Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation - data from the Swiss transplant cohort study. - Publikation

Publikation

Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation - data from the Swiss transplant cohort study.

Wissenschaftlicher Artikel/Review - 01.02.2024

Deng Yun, Frischnknecht Lukas, Wehmeier Caroline, de Rougemont Olivier, Villard Jean, Ferrari-Lacraz Sylvie, Golshayan Délaviz, Gannagé Monique, Binet Françoise-Isabelle, Wirthmueller Urs, Sidler Daniel, Schachtner Thomas, Schaub Stefan, Nilsson Jakob

Zitation

Deng Y, Frischnknecht L, Wehmeier C, de Rougemont O, Villard J, Ferrari-Lacraz S, Golshayan D, Gannagé M, Binet F, Wirthmueller U, Sidler D, Schachtner T, Schaub S, Nilsson J. Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation - data from the Swiss transplant cohort study. Front Immunol 2024; 15:1355128.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Front Immunol 2024; 15

Veröffentlichungsdatum

01.02.2024

eISSN (Online)

1664-3224

Seiten

1355128

Kurzbeschreibung/Zielsetzung

Living donor (LD) kidney transplantation in the setting of ABO blood group incompatibility (ABOi) has been previously reported to be associated with increased risk for antibody-mediated rejection (ABMR). It is however unclear if the presence of pre-transplant donor specific antibodies (DSA) works as an additive risk factor in the setting of ABOi and if DSA positive ABOi transplants have a significantly worse long-term outcome as compared with ABO compatible (ABOc) DSA positive transplants.