Historical epidemiology of hepatitis C virus (HCV) in selected countries

Publikation

Historical epidemiology of hepatitis C virus (HCV) in selected countries

Wissenschaftlicher Artikel/Review - 01.05.2014

Kåberg M, Myers R P, Negro F, Nemecek V, Örmeci N, Parkes J, Peltekian K M, Ramji A, Razavi H, Reis N, Mullhaupt B, Mendes Correa M C, Mauss S, Kaita K D E, Kautz A, Kaymakoglu S, Krajden M, Krarup H, Laleman W, Lavanchy D, Lázaro P, Marotta P, Roberts S K, Rosenberg W M, Vogel W, Waked I, Wedemeyer H, Weis N, Wiegand J, Yosry A, Zekry A, Van Damme P, Aleman S, Vandijck D, Van Vlierberghe H, van Thiel I, Sarmento-Castro R, Sarrazin C, Semela David, Shiha G E, Sievert W, Stärkel P, Stauber R E, Thompson A J, Urbanek P, Hindman S J, Idilman R, Bruggmann P, Bilodeau M, Blasco A J, Buti M, Calinas F, Calleja J L, Cheinquer H, Christensen P B, Clausen M, Coelho H S M, Bihl F, Balık I, Akarca U, Berg T, Øvrehus A L H, Moreno C, Brandão Mello C E, Roudot-Thoraval F, Marinho R T, Sherman M, Ryder S D, Sperl J, Cornberg M, Cramp M E, García-Samaniego J, Gerstoft J, Giria J A, Gonçales F L, Gower E, Gschwantler M, Guimarães Pessôa M, Hézode C, Hofer H, Frankova S, Ferreira P R, Ferraz M L G, Dore G J, Doss W, Duberg A S, El-Sayed M H, Ergör G, Esmat G, Estes C, Falconer K, Félix J, Husa P

Zitation

Kåberg M, Myers R, Negro F, Nemecek V, Örmeci N, Parkes J, Peltekian K, Ramji A, Razavi H, Reis N, Mullhaupt B, Mendes Correa M, Mauss S, Kaita K, Kautz A, Kaymakoglu S, Krajden M, Krarup H, Laleman W, Lavanchy D, Lázaro P, Marotta P, Roberts S, Rosenberg W, Vogel W, Waked I, Wedemeyer H, Weis N, Wiegand J, Yosry A, Zekry A, Van Damme P, Aleman S, Vandijck D, Van Vlierberghe H, van Thiel I, Sarmento-Castro R, Sarrazin C, Semela D, Shiha G, Sievert W, Stärkel P, Stauber R, Thompson A, Urbanek P, Hindman S, Idilman R, Bruggmann P, Bilodeau M, Blasco A, Buti M, Calinas F, Calleja J, Cheinquer H, Christensen P, Clausen M, Coelho H, Bihl F, Balık I, Akarca U, Berg T, Øvrehus A, Moreno C, Brandão Mello C, Roudot-Thoraval F, Marinho R, Sherman M, Ryder S, Sperl J, Cornberg M, Cramp M, García-Samaniego J, Gerstoft J, Giria J, Gonçales F, Gower E, Gschwantler M, Guimarães Pessôa M, Hézode C, Hofer H, Frankova S, Ferreira P, Ferraz M, Dore G, Doss W, Duberg A, El-Sayed M, Ergör G, Esmat G, Estes C, Falconer K, Félix J, Husa P. Historical epidemiology of hepatitis C virus (HCV) in selected countries. J Viral Hepat 2014; 21 Suppl 1:5-33.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

J Viral Hepat 2014; 21 Suppl 1

Veröffentlichungsdatum

01.05.2014

eISSN (Online)

1365-2893

Seiten

5-33

Kurzbeschreibung/Zielsetzung

Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.