Unit
Medizinisches Forschungszentrum
MFZ · Management
Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer.
Onder L, Papadopoulou C, Lütge A, Cheng H, Lütge M, Pérez Shibayama C, Gil Cruz C, De Martin A, Kurz L, Cadosch N, Pikor N, Rodriguez R, Born D, Jochum W, Leskow P, Dutly A, Robinson M, Ludewig B. Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer. Cell 2024
Nov 19, 2024Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer.
Nov 19, 2024Cell 2024
Onder Lucas, Papadopoulou Chrysa, Lütge Almut, Cheng Hung-Wei, Lütge Mechthild, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, De Martin Angelina, Kurz Lisa, Cadosch Nadine, Pikor Natalia, Rodriguez Regulo, Born Diana, Jochum Wolfram, Leskow Pawel, Dutly André Emanuel, Robinson Mark D, Ludewig Burkhard
STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease.
Woelfel S, Junker D, Bergamin I, Meyer-Herbon P, Stillhard R, Graf N, Leinenkugel G, Dütschler J, König M, Kammerlander L, Häuptle R, Zwyssig S, Krieger-Grübel C, Truniger S, Koller S, Metzger-Peter K, Frei N, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich W, Friedrich M, Bernsmeier C, Niess J, Korte W, Bürgi J, Dulovic A, Schneiderhan-Marra N, Semela D, Brand S. STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease. Vaccines (Basel) 2024; 12
Oct 31, 2024STAR LIGHT Study: XBB.1.5 COVID-19 mRNA Vaccines Boost Systemic but Not Mucosal Immunity Against the SARS-CoV-2 JN.1 Variant in Patients with Chronic Liver Disease.
Oct 31, 2024Vaccines (Basel) 2024; 12
Woelfel Simon, Junker Daniel, Bergamin Irina, Meyer-Herbon Pamela, Stillhard Roman, Graf Nicole, Leinenkugel Georg, Dütschler Joel, König Marius, Kammerlander Livia, Häuptle Rahel, Zwyssig Sarah, Krieger-Grübel Claudia, Truniger Samuel, Koller Seraina, Metzger-Peter Katline, Frei Nicola Fabian, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich Werner, Friedrich Matthias, Bernsmeier Christine, Niess Jan-Hendrik, Korte Wolfgang C, Bürgi Justus J, Dulovic Alex, Schneiderhan-Marra Nicole, Semela David, Brand Stephan
XBB.1.5-Adapted COVID-19 mRNA Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the SARS-CoV-2 JN.1 Variant in Patients With Inflammatory Bowel Disease.
Woelfel S, Dütschler J, Junker D, König M, Graf N, Krieger-Grübel C, Truniger S, Oikonomou V, Leinenkugel G, Koller S, Metzger-Peter K, Wyss J, Krupka N, Frei N, STAR SIGN Study Investigators, Albrich W, Friedrich M, Niess J, Schneiderhan-Marra N, Dulovic A, Misselwitz B, Korte W, Bürgi J, Brand S. XBB.1.5-Adapted COVID-19 mRNA Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the SARS-CoV-2 JN.1 Variant in Patients With Inflammatory Bowel Disease. Aliment Pharmacol Ther 2024
Oct 29, 2024XBB.1.5-Adapted COVID-19 mRNA Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the SARS-CoV-2 JN.1 Variant in Patients With Inflammatory Bowel Disease.
Oct 29, 2024Aliment Pharmacol Ther 2024
Woelfel Simon, Dütschler Joel, Junker Daniel, König Marius, Graf Nicole, Krieger-Grübel Claudia, Truniger Samuel, Oikonomou Vasileios, Leinenkugel Georg, Koller Seraina, Metzger-Peter Katline, Wyss Jacqueline, Krupka Niklas, Frei Nicola Fabian, STAR SIGN Study Investigators, Albrich Werner, Friedrich Matthias, Niess Jan-Hendrik, Schneiderhan-Marra Nicole, Dulovic Alex, Misselwitz Benjamin, Korte Wolfgang C, Bürgi Justus J, Brand Stephan
Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade.
Wyss N, Berner F, Walter V, Jochum A, Purde M, Abdou M, Sinnberg T, Hofmeister K, Pop O, Hasan A, Bauer J, Cheng H, Lütge M, Klümper N, Diem S, Kosaloglu-Yalcin Z, Zhang Y, Sellmer L, Macek B, Karbach J, König D, Läubli H, Zender L, Meyer B, Driessen C, Schürch C, Jochum W, Amaral T, Heinzerling L, Cozzio A, Hegazy A, Schneider T, Brutsche M, Sette A, Lenz T, Walz J, Rammensee H, Früh M, Jäger E, Becher B, Tufman A, Núñez N, Jörger M, Flatz L. Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade. Am J Respir Crit Care Med 2024; 210:919-930.
