Publikation

BAG-S53P4 as an additive to bone allografts: A laboratory study using an uniaxial compression test.

Wissenschaftlicher Artikel/Review - 12.06.2015

Bereiche
PubMed
DOI
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Zitation
Putzer D, Fuchs J, Coraça-Huber D, Christoph A, Liebensteiner M, Nogler M. BAG-S53P4 as an additive to bone allografts: A laboratory study using an uniaxial compression test. J Orthop Res 2015; 33:1875-9.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
J Orthop Res 2015; 33
Veröffentlichungsdatum
12.06.2015
eISSN (Online)
1554-527X
Seiten
1875-9
Kurzbeschreibung/Zielsetzung

We want to address the clinical issue of too sparse supply of allograft in total hip replacement and ambitions of controlling the grain size distribution. Bioglass BAG-S53P4 was evaluated as a bone graft additive to chemically treated allografts with controlled grain size distribution. Allografts were chemically cleaned (CG) and mixed with BAG-S53P4 additive (BG) for comparison. All samples were compacted with a dropped weight apparatus and then underwent a uniaxial compression test. The yield limit was determined by a uniaxial compression test and density was recorded while flowability was calculated. There was no difference between the yield stress limit of BG and CG after compaction (p=0.432). Adding BAG-S53P4 reduced flowability and could indicate better interlocking mechanism between particles. Adding BAG-S53P4 seems to have no impact on the yield stress limit. The extended allografts withstand the compaction equally good which makes it a valid bone substitute in total hip replacement. An in vivo loaded study is needed before clinical use can be recommended.