Publikation

The History of Target-Controlled Infusion

Wissenschaftlicher Artikel/Review - 01.01.2016

Bereiche
PubMed
DOI

Zitation
Struys M, De Smet T, Glen J, Vereecke H, Absalom A, Schnider T. The History of Target-Controlled Infusion. Anesth Analg 2016; 122:56-69.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Anesth Analg 2016; 122
Veröffentlichungsdatum
01.01.2016
eISSN (Online)
1526-7598
Seiten
56-69
Kurzbeschreibung/Zielsetzung

Target-controlled infusion (TCI) is a technique of infusing IV drugs to achieve a user-defined predicted ("target") drug concentration in a specific body compartment or tissue of interest. In this review, we describe the pharmacokinetic principles of TCI, the development of TCI systems, and technical and regulatory issues addressed in prototype development. We also describe the launch of the current clinically available systems.