Publikation

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

Wissenschaftlicher Artikel/Review - 11.01.2010

Bereiche
PubMed
DOI

Zitation
Rauch A, Hirschel B, Malinverni R, Moradpour D, Mullhaupt B, Witteck A, Beckmann J, Berg T, Bergmann S, Negro F, Telenti A, Bochud P, Swiss Hepatitis C Cohort Study, Heim M, Günthard H, Furrer H, Kutalik Z, Descombes P, Cai T, di Iulio J, Mueller T, Bochud M, Battegay M, Bernasconi E, Borovicka J, Colombo S, Cerny A, Dufour J, Swiss HIV Cohort Study. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology 2010; 138:1338-45, 1345.e1-7.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Gastroenterology 2010; 138
Veröffentlichungsdatum
11.01.2010
eISSN (Online)
1528-0012
Seiten
1338-45, 1345.e1-7
Kurzbeschreibung/Zielsetzung

Hepatitis C virus (HCV) induces chronic infection in 50% to 80% of infected persons; approximately 50% of these do not respond to therapy. We performed a genome-wide association study to screen for host genetic determinants of HCV persistence and response to therapy.