Bereich
Medizinisches Forschungszentrum
MFZ · Dept. Direktion
Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells
Cupovic J, Klenerman P, Engeler D, Krebs P, Scandella E, Oxenius A, Flatz L, Provine N, De Martin A, Cheng H, Lütge M, Colston J, Onder L, Ring S, Ludewig B. Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells. Nat Immunol 2021; 22:1042-1051.
15.07.2021Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells
15.07.2021Nat Immunol 2021; 22:1042-1051
Cupovic Jovana, Klenerman Paul, Engeler Daniel, Krebs Philippe, Scandella Elke, Oxenius Annette, Flatz Lukas, Provine Nicholas M, De Martin Angelina, Cheng Hung-Wei, Lütge Mechthild, Colston Julia M, Onder Lucas, Ring Sandra, Ludewig Burkhard
Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis
Rubbert-Roth A, Vuilleumier N, Ludewig B, Schmiedeberg K, Haller C, von Kempis J. Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis. Lancet Rheumatol 2021; 3:e470-e472.
08.06.2021Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis
08.06.2021Lancet Rheumatol 2021; 3:e470-e472
Rubbert-Roth Andrea, Vuilleumier Nicolas, Ludewig Burkhard, Schmiedeberg Kristin, Haller Christoph, von Kempis Johannes
Fractional CO laser to improve noticeable scars after skin cancer surgery: An appraisal by the patients, laypersons, and experts.
Wyss N, Graf N, Hafner J, Imhof L. Fractional CO laser to improve noticeable scars after skin cancer surgery: An appraisal by the patients, laypersons, and experts. Dermatol Ther 2021; 34:e14999.
31.05.2021Fractional CO laser to improve noticeable scars after skin cancer surgery: An appraisal by the patients, laypersons, and experts.
31.05.2021Dermatol Ther 2021; 34:e14999
Wyss Nina, Graf Nicole, Hafner Jürg, Imhof Laurence
Differentiation and activation of fibroblastic reticular cells
Lütge M, Pikor N, Ludewig B. Differentiation and activation of fibroblastic reticular cells. Immunol Rev 2021; 302:32-46.
27.05.2021Differentiation and activation of fibroblastic reticular cells
27.05.2021Immunol Rev 2021; 302:32-46
Lütge Mechthild, Pikor Natalia, Ludewig Burkhard
Fibroblasts as immune regulators in infection, inflammation and cancer
Davidson S, Coles M, Thomas T, Kollias G, Ludewig B, Turley S, Brenner M, Buckley C. Fibroblasts as immune regulators in infection, inflammation and cancer. Nat Rev Immunol 2021; 21:704-717.
28.04.2021Fibroblasts as immune regulators in infection, inflammation and cancer
28.04.2021Nat Rev Immunol 2021; 21:704-717
Davidson Sarah, Coles Mark, Thomas Tom, Kollias George, Ludewig Burkhard, Turley Shannon, Brenner Michael, Buckley Christopher D
Insights into coronavirus immunity taught by the murine coronavirus
Grabherr S, Ludewig B, Pikor N. Insights into coronavirus immunity taught by the murine coronavirus. Eur J Immunol 2021; 51:1062-1070.
22.03.2021Insights into coronavirus immunity taught by the murine coronavirus
22.03.2021Eur J Immunol 2021; 51:1062-1070
Grabherr Sarah, Ludewig Burkhard, Pikor Natalia
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity
Prados A, Ludewig B, Koliaraki V, Pérez Shibayama C, Gil Cruz C, Lütge M, Mörbe U, Cheng H, Onder L, Kollias G. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol 2021; 22:510-519.
11.03.2021Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity
11.03.2021Nat Immunol 2021; 22:510-519
Prados Alejandro, Ludewig Burkhard, Koliaraki Vasiliki, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Lütge Mechthild, Mörbe Urs, Cheng Hung-Wei, Onder Lucas, Kollias George
The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis
Seidenberg J, Stellato M, Hukara A, Ludewig B, Klingel K, Distler O, Błyszczuk P, Kania G. The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis. Int J Mol Sci 2021; 22
13.02.2021The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis
13.02.2021Int J Mol Sci 2021; 22
Seidenberg Jemima, Stellato Mara, Hukara Amela, Ludewig Burkhard, Klingel Karin, Distler Oliver, Błyszczuk Przemysław, Kania Gabriela
Recombinant lymphocytic choriomeningitis virus-based vaccine vector protects type I interferon receptor deficient mice from viral challenge
Królik M, Csepregi L, Hartmann F, Engetschwiler C, Flatz L. Recombinant lymphocytic choriomeningitis virus-based vaccine vector protects type I interferon receptor deficient mice from viral challenge. Vaccine 2021; 39:1257-1264.
