Local administration of Mitomycin-C-Treated peripheral blood mononuclear cells (PBMCs) prolongs allograft survival in vascularized composite allotransplantation.

Publikation

Local administration of Mitomycin-C-Treated peripheral blood mononuclear cells (PBMCs) prolongs allograft survival in vascularized composite allotransplantation.

Wissenschaftlicher Artikel/Review - 17.11.2015

Radu Christian Andreas, Kiefer Jurij, Gebhard Martha Maria, Bigdeli Amir Khosrow, Schmidt Volker, Germann Guenter, Lehnhardt Marcus, Terness Peter, Kneser Ulrich, Kremer Thomas

Zitation

Radu C, Kiefer J, Gebhard M, Bigdeli A, Schmidt V, Germann G, Lehnhardt M, Terness P, Kneser U, Kremer T. Local administration of Mitomycin-C-Treated peripheral blood mononuclear cells (PBMCs) prolongs allograft survival in vascularized composite allotransplantation. Microsurgery 2015; 36:417-425.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Microsurgery 2015; 36

Veröffentlichungsdatum

17.11.2015

eISSN (Online)

1098-2752

Seiten

417-425

Kurzbeschreibung/Zielsetzung

VCA offers a potential treatment for extensive tissue defects. First results of systemic administration of Mitomycin C-treated PBMCs in VCA demonstrated a significant prolongation of allograft survival. The aim of this study is to evaluate if local administration of MMC-PBMCs prolongs allograft survival in allogeneic hind limb transplantations of the rat.