Publikation

Prevalence of Transcriptionally Active HPV Infection in Tumor-Free Oropharyngeal Tissue of OPSCC-Patients.

Wissenschaftlicher Artikel/Review - 22.04.2022

Bereiche
PubMed
DOI
Kontakt

Zitation
Guarda V, Schroeder L, Pawlita M, Ikenberg K, Rupp N, Jochum W, Stoeckli S, Holzinger D, Broglie M. Prevalence of Transcriptionally Active HPV Infection in Tumor-Free Oropharyngeal Tissue of OPSCC-Patients. Front Oncol 2022; 12:835814.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Front Oncol 2022; 12
Veröffentlichungsdatum
22.04.2022
ISSN (Druck)
2234-943X
Seiten
835814
Kurzbeschreibung/Zielsetzung

The natural history of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) is still largely unknown. Since reports of second primary tumors (SPTs) in patients with HPV-related OPSCCs are increasing, a multifocal HPV infection, hinting a «virus-induced field effect», has been hypothesized. This study aimed to investigate the HPV-prevalence in normal appearing oropharyngeal tissue in patients with OPSCCs.