Publikation

Integrative population pharmacokinetic and pharmacodynamic dose finding approach of the new camptothecin compound namitecan (ST1968).

Wissenschaftlicher Artikel/Review - 03.06.2015

Bereiche
PubMed
DOI
Kontakt

Zitation
Joerger M, Hess D, Delmonte A, Gallerani E, Fasolo A, Gianni L, Cresta S, Barbieri P, Pace S, Sessa C. Integrative population pharmacokinetic and pharmacodynamic dose finding approach of the new camptothecin compound namitecan (ST1968). Br J Clin Pharmacol 2015; 80:128-38.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Br J Clin Pharmacol 2015; 80
Veröffentlichungsdatum
03.06.2015
eISSN (Online)
1365-2125
Seiten
128-38
Kurzbeschreibung/Zielsetzung

Namitecan is a new camptothecan compound undergoing early clinical development. This study was initiated to build an integrated pharmacokinetic (PK) and pharmacodynamic (PD) population model of namitecan to guide future clinical development.