Factors to Consider When Assessing the Diagnostic Accuracy of Synovial Leukocyte Count in Periprosthetic Joint Infection

Publikation

Factors to Consider When Assessing the Diagnostic Accuracy of Synovial Leukocyte Count in Periprosthetic Joint Infection

Wissenschaftlicher Artikel/Review - 02.08.2019

Ottink Karsten D, Strahm Carol, Muller-Kobold Anneke, Sendi Parham, Wouthuyzen-Bakker Marjan

Zitation

Ottink K, Strahm C, Muller-Kobold A, Sendi P, Wouthuyzen-Bakker M. Factors to Consider When Assessing the Diagnostic Accuracy of Synovial Leukocyte Count in Periprosthetic Joint Infection. J Bone Jt Infect 2019; 4:167-173.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

J Bone Jt Infect 2019; 4

Veröffentlichungsdatum

02.08.2019

ISSN (Druck)

2206-3552

Seiten

167-173

Kurzbeschreibung/Zielsetzung

Synovial white blood cell (WBC) count and the percentage of polymorphonuclear leucocytes (PMN%) is one of the diagnostic criteria to diagnose a periprosthetic joint infection (PJI). Although the test is widely available, the diagnostic accuracy of proposed cut-off levels are influenced by several factors, such as: the affected joint, co-morbid conditions, the causative microorganism and the gathering and processing of samples in the laboratory. In this narrative review we provide an overview on how and to what extent these factors can affect the synovial WBC count and PMN% in synovial fluid.