29.01.2021Recombinant lymphocytic choriomeningitis virus-based vaccine vector protects type I interferon receptor deficient mice from viral challenge
29.01.2021Vaccine 2021; 39:1257-1264
Królik Michał Wojciech, Csepregi Lucia, Hartmann Fabienne, Engetschwiler Céline, Flatz Lukas
Development and Immunological Function of Lymph Node Stromal Cells
Pikor N, Cheng H, Onder L, Ludewig B. Development and Immunological Function of Lymph Node Stromal Cells. J Immunol 2021; 206:257-263.
15.01.2021Development and Immunological Function of Lymph Node Stromal Cells
15.01.2021J Immunol 2021; 206:257-263
Pikor Natalia, Cheng Hung-Wei, Onder Lucas, Ludewig Burkhard
PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages
Okreglicka K, Schneider C, Nielsen P, Ludewig B, Kurrer M, Feng Q, Onder L, Pohlmeier L, Iten I, Kopf M. PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages. J Exp Med 2021; 218
03.01.2021PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages
03.01.2021J Exp Med 2021; 218
Okreglicka Katarzyna, Schneider Christoph, Nielsen Peter, Ludewig Burkhard, Kurrer Michael, Feng Qian, Onder Lucas, Pohlmeier Lea, Iten Irina, Kopf Manfred
Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies
Hasan Ali O, Penninger J, Bergthaler A, Popa A, Gómez-Mejia A, Schüpbach R, Bühler P, Vernazza P, Kahlert C, Kohler P, Albrich W, Kern L, Thiel S, Weber M, Paprotny M, Brugger S, Risch L, Bomze D, Flatz L. Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies. Clin Infect Dis 2021; 73:e2869-e2874.
02.01.2021Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies
02.01.2021Clin Infect Dis 2021; 73:e2869-e2874
Hasan Ali Omar, Penninger Josef M, Bergthaler Andreas, Popa Alexandra M, Gómez-Mejia Alejandro, Schüpbach Reto A, Bühler Philipp K, Vernazza Pietro, Kahlert Christian, Kohler Philipp, Albrich Werner, Kern Lukas, Thiel Sarah, Weber Myriam, Paprotny Matthias, Brugger Silvio D, Risch Lorenz, Bomze David, Flatz Lukas
Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues
Guendel F, Hehlgans T, Waisman A, Becher B, Giannou A, Brachs S, Ebert K, Tanriver Y, Ludewig B, Mashreghi M, Kruglov A, Pfeffer K, Herold S, Ruedl C, Kofoed-Branzk M, Gronke K, Tizian C, Witkowski M, Cheng H, Heinz G, Heinrich F, Durek P, Norris P, Ware C, Diefenbach A. Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues. Immunity 2020; 53:1015-1032.e8.
17.11.2020Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues
17.11.2020Immunity 2020; 53:1015-1032.e8
Guendel Fabian, Hehlgans Thomas, Waisman Ari, Becher Burkhard, Giannou Anastasios D, Brachs Sebastian, Ebert Karolina, Tanriver Yakup, Ludewig Burkhard, Mashreghi Mir-Farzin, Kruglov Andrey A, Pfeffer Klaus, Herold Susanne, Ruedl Christiane, Kofoed-Branzk Michael, Gronke Konrad, Tizian Caroline, Witkowski Mario, Cheng Hung-Wei, Heinz Gitta Anne, Heinrich Frederik, Durek Pawel, Norris Paula S, Ware Carl F, Diefenbach Andreas
Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity
Bocharov G, Casella V, Argilaguet J, Grebennikov D, Güerri-Fernandez R, Ludewig B, Meyerhans A. Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity. Front Cell Infect Microbiol 2020; 10:559209.
23.10.2020Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity
23.10.2020Front Cell Infect Microbiol 2020; 10:559209
Bocharov Gennady, Casella Valentina, Argilaguet Jordi, Grebennikov Dmitry, Güerri-Fernandez Roberto, Ludewig Burkhard, Meyerhans Andreas
Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8 T Cell Responses
Ring S, Królik M, Hartmann F, Schmidt E, Ali O, Ludewig B, Kochanek S, Flatz L. Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8 T Cell Responses. Mol Ther Oncolytics 2020; 19:179-187.
