsmöglichkeiten des von den Plasmazellen des Knochenmarks ausgehende Krebserkrankung weiter verbessern. Das so genannte Multiple Myelom wird durch ein Wachstum von abnormalen Plasmazellen im Knochenmark verursacht. Es s...
Clinical Studies - Aug 23, 2022 - Aug 24, 2030
Ongoing
Project leader: Silzle Tobias
Members: Scherrer Julia, Frehner Jan
Athena-SSc-ILD-Study
Aug 23, 2022A double blind, randomized, placebo-controlled study to evaluate the efficacy and safety of PRA023 in Subject with Systemic Sclerosis associated with interstitial Lung Disease.
Clinical Studies - Aug 23, 2022 - Aug 23, 2024
Ongoing
Project leader: Rubbert-Roth Andrea
Members: Peischl Riana, Peischl Shirin, Bartz-Batliner Mira, Hutz Carina Liane, Schmiedeberg Kristin
SPECTA: Screening Cancer Patients for Efficient Clinical Trial Ac-cess
Aug 9, 2022SPECTA is a quality assured platform for collecting clinicopathologically annotated biological material, imaging data, operative images, environmental assessment, questionnaires as well as patient-reported outcomes from cancer patients to support bio...
Clinical Studies - Aug 9, 2022 - Dec 31, 2027
Ongoing
Project leader: Appenzeller Christina
Members: Scherrer Julia, Quinter Janine
A PHASE 3, RANDOMIZED, MULTICENTER, OPEN-LABEL STUDY COMPARING IBERDOMIDE, DARATUMUMAB AND DEXAMETHASONE (IberDd)VERSUS DARATUMUMAB, BORTEZOMIB, AND DEXAMETHASONE (DVd) IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA (RRMM) (EXCALIBER-RRMM)
Aug 2, 2022Ziel dieser Studie ist es, die Wirksamkeit eines neuen Prüfpräparats, Iberdomid (CC-220) in Kombination mit Daratumumab und Dexamethason (IberDd) zur Behandlung des rezidivierten oder refraktären Mul-tiplen Myeloms mit der von Daratumumab, Borte-zomi...
Clinical Studies - Aug 2, 2022 - Aug 5, 2030
Ongoing
Project leader: Lehmann Thomas
Members: Aeschbacher Anette, Frehner Jan
A preliminary study validating a textile-based wearable sensor for continuous respiratory monitoring in patients during sedation
Jul 22, 2022Objective 'Proof-of-concept phase': Investigation of the accuracy and sensitivity of monitoring breathing rates of healthy study participants for specified breathing patterns Objective 'Patient monitoring phase': Investigation of accuracy and applic...
Clinical Studies - Jul 22, 2022 - Oct 31, 2023
Automatically Closed
Project leader: Filipovic Miodrag
VedolizumAb in IBD - Real-world non-Interventional, ProspEctive, ObservaTional StudY to describe real-world treatment patterns in patients on vedolizumab treatment
Jul 14, 2022This is a non-interventional prospective observational study in patients receiving Vedolizumab therapy for IBD. Sites will enroll patients with moderately to severely active IBD (UC or CD), initiating or ongoing IV induction treatment with vedolizu...
Clinical Studies - Jul 14, 2022 - Dec 31, 2023
Automatically Closed
Project leader: Brand Stephan
Members: Eckhold Annika, König Marius, Krieger-Grübel Claudia
An Open-Label, Randomized, Controlled Multi-Center Study of The Efficacy of Daromun (L19IL2 + L19TNF) Neoadjuvant Intratumoral Treatment Followed by Surgery and Adjuvant Therapy Versus Surgery and Adjuvant Therapy in Clinical Stage IIIB/C Melanoma Patients
Jul 11, 2022
Clinical Studies - Jul 11, 2022 - Dec 31, 2026
Ongoing
Project leader: Wagner Nikolaus
A Phase 1/Phase 2 Study to Evaluate the Safety and Tolerability of MK-1088 as Monotherapy and in Combination with Pembrolizumab in Participants with Advanced Solid Tumors
Jul 8, 2022Die Immuntherapie hat die Behandlung vieler Krebsraten deutlich verbessert. Tumore verfügen jedoch über mehrere Mechanismen um eine Immunantwort zu begrenzen oder der Immunüberwachung zu entgehen. Diese Studie untersucht neuartige Wege, diese Barrier...
Clinical Studies - Jul 8, 2022 - Dec 31, 2025
Ongoing
Project leader: Hess Dagmar
Members: Aeschbacher Anette, Quinter Janine
Two cohort registry study for patients with advanced CSCC treated with Cemiplimab or other approaches
Jul 1, 2022
Clinical Studies - Jul 1, 2022 - Dec 31, 2025
Ongoing
Project leader: Wagner Nikolaus
Genetic contributors of multiple myeloma cells involved in their homing and escape from T-cell recognition
Jul 1, 2022Finding highly active treatment for patients with relapsed/refractory multiple myeloma is an unmet clinical need. The immune-based treatment approaches in this population of patients have shown notable anti-myeloma activity, with deeper and durable r...
Fundamental Research - Jul 1, 2022 - Jun 30, 2023
Automatically Closed
Project leader: Besse Lenka
Members: Besse Andrej
Fibroblastendifferenzierung und -funktion im Tonsillenkarzinom
Jun 24, 2022
Fundamental Research - Jun 24, 2022 - Dec 31, 2023
Automatically Closed
Project leader: Ludewig Burkhard
Members: Meili Samuel
I6T-MC-AMAX
Jun 7, 2022A Phase 3, Multicenter, Open-Label, Long-Term Extension Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Patients with Crohn's Disease
Clinical Studies - Jun 7, 2022 - Dec 31, 2024
Ongoing
Project leader: Brand Stephan
Members: Eckhold Annika, Krieger-Grübel Claudia, König Marius
CDED Ernährungsstudie
Jun 1, 2022The Crohn’s disease exclusion diet (CDED) for induction and maintenance of remission in Crohn’s patients with or without additional medical therapy. An open label observational trial
Clinical Studies - Jun 1, 2022 - Dec 30, 2023
Automatically Closed
Project leader: Krieger-Grübel Claudia
Members: Brand Stephan, Eckhold Annika