Publikation

Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose: not yet!

Wissenschaftlicher Artikel/Review - 01.01.2002

Bereiche
PubMed

Zitation
Gueller U, Harder F, Oertli D, Marti W, Langer I, Moch H, Torhorst J, Viehl C, Schirp U, Nitzsche E, Zuber M. Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose: not yet!. Breast Cancer Res Treat 2002; 71:171-3.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Breast Cancer Res Treat 2002; 71
Veröffentlichungsdatum
01.01.2002
ISSN (Druck)
0167-6806
Seiten
171-3
Kurzbeschreibung/Zielsetzung

We prospectively evaluated 31 patients with invasive breast cancer. Preoperative positron emission tomography (PET) with 18F-fluoro-2-deoxy-D-glucose (18F-FDG) for detection of axillary lymph node metastases was compared with the histopathologic status of the sentinel lymph node (SLN). Sensitivity of PET imaging was 43%, specificity and negative predictive value were 94 and 67%, respectively. The smallest metastasis detected by PET measured 3 mm in diameter. The results of this study suggest that detection of small axillary lymph node metastases is limited by the currently achievable spatial resolution of PET imaging. Selective axillary surgery in breast cancer patients based on 18F-FDG PET is yet not possible.