10.10.2020Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8 T Cell Responses
10.10.2020Mol Ther Oncolytics 2020; 19:179-187
Ring Sandra, Królik Michał Wojciech, Hartmann Fabienne, Schmidt Erika, Ali Omar Hasan, Ludewig Burkhard, Kochanek Stefan, Flatz Lukas
Survival-Inferred Fragility Index of Phase 3 Clinical Trials Evaluating Immune Checkpoint Inhibitors
Bomze D, Asher N, Hasan A, Flatz L, Azoulay D, Markel G, Meirson T. Survival-Inferred Fragility Index of Phase 3 Clinical Trials Evaluating Immune Checkpoint Inhibitors. JAMA Netw Open 2020; 3:e2017675.
01.10.2020Survival-Inferred Fragility Index of Phase 3 Clinical Trials Evaluating Immune Checkpoint Inhibitors
01.10.2020JAMA Netw Open 2020; 3:e2017675
Bomze David, Asher Nethanel, Hasan Ali, Flatz Lukas, Azoulay Daniel, Markel Gal, Meirson Tomer
Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
Pérez Shibayama C, Gil Cruz C, Colston J, Novkovic M, De Martin A, Ring S, Onder L, Cheng H, Lütge M, Islander U, Ludewig B. Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells. Sci Immunol 2020; 5
11.09.2020Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
11.09.2020Sci Immunol 2020; 5
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Colston Julia, Novkovic Mario, De Martin Angelina, Ring Sandra, Onder Lucas, Cheng Hung-Wei, Lütge Mechthild, Islander Ulrika, Ludewig Burkhard
Fingolimod and tumor-infiltrating lymphocytes in checkpoint-inhibitor treated cancer patients
Hasan Ali O, Hundsberger T, Diem S, Müller S, Pop O, Markert E, Müller J, Moulin A, Ring S, Ackermann C, Berner F, Flatz L. Fingolimod and tumor-infiltrating lymphocytes in checkpoint-inhibitor treated cancer patients. Cancer Immunol Immunother 2020; 70:563-568.
17.08.2020Fingolimod and tumor-infiltrating lymphocytes in checkpoint-inhibitor treated cancer patients
17.08.2020Cancer Immunol Immunother 2020; 70:563-568
Hasan Ali Omar, Hundsberger Thomas, Diem Stefan, Müller Stefanie, Pop Oltin, Markert Eva, Müller Joachim, Moulin Alexandre, Ring Sandra, Ackermann Christoph Jakob, Berner Fiamma, Flatz Lukas
Ocular Adverse Events Induced by Immune Checkpoint Inhibitors: A Comprehensive Pharmacovigilance Analysis
Bomze D, Meirson T, Hasan A, Goldman A, Flatz L, Habot-Wilner Z. Ocular Adverse Events Induced by Immune Checkpoint Inhibitors: A Comprehensive Pharmacovigilance Analysis. Ocul Immunol Inflamm 2020:1-7.
04.08.2020Ocular Adverse Events Induced by Immune Checkpoint Inhibitors: A Comprehensive Pharmacovigilance Analysis
04.08.2020Ocul Immunol Inflamm 2020:1-7
Bomze David, Meirson Tomer, Hasan Ali, Goldman Adam, Flatz Lukas, Habot-Wilner Zohar
B cell zone reticular cell microenvironments shape CXCL13 gradient formation
Cosgrove J, Uguccioni M, Legler D, Lacey C, Coatesworth A, Polak W, Cupedo T, Manoury B, Thelen M, Stein J, Wolf M, Leake M, Timmis J, Ludewig B, Heller M, Venetz D, Taylor E, Novkovic M, Albrecht S, Pikor N, Zhou Z, Onder L, Mörbe U, Cupovic J, Miller H, Alden K, Thuery A, O'Toole P, Pinter R, Jarrett S, Coles M. B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nat Commun 2020; 11:3677.
22.07.2020B cell zone reticular cell microenvironments shape CXCL13 gradient formation
22.07.2020Nat Commun 2020; 11:3677
Cosgrove Jason, Uguccioni Mariagrazia, Legler Daniel F, Lacey Charles J, Coatesworth Andrew, Polak Wojciech G, Cupedo Tom, Manoury Bénedicte, Thelen Marcus, Stein Jens V, Wolf Marlene, Leake Mark C, Timmis Jon, Ludewig Burkhard, Heller Manfred, Venetz Daniel, Taylor Emily, Novkovic Mario, Albrecht Stefan, Pikor Natalia, Zhou Zhaoukun, Onder Lucas, Mörbe Urs, Cupovic Jovana, Miller Helen, Alden Kieran, Thuery Anne, O'Toole Peter, Pinter Rita, Jarrett Simon, Coles Mark C