Oct 1, 2024Autoimmunity Against Surfactant Protein B Is Associated with Pneumonitis During Checkpoint Blockade.
Oct 1, 2024Am J Respir Crit Care Med 2024; 210:919-930
Wyss Nina, Berner Fiamma, Walter Vincent, Jochum Ann-Kristin, Purde Mette T, Abdou Marie-Therese, Sinnberg Tobias, Hofmeister Kathrin, Pop Oltin, Hasan Ali, Bauer Jens, Cheng Hung-Wei, Lütge Mechthild, Klümper Niklas, Diem Stefan, Kosaloglu-Yalcin Zeynep, Zhang Yizheng, Sellmer Laura, Macek Boris, Karbach Julia, König David, Läubli Heinz, Zender Lars, Meyer Britta S, Driessen Christoph, Schürch Christian M, Jochum Wolfram, Amaral Teresa, Heinzerling Lucie M, Cozzio Antonio, Hegazy AhN, Schneider Tino, Brutsche Martin, Sette Alessandro, Lenz Tobias L, Walz Juliane Sarah, Rammensee Hans-Georg, Früh Martin, Jäger Elke, Becher Burkhard, Tufman Amanda, Núñez Nicolás Gonzalo, Jörger Markus, Flatz Lukas
Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity.
Bessell E, Finlay R, James L, Ludewig B, Harris N, Krebs P, Hepworth M, Dubey L. Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity. Cell Rep 2024; 43:114620.
Aug 13, 2024Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity.
Aug 13, 2024Cell Rep 2024; 43:114620
Bessell Emily, Finlay Rachel E, James Louisa K, Ludewig Burkhard, Harris Nicola L, Krebs Philippe, Hepworth Matthew R, Dubey Lalit Kumar
Systemic and Mucosal Immunogenicity of Monovalent XBB.1.5-Adapted COVID-19 mRNA Vaccines in Patients with Inflammatory Bowel Disease.
Woelfel S, Dütschler J, Junker D, König M, Leinenkugel G, Graf N, Krieger-Grübel C, Truniger S, Franke A, Koller S, Metzger-Peter K, Oberholzer M, Frei N, Geissler N, Schaub P, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich W, Friedrich M, Niess J, Schneiderhan-Marra N, Dulovic A, Korte W, Bürgi J, Brand S. Systemic and Mucosal Immunogenicity of Monovalent XBB.1.5-Adapted COVID-19 mRNA Vaccines in Patients with Inflammatory Bowel Disease. Vaccines (Basel) 2024; 12
Jul 15, 2024Systemic and Mucosal Immunogenicity of Monovalent XBB.1.5-Adapted COVID-19 mRNA Vaccines in Patients with Inflammatory Bowel Disease.
Jul 15, 2024Vaccines (Basel) 2024; 12
Woelfel Simon, Dütschler Joel, Junker Daniel, König Marius, Leinenkugel Georg, Graf Nicole, Krieger-Grübel Claudia, Truniger Samuel, Franke Annett, Koller Seraina, Metzger-Peter Katline, Oberholzer Melanie, Frei Nicola Fabian, Geissler Nora, Schaub Peter, Genetics And Observational Subarachnoid Haemorrhage Gosh Study Investigators, Albrich Werner, Friedrich Matthias, Niess Jan-Hendrik, Schneiderhan-Marra Nicole, Dulovic Alex, Korte Wolfgang C, Bürgi Justus J, Brand Stephan
Sustained innate interferon is an essential inducer of tertiary lymphoid structures.
Calvanese A, Cecconi V, Stäheli S, Schnepf D, Nater M, Pereira P, Gschwend J, Heikenwalder M, Schneider C, Ludewig B, Silina K, van den Broek M. Sustained innate interferon is an essential inducer of tertiary lymphoid structures. Eur J Immunol 2024; 54:e2451207.
Jul 9, 2024Sustained innate interferon is an essential inducer of tertiary lymphoid structures.
Jul 9, 2024Eur J Immunol 2024; 54:e2451207
Calvanese Anna Laura, Cecconi Virginia, Stäheli Severin, Schnepf Daniel, Nater Marc, Pereira Paulo, Gschwend Julia, Heikenwalder Mathias, Schneider Christoph, Ludewig Burkhard, Silina Karina, van den Broek Maries
Temporal evolution of primary angiitis of the central nervous system (PACNS) on MRI following immunosuppressant treatment.
