Helicobacter pylori detected in pharyngeal and laryngeal pathologies in patients with proven gastric colonization

Publikation

Helicobacter pylori detected in pharyngeal and laryngeal pathologies in patients with proven gastric colonization

Wissenschaftlicher Artikel/Review - 12.12.2013

Fellmann Jonas, Weisert Jan U, Soltermann Alex, Morand Grégoire, Morra Laura, Moch Holger, Huber Gerhard, Probst Rudolf

Zitation

Fellmann J, Weisert J, Soltermann A, Morand G, Morra L, Moch H, Huber G, Probst R. Helicobacter pylori detected in pharyngeal and laryngeal pathologies in patients with proven gastric colonization. Head & neck 2013; 36:1562-6.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Head & neck 2013; 36

Veröffentlichungsdatum

12.12.2013

eISSN (Online)

1097-0347

Seiten

1562-6

Kurzbeschreibung/Zielsetzung

BACKGROUND
Helicobacter pylori is known to cause gastric cancer. Presence and carcinogenicity in the upper aerodigestive system is doubtful. This study examined the prevalence of Helicobacter pylori and related factors in biopsies from the upper aerodigestive tract (UADT) in patients with gastric colonization by Helicobacter pylori.

METHODS
In a case series study, 26 patients with histopathologically confirmed gastric colonization were identified. A polymerase chain reaction (PCR) was performed on matched formalin-fixed and paraffin-embedded tissues of the stomach and the oral cavity, pharynx, or larynx.

RESULTS
Helicobacter pylori was found in 38% of the samples from the oral cavity, pharynx, and larynx. An association with malignancies in these regions or possible risk factors, such as age, smoking, or alcohol, was not found.

CONCLUSION
The upper aerodigestive system seems to be an additional reservoir in a significant percentage of patients presenting with Helicobacter pylori gastritis.