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AIM OF THE STUDY: To test a novel diagnostic technique, slit-lamp perimetry. PATIENTS AND METHODS: Slit-lamp perimetry is performed during a normal slit-lamp examination by projecting a small, round light mark onto the fundus. The light mark is moved and consecutively the patient is asked, if the light moved towards or away from the scotoma. Using the patients feedback the light mark can be placed exactly onto the retinal region corresponding to the scotoma. This method was tested on a patient with a microinfarction of a small retinal arteriole and on two patients with small preretinal parapapillary vitreous floaters. RESULTS: Slit-lamp perimetry correctly localized preretinal vitreous floaters and a fresh cotton wool spot missed on an dilated fundus examination. CONCLUSION: Slit-lamp perimetry is a novel rapid diagnostic technique to localize retinal and preretinal pathologies reponsibles for scotomas.