Publikation

Docetaxel, cisplatin, and fluorouracil; docetaxel and cisplatin; and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma: a randomized phase II trial of the Swiss Group for Clinical Cancer Research

Wissenschaftlicher Artikel/Review - 01.08.2007

Bereiche
PubMed
DOI

Zitation
Roth A, de Braud F, Seymour M, Widmer L, Glynne-Jones R, Leslie M, Wernli M, Maibach R, Rufibach K, Borner M, Köberle D, Saletti P, Bernhard J, Falk S, Stupp R, Fazio N, Swiss Group for Clinical Cancer Research. Docetaxel, cisplatin, and fluorouracil; docetaxel and cisplatin; and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma: a randomized phase II trial of the Swiss Group for Clinical Cancer Research. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007; 25:3217-23.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007; 25
Veröffentlichungsdatum
01.08.2007
eISSN (Online)
1527-7755
Seiten
3217-23
Kurzbeschreibung/Zielsetzung

PURPOSE: This randomized phase II trial evaluated two docetaxel-based regimens to see which would be most promising according to overall response rate (ORR) for comparison in a phase III trial with epirubicin-cisplatin-fluorouracil (ECF) as first-line advanced gastric cancer therapy. PATIENTS AND METHODS: Chemotherapy-naïve patients with measurable unresectable and/or metastatic gastric carcinoma, a performance status