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Established cerebrospinal fluid (CSF) biomarkers allow for earlier
and more accurate etiological diagnosis of cognitive impairment.
Information and counselling are needed both before and after biomarker-
supported diagnosis. The procedures for diagnostic lumbar
punctures and pre-analytical sample handling should follow published
consensus recommendations. The results must be interpreted in the
context of the other available history information and assessments.
Blood-based biomarkers and other non-invasive markers are expected
to become available for clinical practice soon. Consequently, a
broader usage of biomarkers is expected and may accelerate the
development of individually tailored prevention and treatment
approaches.
This article provides the recommendations of the
Swiss Memory Clinics for the use of biomarkers in clinical practice.