The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts
Wissenschaftlicher Artikel/Review - 27.12.2019
Putora Paul Martin, Belderbos Jose, Dziadziuszko Rafal, Le Pechoux Cecile, McDonald Fiona, Nestle Ursula, Peeters Stephanie, Pöttgen Christoph, Ramella Sara, Slotman Ben J, Troost Esther G C, Van Houtte Paul, Widder Joachim, Glatzer Markus, De Ruysscher Dirk, Faivre-Finn Corinne
The role of prophylactic cranial irradiation (PCI) and thoracic radiotherapy (TRT) is unclear in resected small cell lung cancer (SCLC).
Thirteen European radiotherapy experts on SCLC were asked to describe their strategies on PCI and TRT for patients with resected SCLC. The treatment strategies were converted into decision trees and analyzed for consensus and discrepancies.
For patients with resected SCLC and positive lymph nodes most experts recommend prophylactic cranial irradiation and thoracic radiotherapy. For elderly patients with resected node negative SCLC, most experts do not recommend thoracic radiotherapy or prophylactic cranial irradiation.
PCI and TRT are considered in patients with resected SCLC and these treatments should be discussed with the patient in the context of shared decision-making.