Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice

Publikation

Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice

Wissenschaftlicher Artikel/Review - 01.02.2004

Redaelli Claudio A, Semela David, Carrick Francine E, Ledermann Monika, Candinas Daniel, Sauter Bernhard, Dufour Jean-François

Bereiche

Gastroenterologie | Hepatologie

PubMed

14739103

Zitation

Redaelli C, Semela D, Carrick F, Ledermann M, Candinas D, Sauter B, Dufour J. Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice. J Hepatol 2004; 40:305-12.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

J Hepatol 2004; 40

Veröffentlichungsdatum

01.02.2004

ISSN (Druck)

0168-8278

Seiten

305-12

Kurzbeschreibung/Zielsetzung

Liver regeneration is dependent upon coordinated proliferation of hepatocytes and endothelial cells. Vascular endothelial growth factor (VEGF) promotes angiogenesis. Hepatic steatosis delays regeneration and increases liver resection morbidity. We hypothesized that VEGF overexpression stimulates hepatic regeneration.