Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial).

Publikation

Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial).

Wissenschaftlicher Artikel/Review - 17.09.2022

Hemmingsen Mathilde Nejrup, Larsen Andreas, Weltz Tim K, Ørholt Mathias, Wiberg Sebastian, Bennedsen Anne Karen, Bille Camilla, Carstensen Lena Felicia, Jensen Lisa Toft, Bredgaard Rikke, Koudahl Vibeke, Schmidt Volker, Vester-Glowinski Peter, Hölmich LisbRosenkrantz, Sørensen Søren J, Bjarnsholt Thomas, Damsgaard Tine, Herly Mikkel

Zitation

Hemmingsen M, Larsen A, Weltz T, Ørholt M, Wiberg S, Bennedsen A, Bille C, Carstensen L, Jensen L, Bredgaard R, Koudahl V, Schmidt V, Vester-Glowinski P, Hölmich L, Sørensen S, Bjarnsholt T, Damsgaard T, Herly M. Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial). BMJ Open 2022; 12:e058697.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

BMJ Open 2022; 12

Veröffentlichungsdatum

17.09.2022

eISSN (Online)

2044-6055

Seiten

e058697

Kurzbeschreibung/Zielsetzung

Periprosthetic infection is one of the most severe complications following implant-based breast reconstruction affecting 5%-10% of the women. Currently, many surgeons apply antibiotics locally on the breast implant to reduce the risk of postoperative infection, but no randomised, placebo-controlled trials have tested the treatment's efficacy.