Publikation

Outcome in squamous cell carcinoma of the nasal vestibule: a single center experience

Wissenschaftlicher Artikel/Review - 15.04.2014

Bereiche
PubMed
DOI

Zitation
Vital D, Morand G, Huber G, Studer G, Holzmann D. Outcome in squamous cell carcinoma of the nasal vestibule: a single center experience. Head & neck 2014; 37:46-51.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Head & neck 2014; 37
Veröffentlichungsdatum
15.04.2014
eISSN (Online)
1097-0347
Seiten
46-51
Kurzbeschreibung/Zielsetzung

BACKGROUND
The purpose of this study was to analyze the outcome of squamous cell carcinomas (SCCs) of the nasal vestibule and to identify factors predicting recurrence.

METHODS
All patients treated between 1995 and 2012 were included in this study. Outcome was analyzed with respect to modality of therapy, age, sex, tobacco consumption, staging, surgical margins, and histological differentiation pattern.

RESULTS
Thirty patients were included. Fourteen patients (47%) were found with T4, 1 patient (3%) with T3, 7 patients (23%) with T2, and 8 patients (27%) with T1 disease. Twenty-one patients (70%) were treated surgically. Six patients (29%) needed postoperative radiation because of insufficient surgical margins. Radiation was the first-line treatment in 9 patients (30%). Surgically treated patients with surgical margins <3 mm had significantly more locoregional recurrence compared to those with sufficient resections.

CONCLUSION
Advanced T4 carcinomas show a high recurrence rate. Insufficient surgical margins are the main predictor for a locoregional recurrence and should be avoided.