Publikation

Symptomatic Profiles of Patients With Polycythemia Vera: Implications of Inadequately Controlled Disease.

Wissenschaftlicher Artikel/Review - 23.11.2015

Bereiche
PubMed
DOI
Kontakt

Zitation
Geyer H, Scherber R, Kosiorek H, Dueck A, Kiladjian J, Xiao Z, Slot S, Zweegman S, Sackmann F, Fuentes A, Hernández-Maraver D, Döhner K, Harrison C, Radia D, Muxi P, Besses C, Cervantes F, Johansson P, Andreasson B, Rambaldi A, Barbui T, Bonatz K, Reiter A, Boyer F, Etienne G, Ianotto J, Ranta D, Roy L, Cahn J, Maldonado N, Barosi G, Ferrari M, Gale R, Birgegard G, Xu Z, Zhang Y, Sun X, Xu J, Zhang P, te Boekhorst P, Commandeur S, Schouten H, Pahl H, Griesshammer M, Stegelmann F, Lehmann T, Senyak Z, Vannucchi A, Passamonti F, Samuelsson J, Mesa R. Symptomatic Profiles of Patients With Polycythemia Vera: Implications of Inadequately Controlled Disease. J Clin Oncol 2015; 34:151-9.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
J Clin Oncol 2015; 34
Veröffentlichungsdatum
23.11.2015
eISSN (Online)
1527-7755
Seiten
151-9
Kurzbeschreibung/Zielsetzung

Polycythemia vera (PV) is a myeloproliferative neoplasm (MPN) associated with disabling symptoms and a heightened risk of life-threatening complications. Recent studies have demonstrated the effectiveness of JAK inhibitor therapy in patients with PV patients who have a history of prior hydroxyurea (HU) use (including resistance or intolerance), phlebotomy requirements, and palpable splenomegaly. We aimed to determine how these features contribute alone and in aggregate to the PV symptom burden.