Publikation

Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage.

Wissenschaftlicher Artikel/Review - 02.10.2022

Bereiche
PubMed
DOI
Kontakt

Zitation
Gaastra B, Duncan P, Bakker M, Hostettler I, Alg V, Houlden H, Ruigrok Y, Galea I, Tapper W, Werring D, Bulters D. Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage. Eur J Neurol 2022; 30:116-124.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Eur J Neurol 2022; 30
Veröffentlichungsdatum
02.10.2022
eISSN (Online)
1468-1331
Seiten
116-124
Kurzbeschreibung/Zielsetzung

Nuclear factor erythroid 2-related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator of inflammation, oxidative injury and blood breakdown product clearance. The aim of this study was to identify whether genetic variation in NFE2L2 is associated with clinical outcome following aSAH.