Wagner F, Almeida G, Willems E, Weber J, Geiss J, Hundsberger T, Mordasini P, Wildermuth S, Leschka S, Wälti S, Dietrich T, Fischer T. Temporal evolution of primary angiitis of the central nervous system (PACNS) on MRI following immunosuppressant treatment. Insights Imaging 2024; 15:140.
Jun 9, 2024Temporal evolution of primary angiitis of the central nervous system (PACNS) on MRI following immunosuppressant treatment.
Jun 9, 2024Insights Imaging 2024; 15:140
Wagner Franca, Almeida Gonçalo G, Willems Erik, Weber Johannes, Geiss Johannes, Hundsberger Thomas, Mordasini Pasquale, Wildermuth Simon, Leschka Sebastian, Wälti Stephan, Dietrich Tobias Johannes, Fischer Tim Steffen
Cardiac Fibroblastic Niches in Homeostasis and Inflammation.
Cadosch N, Gil Cruz C, Pérez Shibayama C, Ludewig B. Cardiac Fibroblastic Niches in Homeostasis and Inflammation. Circ Res 2024; 134:1703-1717.
Jun 6, 2024Cardiac Fibroblastic Niches in Homeostasis and Inflammation.
Jun 6, 2024Circ Res 2024; 134:1703-1717
Cadosch Nadine, Gil Cruz Cristina, Pérez Shibayama Christian Ivan, Ludewig Burkhard
Bone morphogenic protein-4 availability in the cardiac microenviroment controls inflammation and fibrosis in autoimmune myocarditis
Pérez Shibayama C, Gil Cruz C, Cadosch N, Lütge M, Cheng H, De Martin A, Frischmann K, Joachimbauer A, Onder L, Papadopoulou I, Papadopoulou C, Ring S, Krebs P, P. Vu V, P. Nägele M, Rosi V, Parianos D, Zsilavecz V, Cooper L, Flammer A, Ruschitzka F, Reiner P, Schmidt D, Ludewig B. Bone morphogenic protein-4 availability in the cardiac microenviroment controls inflammation and fibrosis in autoimmune myocarditis. Nature Cardiovascular Research 2024; volume 3:301-316.
Apr 19, 2024Bone morphogenic protein-4 availability in the cardiac microenviroment controls inflammation and fibrosis in autoimmune myocarditis
Apr 19, 2024Nature Cardiovascular Research 2024; volume 3:301-316
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Cadosch Nadine, Lütge Mechthild, Cheng Hung-Wei, De Martin Angelina, Frischmann Kira, Joachimbauer Anna, Onder Lucas, Papadopoulou Iliana, Papadopoulou Chrysa, Ring Sandra, Krebs Philippe, P. Vu Vivian, P. Nägele Matthias, Rosi Valentina, Parianos Danae, Zsilavecz Valentin W, Cooper Leslie T., Flammer Andreas, Ruschitzka Frank, Reiner Peter P, Schmidt Dörthe, Ludewig Burkhard
Bone morphogenic protein-4 availability in the cardiac microenvironment controls inflammation and fibrosis in autoimmune myocarditis.
Pérez Shibayama C, Gil Cruz C, Cadosch N, Lütge M, Cheng H, De Martin A, Frischmann K, Joachimbauer A, Onder L, Papadopoulou I, Papadopoulou C, Ring S, Krebs P, P. Vu V, P. Nägele M, Rossi V, Parianos D, Zsilavecz V, Cooper L, Flammer A, Ruschitzka F, Rainer P, Schmidt D, Ludewig B. Bone morphogenic protein-4 availability in the cardiac microenvironment controls inflammation and fibrosis in autoimmune myocarditis. Nat Cardiovasc Res 2024; 3:301-316.
Feb 19, 2024Bone morphogenic protein-4 availability in the cardiac microenvironment controls inflammation and fibrosis in autoimmune myocarditis.
Feb 19, 2024Nat Cardiovasc Res 2024; 3:301-316
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Cadosch Nadine, Lütge Mechthild, Cheng Hung-Wei, De Martin Angelina, Frischmann Kira, Joachimbauer Anna, Onder Lucas, Papadopoulou Iliana, Papadopoulou Chrysa, Ring Sandra Stephanie, Krebs Philippe, P. Vu Vivian, P. Nägele Matthias, Rossi Valentina A, Parianos Danae, Zsilavecz Valentin W, Cooper Leslie T., Flammer Andreas J, Ruschitzka Frank, Rainer Peter P, Schmidt Dörthe, Ludewig Burkhard
Diagnostic performance of long head of biceps tendon tears on MRI: systematic review and meta-analysis.
