Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07).

Publikation

Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07).

Wissenschaftlicher Artikel/Review - 19.02.2018

Beier Dagmar, Proescholdt Martin, Reinert Christiane, Pietsch Torsten, Jones David T W, Pfister Stefan M, Hattingen Elke, Seidel Clemens, Dirven Linda, Luerding Ralf, Reijneveld Jaap, Warmuth-Metz Monika, Bonsanto Matteo, Bremer Michael, Combs Stephanie E, Rieken Stefan, Herrlinger Ulrich, Kuntze Holger, Mayer-Steinacker Regine, Moskopp Dag, Schneider Thomas, Beringer Andreas, Schlegel Uwe, Stummer Walter, Welker Helmut, Weyerbrock Astrid, Paulsen Frank, Rutkowski Stefan, Weller Michael, Wick Wolfgang, Kortmann Rolf-Dieter, Bogdahn Ulrich, Hau Peter

Zitation

Beier D, Proescholdt M, Reinert C, Pietsch T, Jones D, Pfister S, Hattingen E, Seidel C, Dirven L, Luerding R, Reijneveld J, Warmuth-Metz M, Bonsanto M, Bremer M, Combs S, Rieken S, Herrlinger U, Kuntze H, Mayer-Steinacker R, Moskopp D, Schneider T, Beringer A, Schlegel U, Stummer W, Welker H, Weyerbrock A, Paulsen F, Rutkowski S, Weller M, Wick W, Kortmann R, Bogdahn U, Hau P. Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07). Neuro Oncol 2018; 20:400-410.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Neuro Oncol 2018; 20

Veröffentlichungsdatum

19.02.2018

eISSN (Online)

1523-5866

Seiten

400-410

Kurzbeschreibung/Zielsetzung

Medulloblastoma in adult patients is rare, with 0.6 cases per million. Prognosis depends on clinical factors and medulloblastoma entity. No prospective data on the feasibility of radiochemotherapy exist. The German Neuro-Oncology Working Group (NOA) performed a prospective descriptive multicenter single-arm phase II trial to evaluate feasibility and toxicity of radio-polychemotherapy.