In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model

Publikation

In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model

Wissenschaftlicher Artikel/Review - 02.05.1998

Hornung René, Major Atilla L., McHale Michael, Liaw Lih-Huei L., Sabiniano Leslie A., Tromberg Bruce J., W. Berns Michael, Tadir Yona

Zitation

Hornung R, Major A, McHale M, Liaw L, Sabiniano L, Tromberg B, W. Berns M, Tadir Y. In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model. J am Assoc Gynecol Laparosc. 1998; 5:141-148.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

J am Assoc Gynecol Laparosc. 1998; 5

Veröffentlichungsdatum

02.05.1998

Seiten

141-148

Verlag

Elsevier Inc. (Philadephia (USA))

Kurzbeschreibung/Zielsetzung

To determine the feasibility of macroscopic visualization of small ovarian cancer metastases in vivo by fluorescence after intravenous administration of 5-aminolevulinic acid (ALA); to assess the time after drug injection when fluorescence of small metastases is maximum; and to correlate macroscopic in vivo fluorescence with both microscopic ex vivo fluorescence and histologic findings.