Publikation

Favorable Thrombolysis Outcome in Diabetic Stroke Patients treated with Metformin

Konferenzpapier/Poster - 16.05.2017

Bereiche
Schlagwörter (Tags)
Metformin, diabetes, stroke, thrombolysis

Zitation
Westphal L, Engelter S, Kägi G, Scherrer M, Leys D, Pezzini A, Turc G, Béjot Y, Padjen V, Cautinho J, Zini A, Heldner M, Eskandari A, Polymeris A, Nolte C, Curtze S, Hametner C, Wegener S (2017). Favorable Thrombolysis Outcome in Diabetic Stroke Patients treated with Metformin.
Art
Konferenzpapier/Poster (Englisch)
Name der Konferenz
European Stroke Organisation Conference (ESOC) (-)
Veröffentlichungsdatum
16.05.2017
Kurzbeschreibung/Zielsetzung

In this multicenter exploratory data analysis, we tested if pretreatment with Metformin positively affects outcome of thrombolysis in acute ischemic stroke patients with diabetes.

Stroke patients pretreated with Metformin receiving thrombolysis had less severe strokes on admission and better functional outcome at 3 months. The effect was Independent of other clinical differences between Metformin users and non-users, as determined by propensity score matching.

Patients with diabetes may benefit from Metformin treatment, particularly if they are at high risk of stroke.