Publikation
Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage.
Wissenschaftlicher Artikel/Review - 02.10.2022
Gaastra Benjamin, Duncan Poppy, Bakker Mark K, Hostettler Isabel, Alg Varinder S, Houlden Henry, Ruigrok Ynte M, Galea Ian, Tapper Will, Werring David J, Bulters Diederik
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Nuclear factor erythroid 2-related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator of inflammation, oxidative injury and blood breakdown product clearance. The aim of this study was to identify whether genetic variation in NFE2L2 is associated with clinical outcome following aSAH.