Publikation

18F-FDG-PET and MRI in patients with malignancies of the liver and pancreas. Accuracy of retrospective multimodality image registration by using the CT-component of PET/CT

Wissenschaftlicher Artikel/Review - 20.04.2010

Bereiche
PubMed
DOI

Zitation
Donati O, Reiner C, Hany T, Fornaro J, von Schulthess G, Marincek B, Weishaupt D. 18F-FDG-PET and MRI in patients with malignancies of the liver and pancreas. Accuracy of retrospective multimodality image registration by using the CT-component of PET/CT. Nuklearmedizin 2010; 49:106-14.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Nuklearmedizin 2010; 49
Veröffentlichungsdatum
20.04.2010
ISSN (Druck)
0029-5566
Seiten
106-14
Kurzbeschreibung/Zielsetzung

To evaluate the accuracy of retrospective rigid image registration and fusion between F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and magnetic resonance imaging (MRI) of the upper abdomen. PATIENTS, MATERIAL, METHODS: Image fusion of PET and MRI was performed in 30 patients with suspected malignancy of the liver or pancreas. Using a commercially available image fusion tool capable of rigid manual point-based registration, PET-Images were retrospectively registered and fused by matching eight homologous points in the 3D spoiled gradient echo (GRE) MRI sequences acquired in portal venous phase and in the CT-component of PET/CT. Two separate observers (R1, R2) assessed accuracy of image registration by determining the distances in the x-, y- and z-axis as well as the absolute distance between anatomical landmarks which differed from the landmarks chosen for registration. Quality of fusion was graded using a three point grading scale (1 poorly fused; 2 satisfactory fused; 3 correctly fused) and compared to hybrid PET/CT fusion.