Publikation

Indeterminate dendritic cell tumor in the pancreas

Wissenschaftlicher Artikel/Review - 16.07.2020

Bereiche
PubMed
DOI
Kontakt

Zitation
Sortino R, Schmid M, El Baz Y, Loosen A, Tarantino I, Steffen T, Schmied B, Abbassi F. Indeterminate dendritic cell tumor in the pancreas. J Surg Case Rep 2020; 2020:rjaa208.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
J Surg Case Rep 2020; 2020
Veröffentlichungsdatum
16.07.2020
ISSN (Druck)
2042-8812
Seiten
rjaa208
Kurzbeschreibung/Zielsetzung

Indeterminate dendritic cell tumor (IDCT) is an extremely rare hematologic neoplastic disorder with proliferation of indeterminate dendritic cells. In the vast majority of cases, IDCTs are restricted to the skin or lymph nodes. To our knowledge, we report the first case of IDCT in the pancreas. Due to the rarity of extracutaneous IDCT, guidelines or treatment recommendations addressing their management are missing. We performed a review of literature to compare our experience to the management of other extracutaneous IDCT. Histopathological examination confirms the diagnosis of IDCT in electron microscopy and/or immunohistochemistry. Specific features are the lack of Birbeck granules and the nonreaction to Langerin antibodies. Concerning the aftercare of extracutaneous IDCT, we recommend a dermatological examination to rule out an additional cutaneous manifestation as well as annual blood examinations due to the association between IDCT and hematologic malignancies.