Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Publikation

Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Wissenschaftlicher Artikel/Review - 09.12.2023

Mylius Veit, Baars Jan Harald, Witt Karsten, Benninger David H, Ciampi de Andrade D, Kägi Georg, Bally Julien, Brugger Florian

Zitation

Mylius V, Baars J, Witt K, Benninger D, Ciampi de Andrade D, Kägi G, Bally J, Brugger F. Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception. Mov Disord 2023

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Mov Disord 2023

Veröffentlichungsdatum

09.12.2023

eISSN (Online)

1531-8257

Kurzbeschreibung/Zielsetzung

Dopamine exerts antinociceptive effects on pain in PD at cortical and spinal levels, whereas only cortical effects have been described for DBS, so far. By assessing the nociceptive flexion reflex (NFR) threshold at medication on, and DBS ON and OFF in two patients, we showed that DBS additionally decreases spinal nociception.