Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx - Publikation

Publikation

Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx

Wissenschaftlicher Artikel/Review - 03.06.2011

Huber Gerhard F, Züllig Lena, Soltermann Alex, Roessle Matthias, Haerle Stephan K, Studer Gabriela, Jochum Wolfram, Moch Holger, Stöckli Sandro

Zitation

Huber G, Züllig L, Soltermann A, Roessle M, Haerle S, Studer G, Jochum W, Moch H, Stöckli S. Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx. BMC cancer 2011; 11:217:1-8.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

BMC cancer 2011; 11

Veröffentlichungsdatum

03.06.2011

eISSN (Online)

1471-2407

Seiten

217:1-8

Kurzbeschreibung/Zielsetzung

Prognostic factors in predicting occult lymph node metastasis in patients with head and neck squamous-cell carcinoma (HNSCC) are necessary to improve the results of the sentinel lymph node procedure in this tumour type. The E-Cadherin glycoprotein is an intercellular adhesion molecule in epithelial cells, which plays an important role in establishing and maintaining intercellular connections.