Almeida G, Graf N, Wildermuth S, Fischer T, Wälti S, Jacxsens M, Leschka S, Dietrich T. Diagnostic performance of long head of biceps tendon tears on MRI: systematic review and meta-analysis. Eur Radiol 2023
Dec 27, 2023Diagnostic performance of long head of biceps tendon tears on MRI: systematic review and meta-analysis.
Dec 27, 2023Eur Radiol 2023
Almeida Gonçalo G, Graf Nicole, Wildermuth Simon, Fischer Tim, Wälti Stephan, Jacxsens Matthijs, Leschka Sebastian, Dietrich Tobias
A replicating LCMV-based vaccine for the treatment of solid tumors.
Purde M, Cupovic J, Palmowski Y, Makky A, Schmidt S, Rochwarger A, Hartmann F, Stemeseder F, Lercher A, Abdou M, Bomze D, Besse L, Berner F, Tüting T, Hölzel M, Bergthaler A, Kochanek S, Ludewig B, Lauterbach H, Orlinger K, Bald T, Schietinger A, Schürch C, Ring S, Flatz L. A replicating LCMV-based vaccine for the treatment of solid tumors. Mol Ther 2023
Dec 5, 2023A replicating LCMV-based vaccine for the treatment of solid tumors.
Dec 5, 2023Mol Ther 2023
Purde Mette-Triin, Cupovic Jovana, Palmowski Yannick A, Makky Ahmad, Schmidt Sarah, Rochwarger Alexander, Hartmann Fabienne, Stemeseder Felix, Lercher Alexander, Abdou Marie-Therese, Bomze David, Besse Lenka, Berner Fiamma, Tüting Thomas, Hölzel Michael, Bergthaler Andreas, Kochanek Stefan, Ludewig Burkhard, Lauterbach Henning, Orlinger Klaus K, Bald Tobias, Schietinger Andrea, Schürch Christian M, Ring Sandra Stephanie, Flatz Lukas
Protective fibroblastic niches in secondary lymphoid organs.
De Martin A, Stanossek Y, Pikor N, Ludewig B. Protective fibroblastic niches in secondary lymphoid organs. J Exp Med 2023; 221
Dec 1, 2023Protective fibroblastic niches in secondary lymphoid organs.
Dec 1, 2023J Exp Med 2023; 221
De Martin Angelina, Stanossek Yves, Pikor Natalia Barbara, Ludewig Burkhard
Author Correction: Long-term retention of antigens in germinal centers is controlled by the spatial organization of the follicular dendritic cell network.
Martínez-Riaño A, Wang S, Boeing S, Minoughan S, Casal A, Spillane K, Ludewig B, Tolar P. Author Correction: Long-term retention of antigens in germinal centers is controlled by the spatial organization of the follicular dendritic cell network. Nat Immunol 2023
Oct 20, 2023Author Correction: Long-term retention of antigens in germinal centers is controlled by the spatial organization of the follicular dendritic cell network.
Oct 20, 2023Nat Immunol 2023
Martínez-Riaño Ana, Wang Shenshen, Boeing Stefan, Minoughan Sophie, Casal Antonio, Spillane Katelyn M, Ludewig Burkhard, Tolar Pavel
Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
Lichtensteiger C, Koblischke M, Berner F, Jochum A, Sinnberg T, Balciunaite B, Purde M, Walter V, Abdou M, Hofmeister K, Kohler P, Vernazza P, Albrich W, Kahlert C, Zoufaly A, Traugott M, Kern L, Pietsch U, Kleger G, Filipovic M, Kneilling M, Cozzio A, Pop O, Bomze D, Bergthaler A, Hasan A, Aberle J, Flatz L. Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients. J Autoimmun 2023; 140:103118.
Oct 10, 2023Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients.
Oct 10, 2023J Autoimmun 2023; 140:103118
Lichtensteiger Christa, Koblischke Maximilian, Berner Fiamma, Jochum Ann-Kristin, Sinnberg Tobias, Balciunaite Beatrice, Purde Mette-Triin, Walter Vincent, Abdou Marie-Therese, Hofmeister Kathrin, Kohler Philipp, Vernazza Pietro L, Albrich Werner, Kahlert Christian, Zoufaly Alexander, Traugott Marianna T, Kern Lukas, Pietsch Urs, Kleger Gian-Reto, Filipovic Miodrag, Kneilling Manfred, Cozzio Antonio, Pop Oltin, Bomze David, Bergthaler Andreas, Hasan Ali, Aberle Judith, Flatz Lukas
Electrical impedance spectroscopy detects skin barrier dysfunction in childhood atopic dermatitis.
