Publikation

The impact of pre-transplant donor specific antibodies on the outcome of kidney transplantation - Data from the Swiss transplant cohort study.

Wissenschaftlicher Artikel/Review - 21.09.2022

Bereiche
PubMed
DOI
Kontakt

Zitation
Frischknecht L, Deng Y, Wehmeier C, de Rougemont O, Villard J, Ferrari-Lacraz S, Golshayan D, Gannagé M, Binet I, Wirthmueller U, Sidler D, Schachtner T, Schaub S, Nilsson J, Swiss Transplant Cohort Study. The impact of pre-transplant donor specific antibodies on the outcome of kidney transplantation - Data from the Swiss transplant cohort study. Front Immunol 2022; 13:1005790.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Front Immunol 2022; 13
Veröffentlichungsdatum
21.09.2022
eISSN (Online)
1664-3224
Seiten
1005790
Kurzbeschreibung/Zielsetzung

Pre-transplant donor specific antibodies (DSA), directed at non-self human leukocyte antigen (HLA) protein variants present in the donor organ, have been associated with worse outcomes in kidney transplantation. The impact of the mean fluorescence intensity (MFI) and the target HLA antigen of the detected DSA has, however, not been conclusively studied in a large cohort with a complete virtual cross-match (vXM).