Hemorrhagic Transformation in Noncardioembolic Acute Ischemic Stroke: MRI Analysis From PACIFIC-STROKE.

Publikation

Hemorrhagic Transformation in Noncardioembolic Acute Ischemic Stroke: MRI Analysis From PACIFIC-STROKE.

Wissenschaftlicher Artikel/Review - 01.05.2024

Chen Chih-Hao, Shoamanesh Ashkan, Colorado Pablo, Saad Feryal, Lemmens Robin, De Marchis Gian Marco, Caso Valeria, Xu Lizhen, Heenan Laura, Masjuan Jaime, Christensen Hanne, Connolly Stuart J, Khatri Pooja, Mundl Hardi, Hart Robert G, Smith Eric Edward

Zitation

Chen C, Shoamanesh A, Colorado P, Saad F, Lemmens R, De Marchis G, Caso V, Xu L, Heenan L, Masjuan J, Christensen H, Connolly S, Khatri P, Mundl H, Hart R, Smith E. Hemorrhagic Transformation in Noncardioembolic Acute Ischemic Stroke: MRI Analysis From PACIFIC-STROKE. Stroke 2024

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Stroke 2024

Veröffentlichungsdatum

01.05.2024

eISSN (Online)

1524-4628

Kurzbeschreibung/Zielsetzung

In the phase 2 PACIFIC-STROKE trial (Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following Acute Noncardioembolic Stroke), asundexian, an oral factor XIa inhibitor, did not increase the risk of hemorrhagic transformation (HT). In this secondary analysis, we aimed to investigate the frequency, types, and risk factors of HT on brain magnetic resonance imaging (MRI).