Publikation
Prader-Willi syndrome is associated with activation of the innate immune system independently of central adiposity and insulin resistance
Wissenschaftlicher Artikel/Review - 05.05.2010
Viardot Alexander, Sze Lisa, Purtell Louise, Sainsbury Amanda, Loughnan Georgina, Smith Ellie, Herzog Herbert, Steinbeck Katharine, Campbell Lesley V
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Kurzbeschreibung/Zielsetzung
Subjects with Prader-Willi syndrome (PWS) have a reduced life expectancy due to cardiovascular disease. Increased systemic low-grade inflammation is postulated as a contributor, despite reported lower visceral fat mass and increased insulin sensitivity.