Publikation

Preexposure prophylaxis and timed intercourse for HIV-discordant couples willing to conceive a child

Wissenschaftlicher Artikel/Review - 23.10.2011

Bereiche
PubMed
DOI

Zitation
Vernazza P, Graf I, Sonnenberg-Schwan U, Geit M, Meurer A. Preexposure prophylaxis and timed intercourse for HIV-discordant couples willing to conceive a child. AIDS 2011; 25:2005-8.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
AIDS 2011; 25
Veröffentlichungsdatum
23.10.2011
eISSN (Online)
1473-5571
Seiten
2005-8
Kurzbeschreibung/Zielsetzung

Many HIV-discordant couples express a strong wish to conceive a child. Insemination with processed semen is offered to these couples in many countries. Given the very low level of transmission risk during fully suppressive antiretroviral therapy, we offered timed intercourse combined with preexposure prophylaxis to further reduce the transmission risk. In 53 cases, natural conception was attempted using the proposed method. Pregnancy rates were high and reached a plateau of 75% after six cycles. Advanced age in the female partner was a predictor for infertility in these couples.