Publikation

Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx

Wissenschaftlicher Artikel/Review - 03.06.2011

Bereiche
PubMed
DOI

Zitation
Huber G, Züllig L, Soltermann A, Roessle M, Haerle S, Studer G, Jochum W, Moch H, Stöckli S. Down regulation of E-Cadherin (ECAD) - a predictor for occult metastatic disease in sentinel node biopsy of early squamous cell carcinomas of the oral cavity and oropharynx. BMC cancer 2011; 11:217:1-8.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
BMC cancer 2011; 11
Veröffentlichungsdatum
03.06.2011
eISSN (Online)
1471-2407
Seiten
217:1-8
Kurzbeschreibung/Zielsetzung

Prognostic factors in predicting occult lymph node metastasis in patients with head and neck squamous-cell carcinoma (HNSCC) are necessary to improve the results of the sentinel lymph node procedure in this tumour type. The E-Cadherin glycoprotein is an intercellular adhesion molecule in epithelial cells, which plays an important role in establishing and maintaining intercellular connections.