Collagen-Elastin and Collagen-Glycosaminoglycan Scaffolds Promote Distinct Patterns of Matrix Maturation and Axial Vascularization in Arteriovenous Loop-Based Soft Tissue Flaps.

Publikation

Collagen-Elastin and Collagen-Glycosaminoglycan Scaffolds Promote Distinct Patterns of Matrix Maturation and Axial Vascularization in Arteriovenous Loop-Based Soft Tissue Flaps.

Wissenschaftlicher Artikel/Review - 01.07.2017

Schmidt Volker, Wietbrock Johanna O, Leibig Nico, Gloe Torsten, Henn Dominic, Hernekamp J Frederik, Harhaus Leila, Kneser Ulrich

Zitation

Schmidt V, Wietbrock J, Leibig N, Gloe T, Henn D, Hernekamp J, Harhaus L, Kneser U. Collagen-Elastin and Collagen-Glycosaminoglycan Scaffolds Promote Distinct Patterns of Matrix Maturation and Axial Vascularization in Arteriovenous Loop-Based Soft Tissue Flaps. Ann Plast Surg 2017; 79:92-100.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Ann Plast Surg 2017; 79

Veröffentlichungsdatum

01.07.2017

eISSN (Online)

1536-3708

Seiten

92-100

Kurzbeschreibung/Zielsetzung

Autologous free flaps are the criterion standard for reconstructions of complex soft tissue defects; however, they are limited by donor-site morbidities. The arteriovenous (AV) loop model enables the generation of soft tissue constructs based on acellular dermal matrices with a functional microvasculature and minimal donor site morbidity. The ideal scaffold for AV loop-based tissue engineering has not been determined.