Publikation

Biochemical Recurrence in Prostate Cancer: The European Association of Urology Prostate Cancer Guidelines Panel Recommendations

Wissenschaftlicher Artikel/Review - 24.06.2019

Bereiche
PubMed
DOI

Zitation
Van den Broeck T, Liew M, Mason M, Moris L, Schoots I, van der Kwast T, van der Poel H, Wiegel T, Willemse P, Rouvière O, Lam T, Lardas M, Henry A, van den Bergh R, Briers E, Cornford P, Cumberbatch M, Tilki D, De Santis M, Fanti S, Fossati N, Gillessen Sommer S, Grummet J, Mottet N. Biochemical Recurrence in Prostate Cancer: The European Association of Urology Prostate Cancer Guidelines Panel Recommendations. Eur Urol Focus 2019
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Eur Urol Focus 2019
Veröffentlichungsdatum
24.06.2019
eISSN (Online)
2405-4569
Kurzbeschreibung/Zielsetzung

Biochemical recurrence (BCR) after primary treatment of localized prostate cancer does not necessarily lead to clinically apparent progressive disease. To aid in prognostication, the European Association of Urology prostate cancer guidelines panel undertook a systematic review and successfully developed a novel BCR risk stratification system (groups with a low risk or high risk of BCR) based on disease and prostate-specific antigen characteristics. PATIENT SUMMARY: Following treatment to cure prostate cancer, some patients can develop recurrence of disease identified via a prostate-specific antigen blood test (ie, biochemical recurrence, or BCR). However, not every man who experiences BCR develops progressive disease (symptoms or evidence of disease progression on imaging). We conducted a review of the literature and developed a classification system for predicting which patients might progress to optimize treatment decisions.