Sasaki M, Sundberg M, Frei R, Ferstl R, Heye K, Willems E, Akdis C, Lauener R, CK-CARE Study Group, Roduit C. Electrical impedance spectroscopy detects skin barrier dysfunction in childhood atopic dermatitis. Allergy 2023; 79:142-152.
Sep 27, 2023Electrical impedance spectroscopy detects skin barrier dysfunction in childhood atopic dermatitis.
Sep 27, 2023Allergy 2023; 79:142-152
Sasaki Mari, Sundberg Mathilda, Frei Remo, Ferstl Ruth, Heye Kristina N, Willems Erik, Akdis Cezmi A, Lauener Roger, CK-CARE Study Group, Roduit Caroline
The slowing of peripheral nerve conduction velocity in children and adolescents with type 1 diabetes is predicted by glucose fluctuations.
Oberhauser S, l'Allemand-Jander D, Willems E, Gozzi T, Heldt K, Eilers M, Stasinaki A, Lütschg J, Broser P. The slowing of peripheral nerve conduction velocity in children and adolescents with type 1 diabetes is predicted by glucose fluctuations. Diabetes 2023
Sep 12, 2023The slowing of peripheral nerve conduction velocity in children and adolescents with type 1 diabetes is predicted by glucose fluctuations.
Sep 12, 2023Diabetes 2023
Oberhauser Sarah S, l'Allemand-Jander Dagmar, Willems Erik, Gozzi Tiziana, Heldt Katrin, Eilers Miriam, Stasinaki Aikaterini, Lütschg Jürg, Broser Philip Julian
Prospective evaluation of ultrasound features of magnesium-based bioabsorbable screw resorption in pediatric fractures.
Wälti S, Fandak J, Markart S, Willems E, Wildermuth S, Fischer T, Dietrich T, Matissek C, Krebs T. Prospective evaluation of ultrasound features of magnesium-based bioabsorbable screw resorption in pediatric fractures. Eur Radiol 2023
Sep 2, 2023Prospective evaluation of ultrasound features of magnesium-based bioabsorbable screw resorption in pediatric fractures.
Sep 2, 2023Eur Radiol 2023
Wälti Stephan, Fandak Jozef, Markart Stefan, Willems Erik, Wildermuth Simon, Fischer Tim, Dietrich Tobias, Matissek Christoph, Krebs Thomas
STAR SIGN study: Evaluation of COVID-19 vaccine efficacy against the SARS-CoV-2 variants BQ.1.1 and XBB.1.5 in patients with inflammatory bowel disease.
Woelfel S, Dütschler J, König M, Dulovic A, Graf N, Junker D, Oikonomou V, Krieger-Grübel C, Truniger S, Franke A, Eckhold A, Forsch K, Koller S, Wyss J, Krupka N, Oberholzer M, Frei N, Geissler N, Schaub P, STAR SIGN Study Investigators, Albrich W, Friedrich M, Schneiderhan-Marra N, Misselwitz B, Korte W, Bürgi J, Brand S. STAR SIGN study: Evaluation of COVID-19 vaccine efficacy against the SARS-CoV-2 variants BQ.1.1 and XBB.1.5 in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2023; 58:678-691.
Aug 12, 2023STAR SIGN study: Evaluation of COVID-19 vaccine efficacy against the SARS-CoV-2 variants BQ.1.1 and XBB.1.5 in patients with inflammatory bowel disease.
Aug 12, 2023Aliment Pharmacol Ther 2023; 58:678-691
Woelfel Simon, Dütschler Joel, König Marius, Dulovic Alex, Graf Nicole, Junker Daniel, Oikonomou Vasileios, Krieger-Grübel Claudia, Truniger Samuel, Franke Annett, Eckhold Annika, Forsch Kristina, Koller Seraina, Wyss Jacqueline, Krupka Niklas, Oberholzer Melanie, Frei Nicola Fabian, Geissler Nora, Schaub Peter, STAR SIGN Study Investigators, Albrich Werner, Friedrich Matthias, Schneiderhan-Marra Nicole, Misselwitz Benjamin, Korte Wolfgang C, Bürgi Justus J, Brand Stephan